117 completed, 24 terminated, 20 recruiting, 11 withdrawn. 180 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 180 | Completed 117, Terminated 24, Recruiting 20, Withdrawn 11, Active not recruiting 3, Not yet recruiting 2, Enrolling by invitation 1, Suspended 1, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The EMBRACE Study: Enflonsia Monoclonal in Babies - RSV Antibody Concentration Evaluation Clesrovimab - RSV Infection | Phase 4 | Not yet recruiting | Emory University | 24 | 2026-09-01 | 2026-09-17 |
| Prophylactic Transfusion In Pregnant in Women With Sickle Cell Disease Prophylactic Transfusion Intervention group: Transfusion, Control group - Sickle Cell Disease, Pregnancy Related | Phase 4 | Withdrawn | Emory University | 2026-09-01 | 2026-10-19 | |
| Role of Suzetrigine as a Part of a Multimodal Regimen to Reduce Pain and Opioid Use After Total Knee Arthroplasty Suzetrigine - Knee Arthritis, Knee Osteoarthritis | Phase 4 | Not yet recruiting | Emory University | 75 | 2026-07-01 | 2026-06-03 |
| Comprehensive Toileting Program Glycerin Suppository, Behavioral strategies - Encopresis, ASD | Phase 4 | Recruiting | Emory University | 150 | 2026-06-01 | 2026-06-18 |
| MenB-FHbp or MenACWY-TT/MenB-FHbp Vaccine in MenB-4C Primed Young Adults Trumenba, PENBRAYA - Neisseria Meningitidis | Phase 4 | Recruiting | Emory University | 125 | 2025-11-04 | 2025-12-22 |
| Systems Biological Analysis of Immune Responses to RSV Vaccine Moderna RSV vaccine - Respiratory Syncytial Virus (RSV) | Phase 4 | Active not recruiting | Emory University | 14 | 2025-10-13 | 2026-08-12 |
| Got Doxy- 'Flipping the Script' on STI PEP Doxycycline monohydrate 200 mg, Observation - Sexually Transmitted Infections (STI) | Phase 4 | Recruiting | Emory University | 200 | 2025-10-13 | 2026-04-30 |
| Safety of RSV Preventive Monoclonal Antibody Respiratory Syncytial Virus (RSV) Preventive Monoclonal Antibody - Fever, Adverse Event Following Immunisation | Phase 4 | Recruiting | Duke University | 524 | 2025-10-02 | 2026-03-16 |
| Evaluating Premedication Regimens (Methylprednisolone vs Dexamethasone-based) for the Prevention of Systemic and Injection Site Reactions to Motixafortide in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization, PARADE Trial Acetaminophen, Biospecimen Collection, Dexamethasone - Multiple Myeloma | Phase 4 | Recruiting | Emory University | 94 | 2025-09-24 | 2026-07-23 |
| HPV Vaccine Reduced Dose Gardasil-9, Lidocaine injection, Lorazepam - HPV | Phase 4 | Recruiting | Emory University | 100 | 2025-08-06 | 2026-08-31 |
| Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases Moxidectin, Ivermectin - Onchocerciasis, Ascaris Lumbricoides Infection | Phase 4 | Recruiting | Kirby Institute | 52000 | 2025-08-04 | 2025-11-21 |
| Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease Depot medroxyprogesterone acetate (DMPA) - Sickle Cell Disease (SCD), Vaso-Occlusive Pain Episode in Sickle Cell Disease | Phase 4 | Recruiting | University of Pennsylvania | 65 | 2025-06-26 | 2026-05-28 |
| Trachoma Elimination Study by Focused Antibiotic (TESFA) Azithromycin mass treatment, Azithromycin targeted treatment - Trachoma | Phase 4 | Withdrawn | Emory University | 2025-06-01 | 2025-07-16 | |
| Modeling Ketosis-Prone Diabetes Remission Via Diverse Mechanisms of Glucotoxicity Continuous Glucose Monitoring, Insulin - Ketosis Prone Diabetes | Phase 4 | Recruiting | Emory University | 12 | 2025-01-23 | 2026-06-15 |
| Antihypertensive Mechanisms of Minocycline in Resistant Hypertension Minocycline Hydrochloride, Placebo - Hypertension, Resistant to Conventional Therapy | Phase 4 | Recruiting | University of Florida | 120 | 2025-01-08 | 2026-10-13 |
| Revealing Protective Immunity to Influenza Using Systems Immunology Live Attenuated Influenza Vaccine - Influenza | Phase 4 | Completed | Emory University | 51 | 2024-10-14 | 2026-03-30 |
| Daily Doxycycline to Inform Sexually Transmitted Infection Prophylaxis Regimens Doxycycline - Sexually Transmitted Infection | Phase 4 | Completed | Emory University | 24 | 2024-09-13 | 2026-05-01 |
| Chronic Exertional Compartment Syndrome (CECS) Treated With Abobotulinumtoxin A AbobotulinumtoxinA, Placebo - Compartment Syndrome of Leg | Phase 4 | Completed | Emory University | 3 | 2024-04-25 | 2025-10-21 |
| Anti-Inflammatory Challenge in Schizophrenia Infliximab, Placebo - Schizophrenia | Phase 4 | Recruiting | Emory University | 60 | 2024-04-18 | 2026-06-03 |
| Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction Concentrated Bone Marrow Aspirate Injection, Sham Incision, Revision Anterior Cruciate Ligament Reconstruction - Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee | Phase 4 | Recruiting | Hospital for Special Surgery, New York | 40 | 2024-01-22 | 2025-11-20 |
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Depression (16) · Diabetes Mellitus (15) · Diabetes Mellitus, Type 2 (15) · Depressive Disorder, Major (7) · Hyperglycemia (7) · Inflammation (5) · Influenza, Human (5) · Sexually Transmitted Diseases (5) · Stress Disorders, Post-Traumatic (5) · Acquired Immunodeficiency Syndrome (4) · Agnosia (4) · Cognitive Dysfunction (4) · Hypertension (4) · Pain (4) · Psychotic Disorders (4)
Insulin Glargine (17) · Insulin Aspart (11) · Insulin (9) · Insulin Lispro (9) · Escitalopram (7) · Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (6) · Saline Solution (6) · Bupivacaine (5) · Doxycycline (5) · Infliximab (5) · Lidocaine (5) · Sitagliptin Phosphate (5) · Standard of Care (5) · Calcium Dobesilate (4) · Cholecalciferol (4)
United States (167) · Angola (1) · Brazil (1) · Canada (1) · Israel (1) · Kenya (1) · Mexico (1) · Mozambique (1) · South Sudan (1)
Guillermo Umpierrez, MD (11) · Nadine Rouphael, MD (6) · Colleen Kelley, MD, MPH (5) · Guillermo E Umpierrez, MD (3) · Igho Ofotokun, MD, MSc (3) · Jennifer Felger, PhD (3) · John Xerogeanes, MD (3) · Ajay Premkumar, MD (2) · Andrew H Miller, MD (2) · Andrew Miller, MD (2) · Christina Rostad, MD (2) · Laura Gilbertson, MD (2) · Maya Fayfman, MD (2) · Philip T Ninan, MD (2) · Qiang Cai, MD, PhD (2)
PMID 41701614, PMID 19366972, PMID 30524702, PMID 11587154, PMID 12748199, PMID 12791627, PMID 14717616, PMID 1550069, PMID 17496462, PMID 17513708, PMID 17615254, PMID 17920917, PMID 18292756, PMID 18378867, PMID 19017758, PMID 19171788, PMID 19225527, PMID 19933869, PMID 20854139, PMID 21079049, PMID 21179973, PMID 21228246, PMID 21368772, PMID 22353759, PMID 22364141, PMID 22399505, PMID 22805498, PMID 22945416, PMID 22964160, PMID 23039824, PMID 23280269, PMID 23575741, PMID 23624296, PMID 23741398, PMID 23877988, PMID 24336012, PMID 24373307, PMID 25271011, PMID 25529904, PMID 25681236, PMID 25782693, PMID 26122686, PMID 26285691, PMID 26482774, PMID 26811165, PMID 26865594, PMID 26903303, PMID 27159290, PMID 27632067, PMID 27632069
P30CA138292 (2), R01MH109320 (2), 1RC3NS070646-01 (1), K23AI124913 (1), K23DK122199 (1), K23DK124647 (1), K23DK131317 (1), K23GM128221 (1), P50NS123103 (1), R01AG028769 (1), R01AI192319 (1), R01ES025775 (1), R01HD115933 (1), R01HL065523 (1), R01HL132448 (1)