51 completed, 5 unknown, 3 active not recruiting, 3 recruiting. 19 Phase 2, 15 Phase 4, 14 Phase 1, 13 Phase 3, 11 Not applicable.
Follow Theophylline: new trials by email Literature Review of Theophylline trials Research Report on Theophylline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Theophylline, Versus Sumatriptan and Gabapentin in The Treatment of Post-Dural Puncture Headache Theophylline, Sumatriptan, Gabapentin - Theophylline, Sumatriptan | Not applicable | Recruiting | Tanta University | 75 | 2024-12-01 | 2026-04-07 |
| Effect of Tigulixostat on the Pharmacokinetics of Theophylline Tigulixostat, Theophylline - Gout, Hyperuricemia | Phase 1 | Completed | LG Chem | 24 | 2023-10-31 | 2024-01-03 |
| Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage Single Dose Theophylline, Repeat Dose Theophylline - Acute Kidney Injury, HIE | Phase 1 / Phase 2 | Active not recruiting | Medical College of Wisconsin | 30 | 2023-10-17 | 2026-06-23 |
| Theophylline Effects in the Fontan Circulation Theophylline Tablets - Congenital Heart Disease | Phase 2 | Completed | Oslo University Hospital | 10 | 2023-02-09 | 2023-09-21 |
| Reversal of Complete Heart Block With Aminophylline in Inferior Wall Myocardial Infarction Patients Aminophylline Injection - Complete Heart Block, Inferior Wall Myocardial Infarction | Phase 4 | Withdrawn | National Institute of Cardiovascular Diseases, Pakistan | 2022-12-19 | 2025-05-25 | |
| Smell in COVID-19 and Efficacy of Nasal Theophylline (SCENT 3) theophylline, Placebo - COVID-19 | Phase 2 | Completed | Washington University School of Medicine | 77 | 2022-11-22 | 2025-08-20 |
| Reverse Triple Negative Immune Resistant Breast Cancer Choline, anti-PD-1 antibody and chemotherapy, Sodium Cromoglicate - Triple-negative Breast Cancer | Phase 2 | Recruiting | Fudan University | 90 | 2022-06-30 | 2026-10-23 |
| Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD Theophylline ER, Placebo oral tablet, Standard of Care Treatment - COPD, COPD Exacerbation | Phase 3 | Completed | University of Miami | 100 | 2021-02-23 | 2024-11-15 |
| The Effect of Oral Theophylline on Traumatic Anosmia Theophylline 200 mg, olfactory training - Traumatic Anosmia | Phase 4 | Completed | Taichung Veterans General Hospital | 158 | 2020-12-01 | 2025-09-12 |
| Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old Theophylline, Placebo - Pseudohypoparathyroidism, Albright Hereditary Osteodystrophy | Phase 2 | Active not recruiting | Vanderbilt University Medical Center | 34 | 2020-07-13 | 2026-04-29 |
| Diaphragmatic Ultrasound With Theophylline Therapeutic Trials Theophylline - Diaphragmatic Dysfunction in Critically Ill Patients | Early Phase 1 | Unknown | Assiut University | 46 | 2020-04-01 | 2020-02-13 |
| Is Theophylline More Effective Than Sumatriptan in the Treatment of Post-dural Puncture Headache Theophylline Anhydrous Oral Tablet, Sumatriptan Succinate Oral Tablet - Post-Dural Puncture Headache | Phase 4 | Completed | Damanhour Teaching Hospital | 60 | 2020-02-15 | 2021-06-03 |
| Effect of Theophylline in Pseudohypoparathyroidism Theophylline - PHP Ia, PHP IB | Phase 4 | Recruiting | Massachusetts General Hospital | 100 | 2019-11-11 | 2022-07-22 |
| Sphenopalatine Blockade Versus Clinical Treatment Dypirone, Sphenopalatine block, Ketoprofen - Headache, Post-Dural Puncture | Not applicable | Unknown | University of Sao Paulo General Hospital | 45 | 2019-09-20 | 2019-11-04 |
| Smell Changes & Efficacy of Nasal Theophylline Theophylline, Saline Nasal - Olfactory Disorder, Anosmia | Phase 2 | Completed | Washington University School of Medicine | 27 | 2019-05-15 | 2022-03-31 |
| The Effect of Doxapram Versus Theophylline on Diaphragmatic Function Doxapram Hydrochloride, Theophylline - Weaning Failure | Not applicable | Unknown | Beni-Suef University | 70 | 2019-05-01 | 2019-03-28 |
| Theophylline Treatment for Pseudohypoparathyroidism Theophylline, Placebos - Pseudohypoparathyroidism, Albright Hereditary Osteodystrophy | Phase 2 | Active not recruiting | Vanderbilt University Medical Center | 29 | 2018-09-01 | 2026-09-02 |
| PRISTINE - Personalised Approach to Improve aSThma prescrIbing iN childrEn Montelukast or Salmeterol or Theophylline or Steroid - Asthma | Phase 4 | Terminated | Brighton and Sussex University Hospitals NHS Trust | 2 | 2017-07-01 | 2019-12-18 |
| Association Study Between CYP1A2 Gene Polymorphisms and Metabolism of Theophylline Theophylline - Chronic Obstructive Pulmonary Disease | Not applicable | Completed | XiaoGuang Zou | 110 | 2017-01-01 | 2022-03-17 |
| Digital Image Correlation in Right Ventricular Evaluation Theophylline, Ventilator positive end expiratory pressure adjustment, Videorecording - Heart Ventricles | Not applicable | Completed | Tampere University Hospital | 20 | 2016-05-16 | 2021-12-08 |
Showing 20 of 66. Sign in to see all of them.
Pulmonary Disease, Chronic Obstructive (14) · Asthma (11) · Pseudohypoparathyroidism (4) · Anosmia (3) · Post-Dural Puncture Headache (3) · Altitude Sickness (2) · Bronchiectasis (2) · Carcinoma, Non-Small-Cell Lung (2) · Inflammation (2) · Acute Kidney Injury (1) · Apnea (1) · COVID-19 (1) · Depressive Disorder, Major (1) · Diarrhea (1) · Dysgeusia (1)
AstraZeneca (3) · Vanderbilt University Medical Center (3) · Boehringer Ingelheim (2) · Massachusetts General Hospital (2) · Mutual Pharmaceutical Company, Inc. (2) · Organon and Co (2) · The First Affiliated Hospital of Guangzhou Medical University (2) · Washington University School of Medicine (2) · Zhujiang Hospital (2) · AHS Cancer Control Alberta (1) · Assaf-Harofeh Medical Center (1) · Assiut University (1) · Baqiyatallah Medical Sciences University (1) · Beni-Suef University (1) · Brighton and Sussex University Hospitals NHS Trust (1)
United States (22) · China (7) · Canada (6) · United Kingdom (5) · Egypt (3) · Germany (3) · Norway (3) · Spain (3) · Iran (2) · Italy (2) · Australia (1) · Belgium (1) · Brazil (1) · Bulgaria (1) · Denmark (1)
Borja G Cosio, MD (2) · Chen Rongchang, Professor (2) · Jaclyn Tamaroff, MD (2) · Zhong Nanshan, Professor (2) · Ahmed M Shaat, MD (1) · Ahmed S Elmorsi, MD (1) · Andrew M Wilson (1) · Ashley H Shoemaker, MD, MSCI (1) · Azam Shafquat, MD (1) · Barrie March, MD (1) · Christine R Jenkins, MD (1) · Christopher Bell, PhD (1)
PMID 15356646, PMID 17075269, PMID 18922099, PMID 19007987, PMID 19158122, PMID 19196814, PMID 20299628, PMID 22563244, PMID 22829110, PMID 24525446, PMID 26680684, PMID 27107490, PMID 28877686, PMID 29717224, PMID 31847587, PMID 33334939, PMID 33726828, PMID 33917201, PMID 34849728, PMID 40563015
2004 (1), 2015 (1), K23HL146946 (1)