12 completed, 1 unknown. 13 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Completed 12, Unknown 1 |
| Phase 2 | 5 | Completed 4, Unknown 1 |
Follow Theophylline: new trials by email Literature Review of Theophylline trials Research Report on Theophylline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD Theophylline ER, Placebo oral tablet, Standard of Care Treatment - COPD, COPD Exacerbation | Phase 3 | Completed | University of Miami | 100 | 2021-02-23 | 2024-11-15 |
| Enhancement of Corticosteroid Efficacy in COPD Theophylline, Roflumilast - COPD | Phase 3 | Completed | UConn Health | 13 | 2014-12-01 | 2018-06-19 |
| Theophylline, N-acetylcysteine, and Theophylline Plus N-acetylcysteine in Preventing Contrast-induced Nephropathy N-acetylcysteine, Theophylline, 0.9% sodium chloride - Contrast-Induced Nephropathy | Phase 2 / Phase 3 | Unknown | Isfahan University of Medical Sciences | 96 | 2013-09-01 | 2014-03-17 |
| Drug Combination on Exercise Performance at High Altitude ambrisentan and theophylline, placebo - Acute Mountain Sickness | Phase 2 / Phase 3 | Completed | University of Montana | 28 | 2013-08-01 | 2016-02-26 |
| Low-dose Theophylline as Anti-inflammatory Enhancer in Severe Chronic Obstructive Pulmonary Disease theophylline, placebo - Chronic Obstructive Pulmonary Disease | Phase 3 | Completed | Hospital Son Espases | 70 | 2011-01-01 | 2017-08-29 |
| Study of MK-0476 in Adult Patients With Acute Asthma (0476-334) montelukast sodium, aminophylline hydrate - Asthma | Phase 3 | Completed | Organon and Co | 91 | 2007-03-01 | 2022-02-02 |
| Theophylline in Chronic Obstructive Pulmonary Disease Theophylline - COPD | Phase 2 / Phase 3 | Completed | Ottawa Hospital Research Institute | 24 | 2006-10-01 | 2017-07-07 |
| Efficacy & Safety of Symbicort® TURBUHALER® 160/4.5 µg Twice Daily & Pulmicort® TURBUHALER® 200 µg Twice Daily + Theolong® Tablet 200 mg Twice Daily in Japanese Asthmatic Patients Budesonide/Formoterol, Budesonide, Theophylline - Asthma | Phase 3 | Completed | AstraZeneca | 340 | 2005-10-01 | 2011-01-24 |
| Rosiglitazone Versus Theophylline in Asthmatic Smokers rosiglitazone, theophylline, beclomethasone - Asthma | Phase 2 / Phase 3 | Completed | University of Glasgow | 79 | 2005-07-01 | 2010-01-27 |
| DESOLO - SiT Peri-Launch: A Comparison of Symbicort Single Inhaler Therapy and Conventional Best Practice for the Treatment of Persistent Asthma in Adults Symbicort, used twice daily (b.i.d) and as needed (prn), Budesonide Turbuhaler 200 µg, Fluticasone Discus 250 µg - Asthma | Phase 3 | Completed | AstraZeneca | 1600 | 2004-12-01 | 2009-03-17 |
| CO2 Inhalation as a New Treatment Modality for Apnea of Prematurity CO2 inhalation, Theophylline - Apnea of Prematurity | Phase 2 / Phase 3 | Completed | University of Manitoba | 87 | 2001-08-01 | 2010-03-03 |
| Theophylline in Treating Cancer Patients With Shortness of Breath theophylline, quality-of-life assessment - Pulmonary Complications, Quality of Life | Phase 3 | Completed | NCIC Clinical Trials Group | 3 | 1998-03-24 | 2020-04-03 |
| NHLBI/NICHD Collaborative Studies of Asthma in Pregnancy theophylline, beclomethasone - Asthma, Lung Diseases | Phase 3 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 1994-04-01 | 2016-07-12 |
Asthma (5) · Pulmonary Disease, Chronic Obstructive (4) · Altitude Sickness (1) · Apnea (1) · Inflammation (1) · Lung Diseases (1) · Premature Birth (1) · Smoking (1)
AstraZeneca (2) · Hospital Son Espases (1) · Isfahan University of Medical Sciences (1) · NCIC Clinical Trials Group (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Organon and Co (1) · Ottawa Hospital Research Institute (1) · UConn Health (1) · University of Glasgow (1) · University of Manitoba (1) · University of Miami (1) · University of Montana (1)
Canada (3) · United States (2) · Germany (1) · Iran (1) · Japan (1) · Spain (1) · Uganda (1) · United Kingdom (1)
Borja G Cosio, MD (1) · Deborah J. Dudgeon, MD, RN (1) · Heinrich Worth, MD (1) · Mortaza Arabmomeni, M.D. (1) · Nausherwan Burki (1) · Neil C Thomson, MD (1) · Nha Voduc, MD (1) · Ruben E Alvaro, MD (1) · Trishul Siddharthan, MD (1)
PMID 19196814, PMID 22563244, PMID 27107490, PMID 33726828
2004 (1), K23HL146946 (1)