17 completed, 6 unknown, 1 active not recruiting, 1 recruiting. 27 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 27 | Completed 17, Unknown 6, Active not recruiting 1, Recruiting 1, Terminated 1, Withdrawn 1 |
Follow Lithium Carbonate: new trials by email Literature Review of Lithium Carbonate trials Research Report on Lithium Carbonate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bioequivalence Study of Lithium Carbonate 300 mg Tablets. Actilitio® in Healthy Subjects Theralite®, Actilitio® - Healthy, Healthy Donors | Phase 4 | Active not recruiting | Centro de Atencion e Investigacion Medica | 24 | 2024-06-01 | 2025-03-06 |
| Lithium Versus Lamotrigine in Bipolar Disorder, Type II Lithium Carbonate, Lamotrigine - Bipolar II Disorder | Phase 4 | Recruiting | University Hospital Bispebjerg and Frederiksberg | 200 | 2024-05-08 | 2026-03-20 |
| Effect of Lithium Carbonate on Postoperative Sleep and Cognitive Function in Patients Undergoing Heart Valve Surgery With Cardiopulmonary Bypass Lithium Carbonate 250 MG Oral Tablet, Calcium Carbonate 500 MG Oral Tablet - Heart Valve Surgery | Phase 4 | Unknown | China Medical University, China | 62 | 2023-07-01 | 2023-07-18 |
| Efficacy and Safety of Peropirone Hydrochloride Tablets in the Treatment of Adolescent Bipolar Disorder Depression Perospirone hydrochloride tablets, Lithium carbonate + perospirone hydrochloride, Lithium Carbonate Pill - Depressive Disorder | Phase 4 | Unknown | Shanghai Mental Health Center | 189 | 2020-11-25 | 2021-04-01 |
| Effect of Lithium Carbonate on Postoperative Sleep in Patients Undergoing Videoassisted Thoracic Surgery Lithium Carbonate 250 MG, Calcium Carbonate 500 MG - Sleep Deprivation | Phase 4 | Completed | China Medical University, China | 51 | 2020-11-06 | 2022-02-04 |
| Effect of Regulated Add -on Sodium Chloride Intake on Stabilization of Serum Lithium Concentration in Bipolar Disorder Lithium Carbonate, Sodium chloride - Bipolar Affective Disorder | Phase 4 | Completed | All India Institute of Medical Sciences, Bhubaneswar | 60 | 2020-01-16 | 2022-01-25 |
| RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT) Aripiprazole Augmentation, Bupropion Augmentation, Switch to bupropion - Depression, Dementia | Phase 4 | Completed | Centre for Addiction and Mental Health | 87 | 2019-08-01 | 2024-11-25 |
| Lithium As a Treatment to Prevent Impairment of Cognition in Elders Lithium Carbonate, Placebo oral capsule - Mild Cognitive Impairment | Phase 4 | Completed | Ariel Gildengers, MD | 83 | 2018-02-02 | 2025-09-11 |
| Guidance Model of Standardized Treatment of Antidepressants in Bipolar Disorder Lithium Carbonate, lithium carbonate combined with SSRI antidepressant treatment - the Use of Antidepressants in Patients With Bipolar Depression | Phase 4 | Unknown | Peking University | 100 | 2017-06-01 | 2017-05-11 |
| Lithium in Acute Kidney Injury Placebo oral capsule, Lithium Carbonate - Acute Kidney Injury | Phase 4 | Unknown | Lifespan | 50 | 2017-04-01 | 2017-02-17 |
| Optimizing Outcomes of Treatment-Resistant Depression in Older Adults Aripiprazole Augmentation, Bupropion Augmentation, Switch to bupropion - Treatment Resistant Depression, Major Depressive Disorder | Phase 4 | Completed | Washington University School of Medicine | 742 | 2017-02-24 | 2024-10-03 |
| Comparative Efficacy and Acceptability of Antimanic Drugs in Acute Mania Lithium, Valproate, Oxcarbazepine - Bipolar Disorder | Phase 4 | Unknown | Guiyun Xu | 120 | 2013-09-01 | 2015-03-17 |
| Clinical Trial of Lithium Carbonate Combined With Neo-adjuvant Chemotherapy to Treat Osteosarcoma Lithium Carbonate, Placebo - Osteosarcoma | Phase 4 | Unknown | Sun Yat-sen University | 400 | 2013-01-01 | 2016-11-01 |
| Gao Bipolar Spectrum Lithium/Quetiapine Study Lithium, Quetiapine - Bipolar Disorder | Phase 4 | Terminated | University Hospitals Cleveland Medical Center | 42 | 2012-01-01 | 2017-08-16 |
| Lithium Versus Paroxetine in Major Depression Lithium, Paroxetine - Major Depressive Disorder | Phase 4 | Withdrawn | Nova Scotia Health Authority | 2011-09-01 | 2024-09-19 | |
| Sequential Multiple Assignment Treatment for Bipolar Disorder Lithium, Divalproex, Lamotrigine - Bipolar I Disorder, Bipolar II Disorder | Phase 4 | Completed | The University of Texas Health Science Center at San Antonio | 112 | 2011-06-01 | 2020-08-19 |
| Comparative Effectiveness Study for Bipolar Disorder Lithium, Quetiapine - Bipolar Disorder | Phase 4 | Completed | Massachusetts General Hospital | 482 | 2010-09-01 | 2018-04-26 |
| Cost- Effectiveness and Quality of Life Assessment in Bipolar Disorder Depressive Episode Lithium Carbonate, Sertraline, Nortriptyline - Bipolar Disorder | Phase 4 | Completed | Federal University of Rio Grande do Sul | 78 | 2010-05-01 | 2020-11-20 |
| Cost- Effectiveness and Quality of Life Assessment in Major Depression Disorder sertraline, Nortriptyline, Lithium - Depression | Phase 4 | Completed | Federal University of Rio Grande do Sul | 68 | 2010-05-01 | 2020-10-14 |
| Prevention of Relapse & Recurrence of Bipolar Depression Lithium / Fluoxetine, Lithium / Placebo - Bipolar Disorder | Phase 4 | Completed | University of Pennsylvania | 177 | 2009-07-01 | 2020-10-19 |
Showing 20 of 27. Sign in to see all of them.
Bipolar Disorder (15) · Depression (4) · Depressive Disorder, Major (4) · Alzheimer Disease (2) · Cognitive Dysfunction (2) · Dementia (2) · Depressive Disorder (2) · Depressive Disorder, Treatment-Resistant (2) · Mania (2) · Acute Kidney Injury (1) · Familial paroxysmal dystonia (1) · Osteosarcoma (1) · Patient Dropouts (1) · Pick Disease of the Brain (1) · Plaque, Amyloid (1)
China Medical University, China (2) · Federal University of Rio Grande do Sul (2) · University of Pennsylvania (2) · All India Institute of Medical Sciences, Bhubaneswar (1) · Ariel Gildengers, MD (1) · Centre for Addiction and Mental Health (1) · Centro de Atencion e Investigacion Medica (1) · Guiyun Xu (1) · Lifespan (1) · Massachusetts General Hospital (1) · Melbourne Health (1) · National Institute of Mental Health (NIMH) (1) · Nova Scotia Health Authority (1) · Peking University (1) · Shanghai Mental Health Center (1)
United States (12) · China (6) · Canada (3) · Australia (1) · Colombia (1) · Denmark (1) · India (1) · Sweden (1)
Marcelo Fleck, PhD (2) · Robert J. DeRubeis, PhD (2) · Andrew A Nierenberg, MD (1) · Ariel Gildengers, MD (1) · Aristotle Voineskos, MD (1) · Axel Nordenskjold, MD (1) · Charles L. Bowden, M.D. (1) · Claire O'Donovan, MD, FRCPC (1) · Debra A Glitz, MD (1) · Eric Lenze, MD (1) · Gregor E Berger, MD (1) · Gregory J Moore, MD, PhD (1) · Guinyun Xu, M.D (1)
PMID 28832750, PMID 10511011, PMID 10588403, PMID 10913502, PMID 11072948, PMID 19389332, PMID 19472307, PMID 21157303, PMID 22076437, PMID 23288387, PMID 23303421, PMID 23670706, PMID 23876346, PMID 23911057, PMID 24408869, PMID 24535092, PMID 25035570, PMID 25514063, PMID 26143402, PMID 26476489, PMID 26803764, PMID 26845264, PMID 26845265, PMID 26892848, PMID 27122541, PMID 27805299, PMID 28160351, PMID 28188565, PMID 29136600, PMID 29149756, PMID 31401903, PMID 34195206, PMID 34523118, PMID 36409058, PMID 36867173, PMID 38232249, PMID 38822571, PMID 40501510, PMID 41237789, PMID 41401709, PMID 41677164, PMID 41770546, PMID 42103384
2023 (1), N01MH080001 (1), P30MH086045 (1), R01AG055389 (1), R01MH060353 (1), R01MH080097 (1), R01MH080098 (1), R01MH114966 (1), R01MH114970 (1), R01MH114980 (1), R01MH114981 (1)