6 completed, 4 not yet recruiting, 1 active not recruiting, 1 enrolling by invitation. 9 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 4.
Follow Wound Closure: new trials by email Literature Review of Wound Closure trials Research Report on Wound Closure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness and Costs of Pressure Ulcer Treatment and the Quality of Life of Patients With Pressure Ulcers Receiving Home-Based and Institutional Care residential home care treatment, long-term care treatment - Pressure Ulcer (PU), Pressure Ulcers, Bedsores, Decubitus Ulcer | Not applicable | Not yet recruiting | The Jerzy Kukuczka Academy of Physical Education in Katowice | 80 | 2026-09-01 | 2026-08-13 |
| Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Diabetic Foot Ulcers PRFM, Standard of Care (SoC) - Diabetic Foot Ulcer (DFU), Ulcer | Phase 1 / Phase 2 | Not yet recruiting | Tiger Biosciences, LLC. | 55 | 2026-09-01 | 2026-09-25 |
| Safety Study of Microlyte DualGuard Microlyte DualGuard, Allevyn Foam (Standard of Care Control) - Wound Closure, Wound Care | Not applicable | Not yet recruiting | Imbed Biosciences | 53 | 2026-08-30 | 2026-07-10 |
| Using TropoCells(R) Autologous Platelet-Rich Fibrin (PRF) to Treat Chronic Non-Healing Wounds Platelet-rich fibrin (PRF) - Wound Chronic Draining, Wound Closure | Phase 2 | Not yet recruiting | Estar Medical dba Medical Technologies, LTD | 16 | 2026-01-01 | 2026-01-06 |
| Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures STRATAFIX PDS and Monocryl suture - Wound Closure, Brain Tumor Adult | Phase 4 | Recruiting | University of Michigan | 160 | 2025-11-01 | 2025-11-05 |
| Dyed vs. Undyed Polyglactin Sutures in Cutaneous Surgery Polyglactin 910 (Dyed), Polyglactin 910 (Undyed) - Wound Closure, Suture Materials | Not applicable | Enrolling by invitation | West Virginia University | 50 | 2025-08-01 | 2025-07-22 |
| This Observational Study Evaluates the Clinical Outcomes of Patients With Diabetes Who Utilize a Specialized Dietary Supplements for Foot Ulcer Healing. The Study Documents the Rate of Complete Wound Closure and the Prevention of Lower Extremity Amputations in a Real-world, At-home Setting. Diabetic foot ulcer treatment by dietary supplements - Limb Salvage, Diabetes Complication | Completed | Amar h Zireg | 35 | 2025-07-05 | 2026-03-04 | |
| Efficacy of Using Knotless Barbed Suture vs N-Butyl Cyanoacrylate Glue Tissue Adhesive for Closure of Intraoral Surgical Incisions PDO Knotless Barbed Suture, N-Butyl Cyanoacrylate Glue (PERIACRYL), 3/0 Resorbable PGA Suture - Non-restorable Teeth, Intraoral Surgical Incisions | Not applicable | Active not recruiting | Future University in Egypt | 30 | 2025-06-16 | 2026-03-25 |
| Post Operative Skin Approximation With Cyanoacrylate Based Wound Closure Adhesives Evaluating wound closure products to close larger surgical site incisions, Evaluating wound closure products to close smaller surgical site incisions - Wound Closure, Dehisced Surgical Wounds | Not applicable | Completed | Medline Industries | 60 | 2025-04-02 | 2026-05-29 |
| Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery Sub-Incisional Pocket - Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up) | Completed | Philippine Eye Research Institute | 35 | 2025-01-01 | 2026-09-15 | |
| Effective Hemostasis: An Analysis of Hemostatic Sponges Used in Extraction Procedures Hemostatic sponge post tooth extraction - Hemostasis, Wound Closure | Not applicable | Completed | Universidad Nacional de Caaguazu | 30 | 2024-08-08 | 2026-04-14 |
| Symmetric on Total Knee Arthroplasty (TKA) "STRATAFIX™ Symmetric" Knotless Tissue, VICRYL® PLUS, "STRATAFIX Spiral" sutures - Wound Closure | Not applicable | Completed | Johnson & Johnson Medical, China | 184 | 2017-06-12 | 2020-01-13 |
| Comparison of Cyanoacrylate Adhesives to Sutures in the Palate After Connective Tissue Graft n-butyl cyanoacrylate and 2-octyl cyanoacrylate, 5-0 Polytetrafluoroethylene (PTFE) suture - Wound Closure | Not applicable | Unknown | University of Manitoba | 32 | 2017-01-09 | 2017-10-26 |
| Prospective Evaluation of the iTClamp50 to Provide Temporary Wound Closure iTClamp50 - Hemorrhage, Wound Closure | Withdrawn | Innovative Trauma Care Inc. | 2013-08-01 | 2013-12-19 | ||
| A Comparative Study of Incision Closure Methods for Total Knee Replacement Histoacryl Tissue Adhesive, Dermabond, Staples - Total Knee Replacement Closure, Wound Closure | Not applicable | Completed | Foundation for Southwest Orthopedic Research | 75 | 2009-01-01 | 2012-08-22 |
Diabetic Foot (2) · Brain Injuries, Traumatic (1) · Brain Neoplasms (1) · Cataract (1) · Diabetes Complications (1) · Diabetes Mellitus (1) · Hemorrhage (1) · Hemorrhagic Stroke (1) · Pain (1) · Pain, Postoperative (1) · Postoperative Complications (1) · Pressure Ulcer (1) · Ulcer (1)
Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Cardiovascular Diseases (3) · Skin Diseases (3) · Skin Ulcer (3) · Skin and Connective Tissue Diseases (3) · Vascular Diseases (3) · Diabetic Angiopathies (2) · Diabetic Neuropathies (2) · Endocrine System Diseases (2) · Foot Ulcer (2) · Leg Ulcer (2) · Neurologic Manifestations (2) · Signs and Symptoms (2) · Brain Diseases (1)
Sutures (2) · Standard of Care (1)
Amar h Zireg (1) · Estar Medical dba Medical Technologies, LTD (1) · Foundation for Southwest Orthopedic Research (1) · Future University in Egypt (1) · Imbed Biosciences (1) · Innovative Trauma Care Inc. (1) · Johnson & Johnson Medical, China (1) · Medline Industries (1) · Philippine Eye Research Institute (1) · The Jerzy Kukuczka Academy of Physical Education in Katowice (1) · Tiger Biosciences, LLC. (1) · Universidad Nacional de Caaguazu (1) · University of Manitoba (1) · University of Michigan (1) · West Virginia University (1)
United States (6) · Canada (2) · Algeria (1) · China (1) · Egypt (1) · Paraguay (1) · Philippines (1) · Poland (1)
Abeer Kamal, PHD (1) · Anna Polak, Prof. (1) · Chrysi Stavropoulou, DDS (1) · Kevin Foster, MD, MBA, FACS (1) · Lobna Abdel Aziz, PHD (1) · Mahmoud Mohsen El Arini, PHD (1) · Michael Karsy, MD, PhD, MSc (1) · Patty Schleckser (1) · Sarah Camplbell, MD (1) · Scott Dupar, Physician - Doctor of Medicine (1) · Sofia Monzon, DDs (1)
PMID 10759649, PMID 11203571, PMID 12795787, PMID 12966242, PMID 1453307, PMID 14663804, PMID 15128170, PMID 15857066, PMID 17502712, PMID 17712674, PMID 18626248, PMID 19464207, PMID 2183824, PMID 2196101, PMID 23089654, PMID 24431849, PMID 24494804, PMID 24562700, PMID 25644302, PMID 27041892, PMID 279662, PMID 279663, PMID 3866056, PMID 4594350, PMID 6394736, PMID 6694493