9 completed, 3 terminated, 3 unknown, 1 withdrawn. 11 Not applicable, 2 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 6, Terminated 3, Unknown 2 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Weakness: new trials by email Literature Review of Weakness trials Research Report on Weakness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Improving Safety of Diagnosis and Therapy in the Inpatient Setting Diagnostic Uncertainty Educational Curriculum, Diagnostic Timeout, Patient Diagnostic (Dx) Questionnaire - Delirium, Confusion | Not applicable | Completed | Brigham and Women's Hospital | 700 | 2019-07-01 | 2022-07-26 |
| Treatment of Muscle Weakness in Critically Ill Patients Sham Treatment, Electrical stimulation - Critical Illness, Respiratory Failure | Not applicable | Terminated | Gerald Supinski | 2 | 2016-12-01 | 2020-06-22 |
| Dedicated Ambulator-assisted Physical Activity to Improve Hospital Outcome Measures in Elderly Patients Ambulation - Weakness, Hospital Acquired Condition | Not applicable | Completed | The Cleveland Clinic | 102 | 2016-07-01 | 2017-08-10 |
| Early Cycloergometric Physiotherapy in Critically Ill Patients With Invasive Mechanical Ventilation Cycle ergometer physiotherapy, Conventional physiotherapy - Weakness | Not applicable | Unknown | Hospital Son Llatzer | 68 | 2015-06-01 | 2019-08-08 |
| Effects of the Cross-Training in Patients With Multiple Sclerosis Cross-Training healthy subjects, Cross-Training multiple sclerosis, Standard-training multiple sclerosis - Multiple Sclerosis, Weakness | Not applicable | Completed | Università degli Studi di Sassari | 45 | 2013-07-01 | 2017-03-29 |
| Evaluation of Thermal-Aided Muscle Stimulation Thermal-aided muscle stimulation, Body Temperature Stimulation - Weakness, Atrophy | Not applicable | Unknown | Niveus Medical, Inc. | 20 | 2013-07-01 | 2013-07-30 |
| Effect of Different Electric Muscle Stimulation in Patients With Severe Sepsis and Respiratory Failure EMS - Severe Sepsis, Acute Respiratory Failure | Not applicable | Terminated | Mackay Memorial Hospital | 25 | 2013-06-01 | 2019-07-08 |
| Effect of All-Stim 2 Quadriceps Treatments on Limb Muscle Strength In Mechanically Ventilated Patients Active electrical stimulation using an All Stim stimulator, Sham electrical stimulation using an All Stim stimulator - Weakness | Not applicable | Terminated | Gerald Supinski | 15 | 2013-01-03 | 2022-03-02 |
| Effect of Therapeutic Modalities on the Physical Fitness and Functional Capacity in Critical Patient kinetics modalities - Physical Deconditioning, Weakness | Not applicable | Completed | CES University | 24 | 2011-08-01 | 2013-06-19 |
| Clinical Trial of CoQ10 for Mild-to-Moderate Statin-Associated Muscle Symptoms Coenzyme Q10, Placebo - Pain, Weakness | Phase 2 / Phase 3 | Completed | Catherine Buettner | 68 | 2009-12-01 | 2017-01-23 |
| Benefit of CoQ-10 in Patients on Statins Co-enzyme Q-10, Placebo - Pain, Soreness | Not applicable | Completed | Stony Brook University | 37 | 2009-09-01 | 2016-05-02 |
| Utility of the History and Physical Exam in the Emergency Department Abdominal Pain, Back Pain | Completed | Henry Ford Health System | 128 | 2009-07-01 | 2010-07-01 | |
| A Randomised Controlled Trial of Family Mediated Exercises (FAME) Following Stroke Family Mediated Exercise Therapy - Weakness, Balance | Phase 3 | Unknown | University of Dublin, Trinity College | 40 | 2008-04-01 | 2008-10-29 |
| Muscle Atrophy in Sepsis Atrophy, Sepsis | Withdrawn | Gregory A. Schmidt | 2007-12-01 | 2017-02-28 | ||
| Use of Surface Electromyography Biofeedback to Improve Reaching in Children With Cerebral Palsy surface EMG biofeedback - Cerebral Palsy, Weakness | Completed | University of Southern California | 20 | 2007-05-01 | 2014-05-23 | |
| Effectiveness of Creatine in Preventing Muscle Aching From Cholesterol-Lowering Statin Drugs Creatine - Hypercholesterolemia, Aches | Not applicable | Completed | The Cleveland Clinic | 12 | 2006-08-01 | 2008-11-25 |
Asthenia (16) · Pain (3) · Sepsis (3) · Abdominal Pain (2) · Atrophy (2) · Back Pain (2) · Dyspnea (2) · Fatigue (2) · Headache (2) · Muscle Cramp (2) · Muscle Weakness (2) · Myalgia (2) · Respiratory Insufficiency (2) · Asthma (1) · Cellulitis (1)
Pathological Conditions, Signs and Symptoms (16) · Signs and Symptoms (16) · Nervous System Diseases (9) · Neurologic Manifestations (8) · Pathologic Processes (7) · Musculoskeletal Diseases (5) · Neuromuscular Manifestations (5) · Muscular Diseases (4) · Respiration Disorders (4) · Respiratory Tract Diseases (4) · Disease Attributes (3) · Infections (3) · Neuromuscular Diseases (3) · Systemic Inflammatory Response Syndrome (3) · Immune System Diseases (2)
Creatine (1) · Electric Stimulation (1) · Exercise (1) · Surveys and Questionnaires (1) · Ubiquinone (1) · Walking (1) · coenzyme Q10 (1)
Gerald Supinski (2) · The Cleveland Clinic (2) · Brigham and Women's Hospital (1) · CES University (1) · Catherine Buettner (1) · Gregory A. Schmidt (1) · Henry Ford Health System (1) · Hospital Son Llatzer (1) · Mackay Memorial Hospital (1) · Niveus Medical, Inc. (1) · Stony Brook University (1) · University of Dublin, Trinity College (1) · University of Southern California (1) · Università degli Studi di Sassari (1)
United States (11) · Colombia (1) · Ireland (1) · Italy (1) · Spain (1) · Taiwan (1)
Aaron Hamilton, MD (1) · Anuj K Dalal, MD (1) · Catherine Buettner, MD, MPH (1) · David A Shewmon, MD (1) · David W Bates, MD, MSc (1) · Emma Stokes, PhD (1) · Franca Deriu, MD; PhD (1) · Gemma Rialp, M.D. (1) · Gerald S Supinski, MD (1) · Gerald S. Supinski, MD (1) · Giuseppe Caso, MD, PhD (1) · Jennifer Stevenson, DO (1) · Kuang H Cheng, Msc (1) · Tara Cusack, PhD (1)
PMID 12472328, PMID 18570643, PMID 19446324, PMID 19623052, PMID 20046132, PMID 20406506, PMID 22147819, PMID 25715872, PMID 25922111, PMID 26637645, PMID 27485469, PMID 28251398, PMID 28342828, PMID 31100700, PMID 32266379, PMID 40066282
K23AR055664 (1)