64 completed, 21 unknown, 14 terminated, 11 recruiting. 83 Not applicable, 5 Phase 2, 3 Phase 3, 3 Phase 4, 1 Early Phase 1.
Follow Ventral Hernia: new trials by email Literature Review of Ventral Hernia trials Research Report on Ventral Hernia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery PT Group, Usual Care - Ventral Hernia, Ventral Incisional Hernia | Not applicable | Not yet recruiting | Thomas Jefferson University | 60 | 2027-07-01 | 2026-10-22 |
| Image-Guided Herniorrhaphy Study Image-Guided Herniorrhaphy - Hernia, Hernia Abdominal Wall | Not applicable | Not yet recruiting | University of California, Davis | 30 | 2026-12-01 | 2026-08-31 |
| Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia Repair Cryoneurolysis - Ventral Hernia, Incisional Hernia | Not applicable | Not yet recruiting | University of South Florida | 10 | 2026-11-01 | 2026-10-15 |
| Duramesh Versus Minimally Invasive IPOM for High-Risk Umbilical Hernia Repairs Duramesh, Mesh - Umbilical Hernia, Ventral Hernia | Not applicable | Recruiting | Northwestern University | 160 | 2026-10-01 | 2026-10-23 |
| Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release Bupivicaine, Fentanyl, Thoracic epidural analgesia - Ventral Hernia, Ventral Hernia Repair | Phase 4 | Recruiting | Northwestern University | 40 | 2026-09-25 | 2026-10-07 |
| Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair - Incisional Hernia, Abdominal Hernia | Not applicable | Recruiting | Minia University | 180 | 2026-08-15 | 2026-08-18 |
| Risk Factors for Mesh Infection After Abdominal Wall Reconstruction Incisional Hernia, Ventral Hernia | Recruiting | Minia University | 420 | 2026-08-15 | 2026-08-18 | |
| oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias Robotically-assisted ventral hernia repair (RVHR), Open ventral hernia repair (OVHR) - Ventral Hernia, Incisional Hernia | Not applicable | Recruiting | University Hospital, Basel, Switzerland | 140 | 2026-07-14 | 2026-07-24 |
| Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair AGN-151607-DP, Placebo for AGN-151607-DP - Ventral Hernia | Phase 2 | Recruiting | AbbVie | 200 | 2026-02-04 | 2026-08-25 |
| Prospective Clinical Evaluation of High-Purity Type I Collagen in Select High-Risk Hernia Repair Scenarios High-Purity Type I Collagen Mesh - Hernia, Ventral Hernia | Not applicable | Completed | Adichunchanagiri Institute of Medical Sciences, B G Nagara | 30 | 2026-01-05 | 2026-04-23 |
| Comparison of Two Plane Blocks Used in Open Ventral Hernia Repair Operations Erector Spine Plane Block, External Oblique - Intercostal Plane Block - Ventral Hernia, Postoperative Pain | Not applicable | Not yet recruiting | Ankara Ataturk Sanatorium Training and Research Hospital | 50 | 2025-09-30 | 2025-09-16 |
| AFFIX: Post-market Study of MaxTack™ Motorized Fixation Device in Subjects Undergoing Ventral Hernia Repair MaxTack™ Motorized Fixation Device - Ventral Hernia | Not applicable | Active not recruiting | Medtronic - MITG | 35 | 2025-06-16 | 2026-08-11 |
| Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia Repair Prehabilitation, Standard of Care (SOC) - Frailty, Ventral Hernia | Not applicable | Enrolling by invitation | Prisma Health-Upstate | 120 | 2025-03-19 | 2026-05-27 |
| CYP2D6 Genotype-guided Management of Opioid Analgesics in Patients Undergoing Elective Ventral Hernia Repairs Opioid pain medication prescribed based on CYP2D6 genotype testing PLUS Acetaminophen and Gabapentin, Acetaminophen and Gabapentin: standard postoperative pain medications - Ventral Hernia | Not applicable | Active not recruiting | University of Florida | 100 | 2025-01-29 | 2026-07-07 |
| Ventral Hernia Improvement of Treatment and Life Quality of life questionnair - Incisional Hernia, Parastomal Hernia | Enrolling by invitation | Line Marker | 300 | 2025-01-01 | 2025-03-21 | |
| Sublay Versus Intraperitoneal Onlay Mesh Repair in Large Ventral Hernias Ventral hernia repair - Ventral Hernia | Not applicable | Not yet recruiting | Ahmed Kahlawy Mahrous Mohamed | 50 | 2024-11-01 | 2024-10-26 |
| Investigating the Feasibility and Outcomes of Patient Self-Drain Removal After Ventral Hernia Repair Self-drain removal - Ventral Hernia | Not applicable | Terminated | Wake Forest University Health Sciences | 11 | 2024-08-19 | 2025-07-02 |
| The Impact of Abdominal Wall Reconstruction on Abdominal Wall Tension and Intra-Abdominal Pressure Abdominal wall tension, Intra-abdominal pressure - Ventral Hernia, Incisional Hernia | Terminated | The Cleveland Clinic | 2 | 2024-08-16 | 2025-09-19 | |
| ExtrAperitoneaL Plasty vs Intraperitoneal oNlay mEsh in Ventral Hernia Repair Extended totally extraperitoneal repair, Intraperitoneal onlay mesh - Ventral Hernia, Abdominal Wall Defect | Not applicable | Recruiting | University Hospital, Basel, Switzerland | 138 | 2024-07-01 | 2026-07-24 |
| A Study to Evaluate Adverse Events and Effectiveness of OnabotulinumtoxinA in Participants Undergoing Open Abdominal Ventral Hernia Repair for the Achievement of Primary Fascial Closure Without the Use of Component Separation Technique BOTOX Dose A, Placebo for BOTOX, BOTOX Dose B - Ventral Hernia, Abdominal Hernia | Phase 2 | Withdrawn | AbbVie | 2024-05-07 | 2024-05-16 |
Showing 20 of 132. Sign in to see all of them.
Hernia, Ventral (132) · Incisional Hernia (20) · Hernia (14) · Pain, Postoperative (12) · Hernia, Abdominal (10) · Hernia, Inguinal (10) · Hernia, Umbilical (10) · Postoperative Complications (5) · Pain (4) · Surgical Wound Infection (4) · Obesity (3) · Recurrence (3) · Chronic Pain (2) · Infections (2) · Seroma (2)
Pathological Conditions, Anatomical (132) · Pathological Conditions, Signs and Symptoms (132) · Hernia, Abdominal (122) · Hernia (118) · Pathologic Processes (37) · Postoperative Complications (26) · Signs and Symptoms (21) · Neurologic Manifestations (16) · Pain (12) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (10) · Infant, Newborn, Diseases (10) · Infections (5) · Body Weight (4) · Nutrition Disorders (4) · Nutritional and Metabolic Diseases (4)
Herniorrhaphy (5) · Bupivacaine (3) · Melanocyte-Stimulating Hormones (3) · Acetaminophen (2) · Gabapentin (2) · Preoperative Exercise (2) · Robotic Surgical Procedures (2) · Biological Products (1) · Botulinum Toxins, Type A (1) · Diet (1) · Drainage (1) · Ethanol (1) · Exercise (1) · Fentanyl (1) · Fibrin Tissue Adhesive (1)
Zealand University Hospital (7) · The Cleveland Clinic (6) · Assiut University (5) · Medtronic - MITG (5) · University Hospital, Ghent (5) · Prisma Health-Upstate (4) · Wake Forest University Health Sciences (4) · Algemeen Ziekenhuis Maria Middelares (3) · C. R. Bard (3) · Intuitive Surgical (3) · Northwestern University (3) · The University of Texas Health Science Center, Houston (3) · University of Florida (3) · AbbVie (2) · Bispebjerg Hospital (2)
United States (60) · Belgium (11) · Denmark (11) · Egypt (6) · Switzerland (5) · Canada (4) · France (4) · Sweden (4) · Turkey (Türkiye) (3) · United Kingdom (3) · India (2) · Israel (2) · Spain (2) · Austria (1) · Brazil (1)
Frederik Berrevoet, MD (3) · Frederik Helgstrand, MD (3) · Ajita Prabhu, MD (2) · Brant T Heniford, MD (2) · Dunja Kokotovic, MS (2) · Filip Muysoms, MD (2) · Iris Kyle-Leinhase, PhD (2) · Jeremy A Warren, MD (2) · Johannes Baur, MD (2) · Saleh K Saleh, MD (2) · Stijn De Sutter, MD (2) · Todd Heniford, MD (2) · Adam Young, MD (1)
PMID 20033726, PMID 20395855, PMID 21964681, PMID 21975153, PMID 22580941, PMID 22797701, PMID 23095614, PMID 23756775, PMID 23782773, PMID 24374547, PMID 26021417, PMID 26037907, PMID 26206644, PMID 28438090, PMID 28916979, PMID 29247365, PMID 29799075, PMID 30772851, PMID 32228664, PMID 32368702, PMID 33084881, PMID 34116953, PMID 34524395, PMID 34905143, PMID 35044431, PMID 35588504, PMID 35703814, PMID 36102523, PMID 37310015, PMID 37342018, PMID 38811911, PMID 38890182, PMID 40035894, PMID 40435308, PMID 40792628, PMID 41032176, PMID 42170404
1KM1CA156708-01 (1), 2019 (1), 2023 (1), R01DK131207 (1), UL1TR001427 (1)