6 completed, 3 unknown, 2 recruiting, 1 suspended. 5 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Recruiting 2, Unknown 2, Completed 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Ventilation Perfusion Mismatch: new trials by email Literature Review of Ventilation Perfusion Mismatch trials Research Report on Ventilation Perfusion Mismatch
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ventilator Pressure and Optimization of Compliance and Hemodynamics Increase in the PEEP followed by decrease in the PEEP, Decrease in the PEEP followed by increase in the PEEP - Bronchopulmonary Dysplasia, Pulmonary Hypertension Due to Lung Diseases and Hypoxia | Not applicable | Recruiting | University of Alabama at Birmingham | 24 | 2026-08-01 | 2026-05-11 |
| Vascular ARDS Recruitment After Inhaled Nitric Oxide Nitric Oxide - Acute Respiratory Distress Syndrome, Ventilation Perfusion Mismatch | Not applicable | Recruiting | Massachusetts General Hospital | 70 | 2026-07-10 | 2026-10-02 |
| Positional Effects on Lung Ventilation and Perfusion in Obesity Standardized body positioning - Obesity (Disorder), Ventilation Homogeneity | Completed | Koç University | 40 | 2025-12-01 | 2026-04-15 | |
| Post-hoc Analysis of Regional Pulmonary Perfusion and Hemodynamic Parameters Measured by Electrical Impedance Tomography PulmoVista 500 - Mechanical Ventilation, Ventilation Perfusion Mismatch | Suspended | Drägerwerk AG & Co. KGaA | 22 | 2024-01-01 | 2023-03-06 | |
| Evaluate the Effect of Prone Ventilation on Ventilated-blood Flow Ratio in Patients With ARDS by EIT Acute Respiratory Distress Syndrome, Electrical Impedance Tomography | Completed | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 94 | 2023-12-30 | 2025-09-09 | |
| 68Ga PET/CT Versus 99mTc SPECT/CT for Lung Perfusion and Ventilation Scintigraphy; a Technical and Practical Feasibility Study Ga-68 V/Q PET/CT - Pulmonary Embolism, Ventilation Perfusion Mismatch | Not applicable | Unknown | UMC Utrecht | 20 | 2023-03-01 | 2024-02-09 |
| Change in the Phase III Slope of the Volumetric Capnography by Prone Positioning in Acute Respiratory Distress Syndrome Prone Positioning - Acute Respiratory Distress Syndrome, Ventilation Perfusion Mismatch | Unknown | Istanbul University - Cerrahpasa | 60 | 2022-09-06 | 2024-07-03 | |
| Arterial and End-Tidal CO2 Gradient as a Mortality Predictor in Critical Care Patients EtCO2, PaCO2 - Critical Illness, Ventilation Perfusion Mismatch | Not applicable | Completed | Gaziosmanpasa Research and Education Hospital | 50 | 2022-01-01 | 2022-08-24 |
| Nebulised Heparin to Reduce COVID-19 Induced Acute Lung Injury Nebulised heparin - Covid19, ARDS, Human | Phase 1 / Phase 2 | Completed | University College Hospital Galway | 40 | 2020-12-23 | 2024-07-24 |
| Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients Extravascular Lung Water Index, Pulmonary Vascular Permeability Index - Respiratory Distress Syndrome, Adult, Ventilation Perfusion Mismatch | Withdrawn | Istanbul University - Cerrahpasa | 2020-09-01 | 2021-10-26 | ||
| Prone Position Improves End-Expiratory Lung Volumes in COVID-19 Acute Respiratory Distress Syndrome Acute Respiratory Distress Syndrome, Coronavirus | Completed | Istanbul University - Cerrahpasa | 43 | 2020-09-01 | 2022-03-04 | |
| Effect of Patient Position on Arterial, End-tidal and Transcutaneous Carbon Dioxide Arterial carbon dioxide monitoring, End-tidal carbon dioxide monitoring, Transcutaneous carbon dioxide monitoring - Ventilation Perfusion Mismatch | Not applicable | Unknown | SMG-SNU Boramae Medical Center | 142 | 2018-05-20 | 2018-05-01 |
| Effect of Alveolar Minute Ventilation on Respiratory Gas Heat Content controlled positive pressure ventilation 9ml/kg tidal volume, controlled positive pressure ventilation 6ml/kg tidal volume - Ventilation Perfusion Mismatch | Completed | University of California, Davis | 20 | 2013-08-01 | 2019-10-28 |
Respiratory Distress Syndrome (7) · Acute Lung Injury (2) · COVID-19 (2) · Pulmonary Embolism (2) · Bronchopulmonary Dysplasia (1) · Coronavirus Infections (1) · Critical Illness (1) · Hypoxia (1) · Obesity (1) · Pulmonary Disease, Chronic Obstructive (1) · Pulmonary Edema (1) · Respiratory Aspiration (1) · Respiratory Insufficiency (1) · Shock (1) · Wounds and Injuries (1)
Lung Diseases (9) · Respiratory Tract Diseases (9) · Respiration Disorders (7) · Pathological Conditions, Signs and Symptoms (4) · Coronaviridae Infections (3) · Infections (3) · Lung Injury (3) · Nidovirales Infections (3) · RNA Virus Infections (3) · Virus Diseases (3) · Cardiovascular Diseases (2) · Coronavirus Infections (2) · Embolism (2) · Embolism and Thrombosis (2) · Pathologic Processes (2)
Blood Gas Monitoring, Transcutaneous (1) · Fractional Exhaled Nitric Oxide Testing (1) · Prone Position (1) · Tidal Volume (1)
Istanbul University - Cerrahpasa (3) · Drägerwerk AG & Co. KGaA (1) · Gaziosmanpasa Research and Education Hospital (1) · Koç University (1) · Massachusetts General Hospital (1) · SMG-SNU Boramae Medical Center (1) · UMC Utrecht (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University College Hospital Galway (1) · University of Alabama at Birmingham (1) · University of California, Davis (1)
Turkey (Türkiye) (5) · United States (3) · China (1) · Germany (1) · Ireland (1) · Netherlands (1)
Colm P Travers, MD (1) · John Laffey (1) · Kulsajan S Bhatia, MD (1) · Maurizio Cereda, MD (1) · Michael Quintel, Prof. Dr. (1) · Neal Fleming, MD, PhD (1) · Olcay Dilken, Dr. (1) · Olcay Dilken, MD (1) · Ulku Aygen Turkmen, Proffessor (1)
PMID 28625165, PMID 32859359, PMID 32876469, PMID 33196303, PMID 36104785, PMID 36530873, PMID 41862829