12 completed, 6 unknown, 3 not yet recruiting. 19 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 19 | Completed 11, Unknown 6, Not yet recruiting 2 |
Follow Tidal Volume: new trials by email Literature Review of Tidal Volume trials Research Report on Tidal Volume
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mechanical Ventilator Adjustments and Patient Dyspnea Change to VC/AC, Change in Tidal Volume, Change in inspiratory flow - Respiratory Failure, Dyspnea During Mechanical Ventilation | Not applicable | Not yet recruiting | Beth Israel Deaconess Medical Center | 20 | 2026-09-01 | 2026-07-14 |
| Exploring Perceptual Learning in Blurred Gabor Discrimination for Low-Myopic Children vision training system, VTS - Myopia, Visual Rehabilitation | Not applicable | Not yet recruiting | National Taiwan University Hospital | 30 | 2026-09-01 | 2026-08-14 |
| Validation of an Effort-Based Cough Peak Flow Algorithm to Predict Extubation Outcomes Observational measurement of Cough Peak Flow and Tidal Volume - Extubation Failure | Not yet recruiting | Hospital H+ Queretaro | 150 | 2026-07-01 | 2026-07-30 | |
| Susceptibility for Entrainment: Role of Ventilator Settings on the Occurrence of Reverse Triggering and Its Physiological Consequences - the SEVeRe Study Changes in the ventilator respiratory rate and tidal volume - Respiration, Artificial, Reverse Triggering | Not applicable | Unknown | Unity Health Toronto | 30 | 2025-01-30 | 2025-05-20 |
| Intra-Operative Modified Ventilator Mechanical Power in Laparoscopic Bariatric Surgeries Group I ( volume-controlled ventilation with tidal volume 6-8ml/kg (predicted body weight) with respiratory rate 12-14 cycle/minute., Group II: (volume-controlled ventilation with tidal volume 6-8ml/kg ) - Laparoscopic Bariatric Surgeries, Hypoxemia | Not applicable | Completed | Tanta University | 100 | 2023-11-30 | 2025-07-15 |
| Respiratory and Hemodynamic Targets During General Anesthesia Blood pressure, Positive end expiratory pressure, Tidal volume - Patients Undergoing General Anesthesia | Not applicable | Completed | Lars Wiuff Andersen | 485 | 2023-10-09 | 2025-08-05 |
| Impact of Chest Wall Mechanics on Lung and Cardiovascular Function During Delayed Sternal Closure Esophageal manometry catheter at various PEEP levels and tidal volumes - Palliation of Congenital Heart Diseases, Cardiopulmonary Bypass | Not applicable | Completed | The Hospital for Sick Children | 10 | 2022-08-26 | 2025-07-16 |
| Effect of Low Tidal Ventilation on Intraoperative Bleeding in Laparoscopic Major Hepatectomy conventional tidal volume (tidal volume [ml]= ideal body weight [kg]* 10~12) group, low tidal (tidal volume [ml]= ideal body weight [kg] * 6~8) volume - Ventilator Lung, Liver Cirrhosis | Not applicable | Unknown | Seoul National University Hospital | 58 | 2022-08-08 | 2022-08-05 |
| Plethysmography Curve Variability Depending on the Breath Cycle Respiratory rate, Tidal volume, Apnea - Apnea, Circulatory; Change | Not applicable | Completed | Czech Technical University in Prague | 10 | 2022-03-10 | 2025-03-25 |
| The Effect of 6 ml/kg vs 10 ml/kg Tidal Volume on Diaphragm Dysfunction in Critically Mechanically Ventilated Patient Tidal volume 6 ml/kg, Tidal volume 10 ml/kg - Mechanical Ventilation Complication | Not applicable | Unknown | Dr Cipto Mangunkusumo General Hospital | 44 | 2021-09-01 | 2022-05-11 |
| Exploration of the Appropriate Combination of Positive End Expiratory Pressure and Tidal Volume Using the Intratidal Compliance Volume Profile in Children Changes in positive end-expiratory pressure and tidal volume - Respiratory Compliance | Not applicable | Completed | Seoul National University Hospital | 43 | 2020-12-02 | 2022-05-05 |
| ETT Cuff Leak: TV Ratios CPAP, Tidal volume - Surgical Procedures, Operative | Not applicable | Completed | Nationwide Children's Hospital | 50 | 2020-08-17 | 2024-06-21 |
| Effects of Two Different Stepwise Lung Recruitment Maneuvers on Patient Hemodynamics During Laproscopic Surgery Recruitment maneuver with tidal volume (RM TV), Recruitment maneuver by PEEP (RM PEEP) - Recruitment | Not applicable | Completed | Mansoura University | 80 | 2019-09-05 | 2021-10-14 |
| Effect of Low Tidal Volume on Blood Loss During Laparoscopic Hepatectomy Tidal volume - Blood Loss | Not applicable | Unknown | Southwest Hospital, China | 104 | 2017-04-01 | 2018-01-16 |
| Comparison of Ventilation Distribution Between Tidal Volume 6ml/kgBW and 10ml/kgBW Tidal volume 6 ml/kgBW, Tidal volume 10 ml/kgBW - Laparoscopic Nephrectomy | Not applicable | Completed | Universitas Indonesia | 30 | 2016-05-01 | 2017-08-18 |
| Study of Respiratory Physiology During High Flow Nasal Cannula Treatment in Preterm Neonates. Pharyngeal pressure, Transcutaneous carbon dioxide, Pharyngeal gas concentrations - Extreme Prematurity - Less Than 28 Weeks, Respiratory Distress Syndrome in Premature Infants | Not applicable | Unknown | Newcastle-upon-Tyne Hospitals NHS Trust | 45 | 2014-08-01 | 2014-07-25 |
| EPO2-PV: Evaluation of Pre-Oxygenation Conditions in Morbidly Obese Volunteer: Effect of Position and Ventilation Mode NIPPV, Tidal volume - Morbid Obesity, Bariatric Surgery Candidate | Not applicable | Completed | Laval University | 20 | 2014-04-01 | 2018-04-09 |
| Comparison of Two Ventilation Modes With Laryngeal Mask Airway Guardian tidal volume, peak airway pressure - Gynecologic Disease | Not applicable | Unknown | Haiyun Wang | 40 | 2014-04-01 | 2014-03-27 |
| Effect of Alveolar Minute Ventilation on Respiratory Gas Heat Content controlled positive pressure ventilation 9ml/kg tidal volume, controlled positive pressure ventilation 6ml/kg tidal volume - Ventilation Perfusion Mismatch | Completed | University of California, Davis | 20 | 2013-08-01 | 2019-10-28 | |
| Effects of Increased Tidal Volume on Internal Jugular Vein Cross-sectional Area Tidal Volume - General Anesthesia, Surgery | Not applicable | Completed | Yonsei University | 40 | 2010-07-01 | 2011-04-19 |
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Respiratory Aspiration (3) · Apnea (1) · Blood Loss, Surgical (1) · Carcinoma, Hepatocellular (1) · Dyspnea (1) · Genital Diseases, Female (1) · Heart Defects, Congenital (1) · Hemorrhage (1) · Hypoxia (1) · Liver Cirrhosis (1) · Lung Neoplasms (1) · Myopia (1) · Obesity, Morbid (1) · Postoperative Complications (1) · Respiratory Distress Syndrome In Premature Infants (1)
Seoul National University Hospital (2) · Assistance Publique - Hôpitaux de Paris (1) · Beth Israel Deaconess Medical Center (1) · Czech Technical University in Prague (1) · Dr Cipto Mangunkusumo General Hospital (1) · Haiyun Wang (1) · Hospital H+ Queretaro (1) · Lars Wiuff Andersen (1) · Laval University (1) · Mansoura University (1) · National Taiwan University Hospital (1) · Nationwide Children's Hospital (1) · Newcastle-upon-Tyne Hospitals NHS Trust (1) · Southwest Hospital, China (1) · Tanta University (1)
Canada (3) · South Korea (3) · United States (3) · Egypt (2) · Indonesia (2) · China (1) · Czechia (1) · Denmark (1) · France (1) · Taiwan (1) · United Kingdom (1)
Ahmed Elbradey, Resident (1) · Christopher O'Brien, MRCP, FRCPCH (1) · Dita Aditianingsih, Consultant (1) · Dita Aditianingsih, Dr (1) · Elias Baedorf-Kassis, MD (1) · Emmanuel Marret, MD (1) · Etienne J Couture, MD (1) · Haiyun Wang, M.D.Ph.D. (1) · Jakub Rafl, PhD (1) · Laurent Brochard (1) · Luciana Rodriguez Guerineau, MD (1) · Mahmoud M Othman, MD (1) · Neal Fleming, MD, PhD (1) · Richard Schwartzstein, MD (1)
PMID 29435810, PMID 29561278, PMID 34686309, PMID 40913357, PMID 42508987, PMID 42578528