81 completed, 29 terminated, 16 unknown, 8 withdrawn. 48 Not applicable, 41 Phase 3, 21 Phase 2, 11 Phase 4, 7 Phase 1.
Follow Uterine Fibroids: new trials by email Literature Review of Uterine Fibroids trials Research Report on Uterine Fibroids
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prospective Perioperative Clinical Registry for Women Undergoing Benign Gynecological Surgery Standard Surgical Procedures for Benign Gynecological Conditions - Benign Gynecological Disease, Uterine Fibroids | Not yet recruiting | IRCCS San Raffaele | 6000 | 2026-09-01 | 2026-08-19 | |
| Single-channel Fibroid Morcellation System Used in Clinical Research on Laparoscopic Myomectomy Single-channel specimen retrieval bag, Double-channel specimen retrieval bag - Uterine Fibroids | Not applicable | Not yet recruiting | First People's Hospital of Hangzhou | 78 | 2026-05-01 | 2026-04-06 |
| Transmucosal Uterosacral Electrical Stimulation for Pelvic Pain Relief TUNES (Transmucosal Uterosacral Electrical Stimulation), Sham TUNES Device - Postoperative Pain After Uterine Fibroid Embolization, Uterine Fibroids (UF) | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 60 | 2026-04-01 | 2026-03-30 |
| Predictors of Success and Failure of v-NOTES Hysterectomy for Large and Very Large Uteri Uterine Fibroids, Hysterectomy | Recruiting | University Hospital, Strasbourg, France | 50 | 2026-03-20 | 2026-10-26 | |
| to Evaluate the Efficacy and Safety of KLH-2109 in Patients With Uterine Fibroids and Menorrhagia KLH-2109+ Leurprorelin acetate Placebo, KLH-2109 Placebo + Leurprorelin acetate - Menorrhagia, Uterine Fibroids | Phase 3 | Recruiting | JW Pharmaceutical | 254 | 2026-02-03 | 2026-05-01 |
| Prospective Validation Study of a Uterine Fibroid-Related Infertility Prediction Model No intervention - Uterine Fibroids, Female Infertility | Not yet recruiting | Tongji Hospital | 7084 | 2025-09-30 | 2025-09-17 | |
| An Open-Label Study to Evaluate the Effect of Elix Cycle Balance & Elix Daily Harmony on Fibroid-related Symptoms Elix Daily Harmony - Uterine Fibroids, Leiomyoma | Not applicable | Recruiting | Zenchi, Inc. | 42 | 2025-08-01 | 2025-09-12 |
| Anterior Quadratus Lumborum Block as a Component of Multimodal Analgesia for Abdominal Hysterectomies ANTERİOR QUADRATUS LUMBORUM BLOCK, Parenteral administration of analgesics, General Anesthesia (GA) - Uterine Bleeding, Uterine Neoplasms | Not applicable | Completed | Yuri Semenyuk Rivne Regional Clinical Hospital | 56 | 2025-07-07 | 2025-12-16 |
| Use of Nitrous Oxide During Office Hysteroscopy Inhalation of Nitrous Oxide (N₂O) during Office Operative Hysteroscopy, inhalation of ambient air during office hysteroscopy - Abnormal Uterine Bleeding, Postmenopausal Bleeding | Not applicable | Active not recruiting | Maaynei Hayesha Medical Center | 400 | 2025-07-01 | 2025-07-20 |
| A Trial of SHR7280 in Healthy Subjects SHR7280 Tablet, SHR7280 Placebo Tablet - Endometriosis, Uterine Fibroids | Phase 1 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 16 | 2025-05-19 | 2025-08-19 |
| A Phase 1 Clinical Study to Evaluate the Effects of SHR7280 on the Pharmacokinetics of Midazolam, S-warfarin, Omeprazole, Digoxin, and Rosuvastatin in Healthy Subjects SHR7280 Tablets - Endometriosis, Uterine Fibroids | Phase 1 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 20 | 2025-04-28 | 2025-09-10 |
| A Clinical Study on the Feasibility and Safety of Abdominal Endoscopic Single-port Surgery System to Assist Gynecological Day Surgery Domestic single-port laparoscopic surgery system - Adenopathy, Uterine Fibroids | Not applicable | Not yet recruiting | Second Affiliated Hospital of Wenzhou Medical University | 63 | 2025-04-10 | 2025-04-03 |
| Transvaginal Electromechanical Fragmentation and Removal of Large Uterus in a Sealed Bag: The First Group of Clinical Studies Balancing Scar - Free and Anti - Dissemination Uterine Fibroids, Adenomyosis | Active not recruiting | Chang Zhou | 25 | 2025-03-01 | 2026-03-20 | |
| Preoperative Administration of EGCG, Vitamin D and DCI Prior Hysteroscopic Myomectomy Hysteroscopic myomectomy - Uterine Fibroids, Hysteroscopic Myomectomy | Completed | Centro di Ricerca Clinica Salentino | 90 | 2025-02-01 | 2025-12-04 | |
| Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids Relugolix, Relugolix placebo - Heavy Menstrual Bleeding, Uterine Fibroids | Phase 3 | Recruiting | Qilu Pharmaceutical Co., Ltd. | 120 | 2024-01-15 | 2026-02-02 |
| Study on Vaginal Microecology and Cervical Local Immune Function in Patients With Uterine Fibroids of Childbearing Age Microscopic examination of vaginal discharge - Uterine Fibroids | Unknown | Lin Yuan | 300 | 2023-10-09 | 2023-09-26 | |
| A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis Relugolix Combination Tablet - Uterine Fibroids, Endometriosis | Phase 3 | Recruiting | Sumitomo Pharma Switzerland GmbH | 1000 | 2023-08-14 | 2025-08-06 |
| Efficacy and Safety of BG2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids. BG2109, Placebo for BG2109, Placebo for add-back therapy - Uterine Fibroids, Heavy Menstrual Bleeding | Phase 3 | Unknown | Bio Genuine (Shanghai) Biotech Co., Ltd. | 312 | 2022-12-16 | 2023-03-21 |
| Vitamin D, Epigallocatechin Gallate, D-chiro-inositol and Vitamin B6 in Uterine Fibroid Epigallocatechin gallate, Vitamin D, Vitamin B6, D-chiro-inositol, Placebo - Uterine Fibroids, D-chiro-inositol | Not applicable | Recruiting | Lo.Li.Pharma s.r.l | 60 | 2022-07-01 | 2026-02-12 |
| Effect of Addition of Steroids on Duration of Analgesia Triamcinolone, Bupivacaine, Iohexol contrast - Uterine Fibroids, Adenomyosis | Early Phase 1 | Active not recruiting | University of California, Los Angeles | 28 | 2022-01-06 | 2025-12-17 |
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Leiomyoma (150) · Menorrhagia (34) · Myofibroma (14) · Adenomyosis (9) · Metrorrhagia (8) · Endometriosis (7) · Pelvic Pain (7) · Agnosia (6) · Uterine Hemorrhage (6) · Myoma (5) · Polyps (4) · Uterine Neoplasms (4) · Neoplasms (3) · Ovarian Cysts (3) · Anemia (2)
Neoplasms by Histologic Type (150) · Neoplasms, Connective and Soft Tissue (150) · Neoplasms, Muscle Tissue (150) · Neoplasms (147) · Urogenital Diseases (57) · Female Urogenital Diseases (56) · Female Urogenital Diseases and Pregnancy Complications (56) · Genital Diseases (56) · Pathological Conditions, Signs and Symptoms (56) · Genital Diseases, Female (54) · Pathologic Processes (46) · Uterine Diseases (46) · Hemorrhage (40) · Menstruation Disturbances (35) · Uterine Hemorrhage (34)
telapristone acetate (17) · elagolix (7) · Uterine Myomectomy (6) · estradiol, norethindrone drug combination (6) · relugolix (6) · vilaprisan (6) · Estradiol (5) · Norethindrone Acetate (5) · Uterine Artery Embolization (5) · ulipristal acetate (5) · asoprisnil (4) · Leuprolide (3) · Mifepristone (3) · Sugars (3) · Letrozole (2)
Repros Therapeutics Inc. (17) · AbbVie (7) · InSightec (7) · Bayer (6) · PregLem SA (6) · Gynesonics (5) · Abbott (4) · Acessa Health, Inc. (4) · Philips Healthcare (4) · Takeda (4) · University of California, San Francisco (4) · Boston Scientific Corporation (3) · Ethicon, Inc. (3) · Hologic, Inc. (3) · Mediterranea Medica S. L. (3)
United States (66) · Italy (13) · United Kingdom (12) · China (11) · Canada (10) · France (10) · Germany (10) · Netherlands (9) · Poland (9) · Czechia (8) · Spain (8) · Austria (7) · Mexico (7) · Belgium (6) · Hungary (6)
Anna Chan (4) · Vanessa Jacoby, MD (4) · Andre van As, MD, PhD (3) · David Toub, MD (3) · Fulvio Zullo (3) · George Holland, M.D. (3) · Ahunna Ukah (2) · Anne Roberts, M.D. (2) · Elizabeth A. Stewart, M.D. (2) · Mark Shaman, M.D. (2)
PMID 34878624, PMID 24630081, PMID 31971678, PMID 33650259, PMID 34553161, PMID 34582715, PMID 36116480, PMID 39381651, PMID 40326221, PMID 40543832, PMID 17197583, PMID 17339234, PMID 18579510, PMID 19389793, PMID 21545960, PMID 21794858, PMID 22626269, PMID 23073229, PMID 23635746, PMID 23941588, PMID 23984082, PMID 24018147, PMID 24021910, PMID 24324590, PMID 24356165, PMID 24613404, PMID 24698202, PMID 24788209, PMID 24841647, PMID 24981461, PMID 25542821, PMID 25634727, PMID 25989973, PMID 26097247, PMID 26335129, PMID 26471917, PMID 26477496, PMID 26658133, PMID 26892690, PMID 27073063, PMID 27733082, PMID 27822376, PMID 28063909, PMID 28676450, PMID 28796688, PMID 29100237, PMID 29139105, PMID 29177589, PMID 29890128, PMID 30012030
2016 (3), 1RC1HD063312-01 (1), 2005 (1), 2017 (1), 2018 (1), R01HD100369 (1), R21HD091337 (1)