7 completed, 2 unknown, 1 terminated, 1 withdrawn. 11 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 7, Unknown 2, Terminated 1, Withdrawn 1 |
Follow Uterine Fibroids: new trials by email Literature Review of Uterine Fibroids trials Research Report on Uterine Fibroids
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Safety and Efficacy of Elagolix for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women Elagolix, Placebo - Uterine Fibroids | Phase 4 | Completed | AbbVie | 82 | 2019-04-12 | 2022-03-31 |
| Efficacy and Safety of Rapamycin (Sirolimus) in the Treatment of Symptomatic Uterine Fibroids and Leiomyomatosis rapamycin - Uterine Fibroids | Phase 4 | Unknown | Peking Union Medical College Hospital | 25 | 2018-01-01 | 2018-04-18 |
| Treatment of Heavy Menstrual Bleeding in Women With Uterine Fibroids Levonorgestrel IUS, Tranexamic Acid - Heavy Menstrual Bleeding, Menorrhagia | Phase 4 | Completed | Shannon K. Laughlin-Tommaso | 18 | 2017-11-14 | 2021-12-08 |
| Endometrial Preparation Before Operative Hysteroscopy in Premenopausal Women operative hysteroscopy, Dienogest, Ulipristal acetate - Uterine Fibroids | Phase 4 | Unknown | University of Cagliari | 50 | 2016-06-01 | 2016-03-09 |
| Pilot of Letrozole for Uterine Myomas Letrozole, Placebo - Leiomyoma, Uterine Fibroids | Phase 4 | Completed | University of California, San Francisco | 12 | 2015-07-01 | 2019-11-15 |
| Preemptive Analgesia Following Uterine Artery Embolization pregabalin/celecoxib, pregabalin/placebo, celecoxib/placebo - Uterine Fibroids, Uterine Artery Embolization | Phase 4 | Terminated | Northwestern University | 23 | 2011-10-01 | 2016-07-28 |
| The FIRSTT: Comparing MRgFUS(MR-guided Focused Ultrasound) Versus UAE (Uterine Artery Embolization)for Uterine Fibroids. Focused ultrasound (MRgFUS), Uterine artery embolization (UAE) - Symptomatic Uterine Leiomyomas, Fibroids | Phase 4 | Completed | Mayo Clinic | 56 | 2010-04-29 | 2018-01-12 |
| Efficacity Assessment of PREVADH® in Adhesion Prevention in Gynaecologic Surgery Ringer lactate solution, Prevadh film - Uterine Fibroids, Fertility Disorders | Phase 4 | Completed | Medtronic - MITG | 61 | 2006-05-01 | 2016-11-17 |
| A Prospective Study Comparing Contour SE™ Microspheres to Embosphere® Microspheres for Treating Symptomatic Uterine Fibroids With Uterine Fibroid Embolization (UFE) Uterine Fibroid Embolization (UFE), Contour SE™ Microspheres, Embosphere® Microspheres - Leiomyoma, Uterine Fibroids | Phase 4 | Completed | Boston Scientific Corporation | 60 | 2006-01-01 | 2012-07-11 |
| Safety Trial of Magnetic Resonance (MR) Guided Focused Ultrasound Surgery (FUS) in Women With Uterine Fibroids Wishing to Pursue Pregnancy in the Future Magnetic Resonance Guided Focused Ultrasound - Uterine Fibroids, Pregnancy | Phase 4 | Withdrawn | Imperial College London | 2004-04-01 | 2023-10-24 | |
| Efficacy Study of Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Large Fibroids Magnetic Resonance Guided Focused Ultrasound - Uterine Fibroids | Phase 4 | Completed | Imperial College London | 50 | 2003-03-01 | 2008-08-13 |
Leiomyoma (11) · Menorrhagia (3) · Leiomyomatosis (1) · Myofibroma (1) · Myoma (1) · Pelvic Pain (1) · Uterine Neoplasms (1)
Neoplasms (11) · Neoplasms by Histologic Type (11) · Neoplasms, Connective and Soft Tissue (11) · Neoplasms, Muscle Tissue (11) · Pathological Conditions, Signs and Symptoms (4) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Genital Diseases (3) · Genital Diseases, Female (3) · Hemorrhage (3) · Menstruation Disturbances (3) · Pathologic Processes (3) · Urogenital Diseases (3) · Uterine Diseases (3) · Uterine Hemorrhage (3)
Celecoxib (1) · Letrozole (1) · Pregabalin (1) · Sirolimus (1) · Tranexamic Acid (1) · Uterine Artery Embolization (1) · dienogest (1) · elagolix (1) · ulipristal acetate (1)
Imperial College London (2) · AbbVie (1) · Boston Scientific Corporation (1) · Mayo Clinic (1) · Medtronic - MITG (1) · Northwestern University (1) · Peking Union Medical College Hospital (1) · Shannon K. Laughlin-Tommaso (1) · University of Cagliari (1) · University of California, San Francisco (1)
United States (6) · United Kingdom (2) · China (1) · France (1) · Puerto Rico (1)
Christopher C Destephano, MD, MPH (1) · Elizabeth A. Stewart, M.D. (1) · Lan Zhu, MD (1) · Pamela Grady, Ph.D (1) · Richard Shalansky-Goldberg, MD (1) · Shannon K Laughlin-Tommaso, MD, MPH (1) · Vanessa Jacoby, MD (1) · Wady Gedroyc (1)
PMID 21794858, PMID 24788209, PMID 24841647, PMID 25989973, PMID 27073063, PMID 28063909, PMID 30696556, PMID 34242085, PMID 37769311, PMID 38481209
1RC1HD063312-01 (1), R21HD091337 (1)