6 completed, 1 unknown. 7 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 6, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Uterine Fibroids: new trials by email Literature Review of Uterine Fibroids trials Research Report on Uterine Fibroids
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial of SHR7280 in Healthy Subjects SHR7280 Tablet, SHR7280 Placebo Tablet - Endometriosis, Uterine Fibroids | Phase 1 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 16 | 2025-05-19 | 2025-08-19 |
| A Phase 1 Clinical Study to Evaluate the Effects of SHR7280 on the Pharmacokinetics of Midazolam, S-warfarin, Omeprazole, Digoxin, and Rosuvastatin in Healthy Subjects SHR7280 Tablets - Endometriosis, Uterine Fibroids | Phase 1 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 20 | 2025-04-28 | 2025-09-10 |
| Pharmacokinetics and Hepatic Safety of EGCG Epigallocatechin gallate (EGCG), Clomiphene Citrate, Letrozole - Uterine Fibroids | Phase 1 | Completed | Yale University | 39 | 2020-11-24 | 2023-06-05 |
| Pharmacokinetics and Safety of Vilaprisan in Renal Impairment Vilaprisan (BAY1002670) - Uterine Fibroids, Endometriosis | Phase 1 | Completed | Bayer | 26 | 2018-02-02 | 2019-12-03 |
| Clinical Test of the MRgHIFU System on Uterine Fibroids MRgHIFU system - Uterine Fibroids | Phase 1 | Unknown | Chin-Jung Wang | 20 | 2014-09-01 | 2014-11-05 |
| Pilot Study of MRI-Guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids Philips MR guided HIFU system - Uterine Fibroids, Uterine Leiomyomata | Phase 1 / Phase 2 | Completed | Philips Healthcare | 11 | 2009-01-01 | 2012-12-04 |
| The Effect of Mifepristone on Uterine Fibroids and Breast Tissue Mifegyne, placebo - Uterine Fibroids | Phase 1 | Completed | Karolinska Institutet | 30 | 2004-11-01 | 2015-05-25 |
Leiomyoma (7) · Endometriosis (3) · Myofibroma (1)
Neoplasms (7) · Neoplasms by Histologic Type (7) · Neoplasms, Connective and Soft Tissue (7) · Neoplasms, Muscle Tissue (7) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Genital Diseases (3) · Genital Diseases, Female (3) · Urogenital Diseases (3) · Connective Tissue Diseases (1) · Neoplasms, Connective Tissue (1) · Skin and Connective Tissue Diseases (1)
Clomiphene (1) · Letrozole (1) · Mifepristone (1) · epigallocatechin gallate (1) · vilaprisan (1)
Jiangsu HengRui Medicine Co., Ltd. (2) · Bayer (1) · Chin-Jung Wang (1) · Karolinska Institutet (1) · Philips Healthcare (1) · Yale University (1)
United States (3) · China (2) · Sweden (1) · Taiwan (1)
Ayman Al-Hendy, MD,PhD (1) · Chin-Jung Wang, MD (1) · Esther Eisenberg, MD (1) · Frank Gonzales, MD (1) · Heping Zhang, PhD (1) · Hugh Taylor, MD (1) · James Segars, MD (1) · Kristina Gemzell Danielsson, Prof.MD.PHD (1)
PMID 18579510, PMID 19389793, PMID 22626269, PMID 24324590, PMID 25634727, PMID 29890128, PMID 40077973
R01HD100369 (1)