12 completed, 3 not yet recruiting, 3 withdrawn, 2 recruiting. 11 Phase 4, 4 Not applicable, 2 Phase 2, 1 Early Phase 1, 1 Phase 1.
Follow Uterine Atony: new trials by email Literature Review of Uterine Atony trials Research Report on Uterine Atony
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority Trial Carbetocin, Oxytocin, Placebo Saline Infusion - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Recruiting | Mansoura University | 332 | 2026-08-08 | 2026-10-09 |
| Oxytocin Bolus Versus Infusion in High-Risk Patients Undergoing Elective Cesarean Section (INBOX-HR) Oxytocin Bolus or Oxytocin Infusion - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Not yet recruiting | Stony Brook University | 180 | 2026-08-01 | 2026-08-03 |
| Balloon Tamponade Versus Gauze Packing for Postpartum Hemorrhage Uterine Balloon Tamponade, Uterine gauze packing - Postpartum Hemorrhage, Uterine Atony | Not applicable | Not yet recruiting | Khyber Teaching Hospital | 216 | 2026-07-01 | 2026-05-27 |
| Exteriorization Versus In Situ Hysterotomy Repair During Cesarean: Effects on Uterine Tone Test Intervention: In Situ Repair, Comparator Intervention: Exteriorization - Postpartum Hemorrhage, Uterine Atony | Not applicable | Not yet recruiting | Stanford University | 60 | 2026-06-01 | 2026-05-27 |
| Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine Atony Calcium Gluconate, Saline - Blood Loss, Surgical, Blood Loss, Postoperative | Phase 2 | Recruiting | University of Michigan | 140 | 2025-10-20 | 2026-07-24 |
| Placental Removal Method And Uterine Massage On Preventing Postpartum Hemorrhage Manual Removal 1, Manual Removal 2, Controlled Cord Traction 1 - Postpartum Hemorrhage, Cesarean Section Complications | Completed | Busra Lekesiz | 361 | 2024-01-10 | 2026-07-15 | |
| Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery Calcium chloride, Saline placebo - Uterine Atony, Uterine Atony With Hemorrhage | Phase 3 | Completed | Stanford University | 120 | 2022-04-04 | 2024-06-11 |
| Intravenous Versus Intramuscular Administration of Methylergonovine for Uterine Contraction in Cesarean Sections Methylergonovine - Uterine Atony, Uterine Tone Disorders | Early Phase 1 | Withdrawn | Johns Hopkins University | 2020-07-01 | 2020-08-03 | |
| Calcium Chloride for Prevention of Uterine Atony During Cesarean Calcium Chloride, Placebo - Uterine Atony, Uterine Atony With Hemorrhage | Phase 1 / Phase 2 | Completed | Stanford University | 40 | 2019-03-15 | 2022-04-28 |
| Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial 15-methyl prostaglandin F2α, Methylergonovine Maleate - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Completed | Brigham and Women's Hospital | 100 | 2019-03-01 | 2025-10-16 |
| Exploration and Determination of Genomic Markers Predictive of Uterine Atony Analysis of genomic markers in uterine atony - Uterine Atony | Completed | Baylor Research Institute | 21 | 2018-02-02 | 2026-01-26 | |
| Role of Tranexamic Acid Versus Uterine Cooling at Caesarean Section Tranexamic Acid, Intraoperative Uterine Cooling - Hemorrhage of Cesarean Section and/or Perineal Wound, Postpartum Hemorrhage | Phase 4 | Completed | Talkha Central Hospital | 100 | 2016-06-01 | 2016-09-05 |
| An Evidence Based Protocol for Oxytocin Administration in Vaginal Delivery Oxytocin - Uterine Atony, Postpartum Hemorrhage | Phase 4 | Withdrawn | NYU Langone Health | 2015-11-01 | 2017-07-31 | |
| Novel Approach of Hayman Uterine Compression Sutures for Management of Severe Atonic Postpartum Hemorrhage: Three Vertical Sutures Patients with three vertical Hayman Sutures - Uterine Atony | Completed | Pınar Yalcin bahat | 50 | 2015-08-15 | 2020-12-30 | |
| Cooling the Uterus in C-section After Dysfunctional Labor Cold laparotomy sponges, Pitocin - Blood Loss, Dysfunctional Labor | Not applicable | Terminated | Baylor Research Institute | 8 | 2015-05-14 | 2026-01-26 |
| Uterine Cooling During Cesarean Delivery to Reduce Blood Loss and Incidence of Postpartum Hemorrhage Uterine Cooling - Postpartum Hemorrhage, Uterine Atony | Not applicable | Completed | Baylor Research Institute | 200 | 2013-07-01 | 2018-01-19 |
| Comparison of Two Doses of Carbetocin for Prevention of Uterine Atony, During Elective Cesarean Section Carbetocin - Uterine Atony, Post-partum Hemorrhage | Phase 4 | Completed | Laval University | 72 | 2012-04-01 | 2013-05-29 |
| ED90 Determination of Carbetocin for the Prevention of Uterine Atony in Women Undergoing an Elective Cesarean Delivery Carbetocin - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Unknown | Maisonneuve-Rosemont Hospital | 40 | 2012-03-01 | 2013-02-15 |
| Does Intramyometrial Oxytocin Improve Outcome in Elective Cesarean Delivery? Oxytocin, Saline - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Withdrawn | University of Saskatchewan | 2011-08-01 | 2012-01-11 | |
| Oxytocin And Uterotonic Agent Use For Cesarean Delivery Oxytocin Infusion, Oxytocin Bolus - Uterine Atony, Hypotension | Phase 4 | Completed | Brigham and Women's Hospital | 60 | 2011-04-01 | 2017-06-29 |
Showing 20 of 22. Sign in to see all of them.
Uterine Inertia (22) · Postpartum Hemorrhage (15) · Hemorrhage (4) · Blood Loss, Surgical (2) · Dystocia (1) · Hypotension (1) · Postoperative Hemorrhage (1)
Female Urogenital Diseases and Pregnancy Complications (22) · Obstetric Labor Complications (22) · Pregnancy Complications (22) · Urogenital Diseases (22) · Dystocia (21) · Pathologic Processes (18) · Pathological Conditions, Signs and Symptoms (18) · Puerperal Disorders (15) · Uterine Hemorrhage (15) · Hemorrhage (14) · Intraoperative Complications (2) · Cardiovascular Diseases (1) · Postoperative Complications (1) · Vascular Diseases (1)
Oxytocin (5) · Methylergonovine (3) · Sodium Chloride (3) · carbetocin (3) · Calcium Chloride (2) · Calcium (1) · Calcium Gluconate (1) · Carboprost (1) · Misoprostol (1) · Tranexamic Acid (1) · Uterine Balloon Tamponade (1) · carboprost tromethamine (1)
Baylor Research Institute (3) · Stanford University (3) · Brigham and Women's Hospital (2) · Busra Lekesiz (1) · IWK Health Centre (1) · Johns Hopkins University (1) · Khyber Teaching Hospital (1) · Laval University (1) · Maisonneuve-Rosemont Hospital (1) · Mansoura University (1) · NYU Langone Health (1) · Pınar Yalcin bahat (1) · Stony Brook University (1) · Talkha Central Hospital (1) · University of Alabama at Birmingham (1)
United States (9) · Canada (4) · Turkey (Türkiye) (2) · Egypt (1) · Saudi Arabia (1)
Jack Stecher, MD (2) · Alan T Tita, MD, PhD (1) · Amro M Hetta, M.B., Ch.B. (1) · AnneMarie Opipari, MD (1) · Brendan Carvalho, MBBCh FRCA (1) · Busra Lekesiz (1) · Christian Loubert, MD, FRCPC (1) · David C Campbell, MD, FRCPC (1) · Jade King, BS (1) · Janice L Mitchell, MD (1) · Jess Ansari, MD, MS (1) · Jessica Ansari, MD (1) · Karen Lindeman, MD (1) · Kevin Fitzpatrick, MD (1)
PMID 20238255, PMID 22227638, PMID 33232518, PMID 35447502, PMID 37917943, PMID 39326051
K12HD001258 (1)