Type 2 Diabetes Mellitus: Clinical Trials

1,872 trials for Type 2 Diabetes Mellitus, newest first

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1431 completed, 212 unknown, 99 terminated, 37 recruiting. 505 Not applicable, 365 Phase 3, 280 Phase 1, 278 Phase 4, 249 Phase 2.

By phase and status

PhaseTrialsStatus
Not applicable505Completed 360, Unknown 82, Not yet recruiting 15, Terminated 15, Active not recruiting 11, Recruiting 9, Withdrawn 8, Suspended 3, Enrolling by invitation 2
Phase 3365Completed 297, Terminated 28, Unknown 21, Recruiting 10, Withdrawn 4, Not yet recruiting 3, Active not recruiting 2
Phase 1280Completed 243, Unknown 18, Terminated 10, Withdrawn 4, Active not recruiting 3, Recruiting 1, Suspended 1
Phase 4278Completed 219, Unknown 31, Terminated 19, Withdrawn 3, Not yet recruiting 2, Recruiting 2, Enrolling by invitation 1, Suspended 1
Phase 2249Completed 196, Terminated 19, Unknown 19, Withdrawn 7, Active not recruiting 5, Not yet recruiting 2, Recruiting 1
Early Phase 115Completed 12, Unknown 2, Active not recruiting 1

Follow Type 2 Diabetes Mellitus: new trials by email Literature Review of Type 2 Diabetes Mellitus trials Research Report on Type 2 Diabetes Mellitus

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Testing a Diabetes Care Program in Rural and Low-Income Clinics
Community Health Worker-led diabetes program - Type 2 Diabetes Mellitus
Not applicableNot yet recruitingThe University of Texas Medical Branch, Galveston2002027-03-012026-08-14
Diabetes Distress, Medication Adherence Barriers, Self-Management, and Glycemic Control in Adults With Type 2 Diabetes
Diabetes Distress, Medication Adherence Barriers, Diabetes self-managemen - Type 2 Diabetes Mellitus
Not yet recruitingBilecik Seyh Edebali Universitesi1372026-12-152026-10-06
A Clinical Study to Evaluate the Effects of Enicepatide Versus Tirzepatide in Participants With Type 2 Diabetes and Inadequate Blood Sugar Control on Oral Glucose-Lowering Medications
Enicepatide, Tirzepatide - Type 2 Diabetes Mellitus
Phase 3Not yet recruitingHoffmann-La Roche9482026-12-012026-10-22
Preventive Effectiveness of Primary Care Physician-led CGM-supported Comprehensive Intervention on Cardio-metabolic-immune Diseases in Community Patients With Type 2 Diabetes (Community Diabetes Control Project)
comprehensive intervention - Type 2 Diabetes Mellitus
Not applicableNot yet recruitingXiangya Hospital of Central South University154002026-11-302026-10-21
Sleep Quality, Adiposity and Diet Quality
Type 2 Diabetes Mellitus, Health Adult Subjects
Not yet recruitingIzmir Democracy University2092026-11-152026-10-13
Clinical Predictors and Therapeutic Gaps in CKM Syndrome Among Adults With Type 2 Diabetes
clinical and laboratory CKM staging evaluation - Type 2 Diabetes Mellitus, Cardiovascular-Kidney-Metabolic Syndrome
Not yet recruitingAssiut University2312026-10-202026-10-02
Clinical Decision Support for SGLT2i After AKI in Type 2 Diabetes
Clinical Decision Support Message - Type 2 Diabetes Mellitus, Acute Kidney Injury
Not applicableNot yet recruitingUniversity of Minnesota2502026-10-202026-10-09
Soluble TREM-1 in Diabetes-Associated Cardiovascular Complications
Type 2 Diabetes Mellitus, Cardiovascular Diseases
Not yet recruitingAssiut University852026-10-012026-09-29
Platelet Indices and Blood Groups in Type 2 Diabetes Vascular Complications
Type 2 Diabetes Mellitus, Vascular Complications
Not yet recruitingAssiut University1002026-09-262026-09-29
A Single-Dose Pharmacokinetic Study of HRS-4729 Injection in Healthy Participants and Patients With Renal Impairment
HRS-4729 - Overweight/Obesity, Metabolic Dysfunction-associated Steatotic Liver Disease/Steatohepatitis (MASLD/MASH)
Phase 1RecruitingFujian Shengdi Pharmaceutical Co., Ltd.322026-09-092026-09-16
Efficacy and Safety of Hebenrun in Patients With Type 2 Diabetes
Metformin, Hebenrun - Type 2 Diabetes Mellitus
Not applicableNot yet recruitingJiangxi University of Traditional Chinese Medicine1102026-09-012026-08-17
Glycemic Velocity and Early Retinal Microvascular Change With GLP-1RA Versus SGLT2i Initiation in Type 2 Diabetes (GLIDE)
GLP-1 Receptor Agonists, SGLT2 inhibitor - Type 2 Diabetes Mellitus, Diabetic Retinopathy (DR)
Not yet recruitingThammasat University Hospital1262026-09-012026-08-31
Integrated Diabetes and Oral Health Care in Oman
Health Belief Model-Based Integrated Diabetes-Oral Health Educational Intervention, Standard Diabetes Education and Routine Care - Type 2 Diabetes Mellitus, Periodontitis
Not applicableNot yet recruitingOman Ministry of Health2902026-09-012026-09-09
Systemic Immune-Inflammation Index and Platelet Parameters in Diabetic Kidney Disease
Diabetic Kidney Disease, Diabetic Nephropathies
Not yet recruitingAssiut University1202026-09-012026-08-19
Incretin Therapy and Exercise in Type 2 Diabetes
Structured Exercise Program - Type 2 Diabetes Mellitus
Not applicableNot yet recruitingUniversity of Regina1102026-09-012026-09-22
Continued Access to the Endogenex System for Participants in the ReCET Pivotal Study
Endogenex System - Type 2 Diabetes Mellitus, Type2diabetes
Not applicableEnrolling by invitationEndogenex, Inc.502026-09-012026-10-19
A Study to Evaluate the Efficacy and Safety of DA-302168S Tablets in Subjects With Type 2 Diabetes
DA-302168S, Placebo of DA-302168S - Type 2 Diabetes Mellitus
Phase 2Not yet recruitingChendu DIAO Pharmaceutical Group CO., LTD.2722026-08-302026-08-31
"Ultrasound-Enhanced Propolis Therapy for Healing Diabetic Foot Wounds"
Sham ultrasound (placebo), Propolis gel (10%) - Diabetic Foot Ulcer t, Type 1 Diabetes Mellitus
Not applicableNot yet recruitingSinai University802026-08-302026-08-04
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
ASC30 tablets A1, Placebo - Obesity, Overweight
Phase 3RecruitingAscletis Pharma (China) Co., Limited15602026-08-282026-09-16
Huangqi Gegen Decoction for Endothelial Function in Type 2 Diabetes at Very High ASCVD Risk
Huangqi Gegen Decoction Granules, Placebo Granules, Conventional Treatment - Type 2 Diabetes Mellitus, Endothelial Dysfunction
Not applicableActive not recruitingPutuo Hospital, Shanghai University of Traditional Chinese Medicine902026-08-042026-08-20

Showing 20 of 1872. Sign in to see all of them.

Narrower conditions

Diabetes Mellitus, Type 2 (1872)  ·  Diabetes Mellitus (287)  ·  Obesity (133)  ·  Insulin Resistance (113)  ·  Hypertension (45)  ·  Diabetes Mellitus, Type 1 (43)  ·  Cardiovascular Diseases (41)  ·  Renal Insufficiency, Chronic (39)  ·  Motor Activity (37)  ·  Overweight (33)  ·  Glucose Intolerance (30)  ·  Hyperglycemia (23)  ·  Diabetic Nephropathies (22)  ·  Dyslipidemias (19)  ·  Inflammation (19)

Broader conditions

Nutritional and Metabolic Diseases (1869)  ·  Endocrine System Diseases (1859)  ·  Glucose Metabolism Disorders (1859)  ·  Metabolic Diseases (1857)  ·  Diabetes Mellitus (1585)  ·  Pathological Conditions, Signs and Symptoms (256)  ·  Signs and Symptoms (178)  ·  Nutrition Disorders (151)  ·  Body Weight (148)  ·  Overnutrition (146)  ·  Hyperinsulinism (125)  ·  Overweight (113)  ·  Cardiovascular Diseases (107)  ·  Vascular Diseases (99)  ·  Urogenital Diseases (95)

Interventions

Metformin (219)  ·  Sitagliptin Phosphate (119)  ·  Insulin Glargine (100)  ·  glimepiride (62)  ·  Pioglitazone (58)  ·  Insulin (57)  ·  dapagliflozin (57)  ·  Exenatide (54)  ·  Exercise (37)  ·  saxagliptin (36)  ·  Liraglutide (33)  ·  Vildagliptin (30)  ·  lixisenatide (26)  ·  (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol (25)  ·  ipragliflozin (25)

Sponsors

AstraZeneca (126)  ·  Merck Sharp & Dohme LLC (108)  ·  Sanofi (80)  ·  Eli Lilly and Company (37)  ·  Takeda (34)  ·  Astellas Pharma Inc (21)  ·  Tanabe Pharma Corporation (21)  ·  Bayer (18)  ·  GlaxoSmithKline (18)  ·  Lexicon Pharmaceuticals (17)  ·  Pfizer (15)  ·  Novartis Pharmaceuticals (14)  ·  Chong Kun Dang Pharmaceutical (13)  ·  Maastricht University Medical Center (13)  ·  Daiichi Sankyo (11)

Countries

United States (561)  ·  China (204)  ·  South Korea (147)  ·  Germany (136)  ·  Canada (130)  ·  Japan (130)  ·  United Kingdom (88)  ·  Mexico (83)  ·  India (76)  ·  Poland (73)  ·  Spain (72)  ·  Italy (71)  ·  Hungary (69)  ·  Denmark (67)  ·  Taiwan (65)

Top investigators

Kazuoki Kondo, MD (14)  ·  James Malone, MD (13)  ·  Lisa Porter, MD (9)  ·  Suman Wason, MD (9)

Results publications

PMID 38770818, PMID 22236356, PMID 31606880, PMID 31797522, PMID 32324065, PMID 32324082, PMID 32372382, PMID 32648108, PMID 34213819, PMID 23748506, PMID 32306296, PMID 32501595, PMID 33166419, PMID 39963952, PMID 22913891, PMID 26894924, PMID 32700393, PMID 33813736, PMID 35210595, PMID 23522121, PMID 30160030, PMID 30366067, PMID 30957581, PMID 31064361, PMID 37526908, PMID 37668888, PMID 39171639, PMID 39531161, PMID 15367925, PMID 17375138, PMID 20092585, PMID 20470226, PMID 20668152, PMID 20807873, PMID 21235696, PMID 22106975, PMID 22405352, PMID 22739142, PMID 23039868, PMID 23536583, PMID 23549864, PMID 23748507, PMID 23986513, PMID 24205974, PMID 24843617, PMID 25537783, PMID 25861982, PMID 28606095, PMID 28774271, PMID 29370218

NIH funding

2017 (14), 2016 (11), 2014 (9), 2025 (7), 2009 (6), 2015 (6), 2019 (5), 2008 (3), 2023 (3), U54RR014616 (3), 2018 (2), K23DK075907 (2), P20GM109096 (2), R01DK082396 (2), R01DK088126 (2)