52 completed, 2 terminated, 1 recruiting. 22 Phase 1, 19 Phase 3, 5 Phase 2, 5 Phase 4.
By phase and status
Follow ipragliflozin: new trials by email Literature Review of ipragliflozin trials Research Report on ipragliflozin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
SGLT2 Inhibitors on Clinical Outcomes and Left Ventricular Remodeling in Type 2 Diabetic Patients with Acute Myocardial Infarction, a Prospective, Multi-center Registry Study SGLT2 inhibitor - Myocardial Infarction, Diabetes Mellitus, Type 2 | | Recruiting | 1000 | 2020-08-01 | 2025-01-03 |
Efficacy of Ipragliflozin Compared With Sitagliptin in Uncontrolled Type 2 Diabetes With Sulfonylurea and Metformin Ipragliflozin, Sitagliptin - Type 2 Diabetes Mellitus | Phase 3 | Completed | 170 | 2017-04-25 | 2022-10-04 |
A Study to Evaluate the Renal Protective Effect (Urine Albumin-to-Creatinine Ratio (UACR)), Efficacy and Safety of Ipragliflozin in Type 2 Diabetes Mellitus Patients With Albuminuria metformin, ipragliflozin, glimepiride - Type 2 Diabetes Mellitus | Phase 4 | Terminated | 33 | 2017-04-25 | 2024-11-08 |
A Study of ASP1941 in Combination With Insulin in Patients With Type 1 Diabetes Mellitus ipragliflozin, Placebo, Insulin Therapy - Type 1 Diabetes Mellitus | Phase 3 | Completed | 175 | 2016-08-29 | 2024-11-12 |
Study of Ipragliflozin in Patients With Type 2 Diabetes Mellitus Receiving Insulin Therapy Ipragliflozin, Insulin - Type 2 Diabetes Mellitus | Phase 4 | Completed | 103 | 2016-07-29 | 2024-11-12 |
A Study to Assess the Efficacy and Safety of Ipragliflozin in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin Ipragliflozin L-proline, Metformin, Placebo - Type 2 Diabetes Mellitus | Phase 3 | Completed | 268 | 2016-05-11 | 2024-11-12 |
Effects of Ipragliflozin on Excessive Fat in Type 2 Diabetes Patients With Non-alcoholic Fatty Liver Disease Treated With Metformin and Pioglitazone Ipragliflozin, metformin with pioglitazone - Type 2 Diabetes With Non-alcoholic Fatty Liver (NAFLD) | Phase 4 | Completed | 44 | 2016-04-26 | 2017-06-23 |
Double-blind Ipragliflozin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Sitagliptin (MK-0431J-843) Ipragliflozin, Placebo, Sitagliptin - Type 2 Diabetes Mellitus | Phase 3 | Completed | 143 | 2015-11-09 | 2018-09-04 |
Double-blind Sitagliptin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Ipragliflozin (MK-0431J-842) Sitagliptin, Placebo, Ipragliflozin - Type 2 Diabetes Mellitus | Phase 3 | Completed | 141 | 2015-11-05 | 2018-08-31 |
Ipragliflozin Add-on Long-term Study in Japanese Participants With Type 2 Diabetes Mellitus on Sitagliptin (MK-0431J-849) Ipragliflozin, Sitagliptin - Type 2 Diabetes Mellitus | Phase 3 | Completed | 77 | 2015-10-26 | 2018-09-04 |
Pharmacodynamics, Pharmacokinetics, and Safety of ASP1941 in Patients With Type 1 Diabetes Mellitus Placebo, ASP1941 - Type 1 Diabetes Mellitus | Phase 2 | Completed | 43 | 2015-09-01 | 2024-11-12 |
A Study to Assess the Efficacy and Safety of ASP1941 in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin ASP1941, Placebo - Type 2 Diabetes Mellitus | Phase 3 | Completed | 143 | 2015-06-22 | 2024-11-12 |
Investigation for Clinical Efficacy and Safety of Ipragliflozin 50mg and 100mg on Type II Diabetes Ipragliflozin (SGLT2 inhibitor) - Diabetes Mellitus, Type 2 | | Completed | 231 | 2014-11-01 | 2018-04-17 |
Post-Marketing Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Ipragliflozin in Combination With GLP-1 Receptor Agonists in Japanese Patients With Type 2 Diabetes Mellitus (T2DM) Ipragliflozin - Type 2 Diabetes Mellitus | Phase 4 | Completed | 100 | 2014-10-08 | 2024-11-08 |
Specified Drug Use Results Survey of Ipragliflozin Treatment in type2 Diabetes Patients ipragliflozin - Type 2 Diabetes | | Completed | 11412 | 2014-07-17 | 2024-10-22 |
The Survey of Ipragliflozin Treatment in Elderly type2 Diabetes Patients SuglatĀ® - Type 2 Diabetes | | Completed | 8687 | 2014-04-01 | 2015-10-15 |
A Study to Assess the Efficacy and Safety of Ipragliflozin in Combination With Insulin in Subjects With Type 2 Diabetes Mellitus ipragliflozin, placebo - Type 2 Diabetes Mellitus | Phase 4 | Completed | 262 | 2014-03-31 | 2024-11-08 |
A Study to Compare the Oral Absorption of ASP1941 Among Two Types of Tablets ASP1941 - Healthy, Plasma Concentration of ASP1941 | Phase 1 | Completed | 32 | 2013-09-01 | 2014-02-07 |
A Study to Evaluate Long-term Safety and Efficacy of ASP1941 in Diabetes Patients ipragliflozin - Type 2 Diabetes Mellitus | Phase 3 | Completed | 174 | 2012-05-25 | 2024-11-08 |
A Study to Assess the Efficacy and Safety of ASP1941 in Asian Subjects With Type 2 Diabetes Mellitus ASP1941, acarbose, Placebo - Type II Diabetes Mellitus | Phase 3 | Terminated | 46 | 2012-04-23 | 2024-11-12 |
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Conditions studied
Diabetes Mellitus, Type 2 (35) · Diabetes Mellitus (18) · Glycosuria (3) · Diabetes Mellitus, Type 1 (2) · Renal Insufficiency (2) · Insulin Resistance (1) · Liver Diseases (1) · Myocardial Infarction (1) · Non-alcoholic Fatty Liver Disease (1)
Sponsors
Astellas Pharma Inc (41) · Astellas Pharma Europe B.V. (4) · Merck Sharp & Dohme LLC (3) · Astellas Pharma Korea, Inc. (2) · Astellas Pharma Global Development, Inc. (1) · Kiyuk Chang (1) · Seoul National University Bundang Hospital (1) · Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan (1) · Yonsei University (1)
Countries
Japan (26) · United States (8) · South Korea (7) · Netherlands (4) · United Kingdom (4) · Hungary (3) · Poland (3) · Taiwan (3) · Slovakia (2) · Colombia (1) · Czechia (1) · Germany (1) · India (1) · Italy (1) · Mexico (1)
Top investigators
Haruo Nishimura (1) · Kiyuk Chang, MD, PhD (1) · Soo Lim (1)
Results publications
PMID 31606880, PMID 32839028, PMID 34033212, PMID 21877761, PMID 22795925, PMID 23276620, PMID 23359360, PMID 23910665, PMID 25411597, PMID 26800061, PMID 27463414, PMID 29926400, PMID 30767112, PMID 30800562, PMID 31347926, PMID 31552641, PMID 33565686, PMID 33730336, PMID 34567926, PMID 38770818
NIH funding
2009 (3), 2008 (1)