11 completed, 11 unknown, 6 recruiting, 2 active not recruiting. 7 Not applicable, 6 Phase 1, 6 Phase 2, 4 Phase 3.
Follow Tuberculosis Infection: new trials by email Literature Review of Tuberculosis Infection trials Research Report on Tuberculosis Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacokinetics of Antituberculosis Drugs in Breastfeeding Women Standard dose rifampicin, High dose rifampicin, Standard dose isoniazid - Tuberculosis Infection, Healthy Volunteer | Phase 1 | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 60 | 2026-06-01 | 2026-11-02 |
| Isoniazid-Related Hepatotoxicity in Clinical Practice: Incidence and Predictors Standard isoniazid-based TB/LTBI therapy - Tuberculosis Infection, Tuberculosis Infection, Latent | Not yet recruiting | ASST Fatebenefratelli Sacco | 220 | 2026-05-30 | 2026-03-16 | |
| Window Prophylaxis for Pediatric Tuberculosis Prevention Trial Tuberculosis window prophylaxis with weekly rifapentine and isoniazid for 12 weeks, Standard of care tuberculosis prophylaxis with weekly rifapentine and isoniazid for 12 weeks - Tuberculosis Infection, Household Contacts | Not applicable | Recruiting | Pontificia Universidad Catolica de Chile | 647 | 2025-10-27 | 2025-12-29 |
| 1HP Versus 3HR in the Treatment of Tuberculosis Infection in Vietnam Isoniazid, Rifapentine, Rifampicin - Tuberculosis Infection | Phase 3 | Withdrawn | Freundeskreis Für Internationale Tuberkulosehilfe e.V | 2024-11-01 | 2026-09-09 | |
| Effects of Tuberculosis Infection on Development and Function of the Placenta TB infection - Pregnancy Related, Tuberculosis Infection | Recruiting | Lund University | 500 | 2024-10-01 | 2026-09-03 | |
| BCG Revaccination in Children and Adolescents BCG vaccine, Oral Chemoprophylaxis - Tuberculosis Infection, Tuberculosis | Phase 3 | Suspended | Tuberculosis Research Centre, India | 9200 | 2024-07-15 | 2023-12-18 |
| Analysis of Liver Injury Risk Factors in a Multiethnic Population Treated With Antituberculosis Drugs standard anti-TB treatment - Tuberculosis Infection | Unknown | Stefania Cheli | 127 | 2024-07-05 | 2024-08-06 | |
| Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV Rifapentine, Isoniazid - HIV Seropositivity, Pregnancy | Phase 1 / Phase 2 | Active not recruiting | The Aurum Institute NPC | 252 | 2024-01-17 | 2025-12-12 |
| Testing Health Workers At Risk to Advance Our Understanding of TB Infection TB infection testing - Tuberculosis, Tuberculosis Infection | Recruiting | Beth Israel Deaconess Medical Center | 300 | 2024-01-15 | 2026-07-08 | |
| Short-course Regimens for the Treatment of Pulmonary Tuberculosis Rifabutin, Delamanid, Bedaquiline - Tuberculosis, Pulmonary, Tuberculosis Infection | Phase 2 / Phase 3 | Active not recruiting | Centers for Disease Control and Prevention | 288 | 2023-11-21 | 2026-09-21 |
| Closing -TB GAPs - for People Living With HIV: TB Guidance for Adaptable Patient-Centered Service patient-centered TB preventive therapy, TB preventive therapy adherence support - Tuberculosis, HIV Coinfection | Not applicable | Completed | Baylor College of Medicine | 5733 | 2023-07-11 | 2026-11-04 |
| Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin rifampicin - Pediatric HIV Infection, Tuberculosis Infection | Phase 1 | Recruiting | Brigham and Women's Hospital | 20 | 2023-07-07 | 2026-07-30 |
| Evaluation of ТВ/Flu-05Е Vaccine for the Prevention of Tuberculosis Infection in BCG-vaccinated Volunteers Aged 18-50 Years TB/Flu-05E vaccine, Placebo - Tuberculosis Infection | Phase 1 | Completed | Tatyana Zubkova | 51 | 2023-05-10 | 2024-04-18 |
| Point of Care Tests to Identify Opportunistic Infections in Advanced HIV Patients in Mexico City Histoplasma Urine Antigen Lateral Flow Antigen test, Cryptococcal Lateral Flow Antigen test, Tuberculosis-lipoarabinomannan Lateral Flow Antigen test - Acquired Immunodeficiency Syndrome, Histoplasmosis AIDS | Not applicable | Unknown | National Institute of Respiratory Diseases, Mexico | 211 | 2023-04-01 | 2023-01-17 |
| Point-of-care Pharmacogenomic Testing to Optimize Isoniazid Dosing for Tuberculosis Prevention Low-dose isoniazid, Standard dose of isoniazid, High-dose isoniazid - Tuberculosis Infection, Isoniazid Adverse Reaction | Phase 1 | Completed | Stanford University | 78 | 2023-03-23 | 2026-06-15 |
| Multicenter Italian Cohort Study on Tuberculosis in Pediatric Age Tuberculosis Infection | Recruiting | Meyer Children's Hospital IRCCS | 1000 | 2022-12-22 | 2024-03-04 | |
| Collision of Three Global Pandemics: the Effect of Tuberculosis and HIV on the Epidemiological, Clinical, Virological and Immunological Trajectory of COVID-19 in Botswana and Namibia Covid-19, TB and HIV diagnosis - COVID-19, HIV Seropositivity | Completed | University of Namibia | 1750 | 2022-08-01 | 2024-10-24 | |
| Effect of Integrating Traditional Tuberculosis Care With Modern Health Care on Case Detection Training for traditional and modern care providers - Tuberculosis, Tuberculosis, Pulmonary | Not applicable | Completed | Bahir Dar University | 918 | 2022-07-01 | 2024-07-09 |
| Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy Nivaquine ® (Chloroquine) - Tuberculosis Infection | Phase 1 | Unknown | University of Zurich | 16 | 2022-01-04 | 2024-07-01 |
| Immunization With BCG Vaccine to Prevent Tuberculosis Infection BCG (Tokyo 172) vaccine, Placebo - Tuberculosis Infection | Phase 3 | Terminated | Henry M. Jackson Foundation for the Advancement of Military Medicine | 16 | 2021-12-01 | 2026-01-23 |
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Latent Tuberculosis (36) · Tuberculosis (14) · Tuberculosis, Pulmonary (5) · HIV Infections (4) · COVID-19 (2) · Chemical and Drug Induced Liver Injury (2) · Communicable Diseases (2) · HIV Seropositivity (2) · Tuberculosis, Multidrug-Resistant (2) · Acquired Immunodeficiency Syndrome (1) · Breast Feeding (1) · Cross Infection (1) · Drug-Related Side Effects and Adverse Reactions (1) · Hepatitis C (1) · Meningitis, Cryptococcal (1)
Actinomycetales Infections (36) · Bacterial Infections (36) · Bacterial Infections and Mycoses (36) · Gram-Positive Bacterial Infections (36) · Infections (36) · Latent Infection (36) · Mycobacterium Infections (36) · Tuberculosis (22) · Urogenital Diseases (8) · Blood-Borne Infections (7) · Genital Diseases (7) · Immune System Diseases (7) · Immunologic Deficiency Syndromes (7) · Lentivirus Infections (7) · Lung Diseases (7)
Isoniazid (7) · Rifampin (5) · rifapentine (3) · Chemoprevention (2) · Ethambutol (2) · Pyrazinamide (2) · bedaquiline (2) · Art Therapy (1) · Aspirin (1) · BCG Vaccine (1) · Blood Specimen Collection (1) · Chloroquine (1) · Control Groups (1) · Ibuprofen (1) · Levofloxacin (1)
JHP Pharmaceuticals LLC (2) · Oxford University Clinical Research Unit, Vietnam (2) · ANRS, Emerging Infectious Diseases (1) · ASST Fatebenefratelli Sacco (1) · Aeras (1) · Asan Medical Center (1) · Bahir Dar University (1) · Baylor College of Medicine (1) · Beth Israel Deaconess Medical Center (1) · Brigham and Women's Hospital (1) · Centers for Disease Control and Prevention (1) · Eleonora Nucera (1) · Freundeskreis Für Internationale Tuberkulosehilfe e.V (1) · Fundació Institut Germans Trias i Pujol (1) · Henry M. Jackson Foundation for the Advancement of Military Medicine (1)
South Africa (6) · Italy (4) · United States (4) · Vietnam (4) · Ethiopia (3) · China (2) · Malawi (2) · Tanzania (2) · Uganda (2) · Brazil (1) · Cambodia (1) · Canada (1) · Chile (1) · Eswatini (1) · France (1)
Heiman F Wertheim, PhD (2) · Aishwarya Venkataraman, MRCPCH (1) · Angela Rizzi, MD, PhD (1) · Antonio Gasbarrini, Prof., MD (1) · Cristina Vilaplana, MD, PhD (1) · Daniel W Fitzgerald, MD (1) · Dereck Tait, MD (1) · Dick Menzies, MD (1) · Domenico Staiti, Prof., MD (1) · Dr Vaneshree Govender (1) · Ekaterina V Kurbatova, MD, PhD, MPH (1) · Eleonora G Nucera, Prof., MD (1) · Holly Rawizza, MD, MPH (1) · Jason R Andrews, MD (1)
PMID 22161161, PMID 22923457, PMID 27223167, PMID 27862893, PMID 29978556, PMID 31862768, PMID 32412638, PMID 32899054, PMID 33584652, PMID 34319803, PMID 35035549, PMID 35177220, PMID 35969076, PMID 36186786, PMID 36558815, PMID 37572363, PMID 37697429, PMID 37813532, PMID 38748183, PMID 39252005, PMID 39533424, PMID 39727196, PMID 39871048, PMID 40025607, PMID 40132007, PMID 40915316
R21AI172182 (1)