10 recruiting, 4 not yet recruiting, 2 active not recruiting, 2 completed. 9 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Recruiting 5, Active not recruiting 2, Completed 2 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Tricuspid Regurgitation (TR): new trials by email Literature Review of Tricuspid Regurgitation (TR) trials Research Report on Tricuspid Regurgitation (TR)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Categorizing Patient Risk for Tricuspid Regurgitation (TR) Intervention With Admittance Pulmonary Artery Catheter System (APACS) Right Heart Catheterization - Tricuspid Regurgitation (TR) | Not yet recruiting | Feldman Cardiology, PLLC | 8 | 2027-07-10 | 2026-03-30 | |
| PASCAL Precision-GDMT Registry Tricuspid Insufficiency, Tricuspid Regurgitation (TR) | Not yet recruiting | Ceric Sàrl | 50 | 2026-08-01 | 2026-05-13 | |
| Pivotal Trial to Evaluate TraNsvenous TrIcuspid Valve ReplacemenT With LuX-Valve Plus System (The TRINITY Pivotal Trial) TTVI with LuX-Valve Plus System, TTVI with EVOQUE - Tricuspid Regurgitation (TR) | Not applicable | Recruiting | Jenscare Innovation Inc. | 680 | 2026-07-15 | 2026-08-28 |
| The TRICURE US IDE Pivotal Study TRiCares Topaz TTVR System, Edwards EVOQUE TTVR System - Tricuspid Regurgitation (TR) | Not applicable | Recruiting | TRiCares | 831 | 2026-07-08 | 2026-10-22 |
| A Post-Market Assessment of the Safety and Performance of the TriClip™ System Tricuspid Transcatheter Edge-to-Edge Repair (TEER) - Tricuspid Regurgitation (TR) | Recruiting | Abbott Medical Devices | 1000 | 2026-07-02 | 2026-10-06 | |
| Efficacy of Verciguat in TR and RV Failure Vericiguat - HFrEF, Tricuspid Regurgitation (TR) | Phase 4 | Not yet recruiting | Daejeon St. Mary's hospital | 100 | 2026-07-01 | 2026-06-25 |
| Natural History of Atrial Fibrillation-Induced Tricuspid Valve Remodeling in the Absence of Significant Tricuspid Regurgitation: A Three-Dimensional Echocardiographic Study Atrial Fibrillation (AF), Tricuspid Regurgitation (TR) | Recruiting | Centro Cardiologico Monzino | 66 | 2026-05-04 | 2026-06-01 | |
| DELINEATE-Prospective Valve Disease, Aortic, Mitral Regurgitation (MR) | Recruiting | Columbia University | 50 | 2026-04-15 | 2026-04-16 | |
| Robotic Transjugular Transcatheter Tricuspid Valve Replacement Transcatheter tricuspid valve replacement - Tricuspid Regurgitation (TR), Valvular Heart Diseases | Not applicable | Recruiting | Prince of Wales Hospital, Shatin, Hong Kong | 10 | 2026-03-12 | 2026-09-18 |
| Efficacy of Early Rhythm Control in AF With TR Patients Anti-arrhythmic drugs for rhythm control, DC cardioversion, catheter ablation for rhythm control, Usual care - Atrial Fibrillation (AF), Tricuspid Regurgitation (TR) | Recruiting | Samsung Medical Center | 5800 | 2026-02-18 | 2026-05-29 | |
| Safety and Feasibility Study: Transcatheter Valve Repair in Severe Symptomatic Functional Tricuspid Regurgitation Tricuspid Annular Therapy System - Tricuspid Regurgitation Functional, Tricuspid Regurgitation (TR) | Not applicable | Recruiting | Tangent Cardiovascular Inc. | 25 | 2025-07-15 | 2026-10-13 |
| Early Feasibility of 'Pivot Extend' for Tricuspid Regurgitation Treatment Pivot Extend Tricuspid Regurgitation Spacer Device - Tricuspid Regurgitation (TR) | Not applicable | Recruiting | Tau-MEDICAL Co., Ltd. | 7 | 2025-05-01 | 2025-04-11 |
| Impact of Severe Tricuspid Regurgitation Correction on Gut Microbiota and Gastrointestinal Function Tricuspid Regurgitation (TR) | Not yet recruiting | Francesco Maisano | 150 | 2025-03-31 | 2025-03-30 | |
| LuX-Valve Plus System for Severe or Greater Tricuspid Regurgitation Transvenous Tricuspid Valve System implantation + OMT, OMT - Tricuspid Regurgitation (TR) | Not applicable | Active not recruiting | Jenscare Scientific | 126 | 2024-10-09 | 2026-07-15 |
| TraNsvenous TrIcuspid Valve ReplacemenT With LuX-Valve Plus System (TRINITY-US) Transcatheter Tricuspid Valve Intervention - Tricuspid Regurgitation (TR) | Not applicable | Active not recruiting | Jenscare Innovation Inc. | 15 | 2024-09-26 | 2026-03-02 |
| Ambulant Monitoring to Detect Hemodynamic and Electrical Impact of Severe Tricuspid Valve Regurgitation 14 days ambulatory rhythm monitoring - Tricuspid Regurgitation (TR) | Not applicable | Completed | Universitaire Ziekenhuizen KU Leuven | 20 | 2024-02-01 | 2025-06-29 |
| Pacemaker Implantation Following Transcatheter Tricuspid Valve Replacement AV Block Complete, Tricuspid Regurgitation (TR) | Recruiting | Deutsches Herzzentrum Muenchen | 25 | 2024-01-01 | 2025-02-07 | |
| Virtual Reality Reduces Pre-Procedural Anxiety in TEER Patients, But Timing Seems Crucial Standard Education plus Virtual Reality (VR) - Anxiety, Mitral Regurgitation | Not applicable | Completed | Abby Geerlings | 75 | 2021-10-01 | 2025-12-04 |
Tricuspid Valve Insufficiency (18) · Heart Valve Diseases (3) · Atrial Fibrillation (2) · Mitral Valve Insufficiency (2) · Anxiety Disorders (1) · Aortic Valve Disease (1) · Aortic Valve Insufficiency (1) · Aortic Valve Stenosis (1) · Cardiovascular Diseases (1) · Ventricular Dysfunction, Left (1)
Heart Diseases (18) · Cardiovascular Diseases (17) · Heart Valve Diseases (15) · Arrhythmias, Cardiac (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Mental Disorders (1) · Ventricular Dysfunction (1) · Ventricular Outflow Obstruction (1)
Catheter Ablation (1) · Drug Delivery Systems (1) · vericiguat (1)
Jenscare Innovation Inc. (2) · Abbott Medical Devices (1) · Abby Geerlings (1) · Centro Cardiologico Monzino (1) · Ceric Sàrl (1) · Columbia University (1) · Daejeon St. Mary's hospital (1) · Deutsches Herzzentrum Muenchen (1) · Feldman Cardiology, PLLC (1) · Francesco Maisano (1) · Jenscare Scientific (1) · Prince of Wales Hospital, Shatin, Hong Kong (1) · Samsung Medical Center (1) · TRiCares (1) · Tangent Cardiovascular Inc. (1)
United States (5) · Italy (3) · Germany (2) · South Korea (2) · Belgium (1) · Canada (1) · China (1) · Georgia (1) · Hong Kong (1) · Netherlands (1) · Paraguay (1) · Spain (1)
Gianluca Pontone, MD (1) · Meghan Griffin (1) · Neil Fam, MD (1) · Pierre A Elias, MD (1) · Pradeep Yadav, MD (1) · Thibault Lhermusier, MD, PhD (1)