21 completed. 21 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 21 | Completed 21 |
| Phase 2 | 4 | Completed 4 |
Follow Thinness: new trials by email Literature Review of Thinness trials Research Report on Thinness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Alternative RUTFs for Treatment of Child Wasting Soy-based RUTF, Soy-maize-sorghum-based RUTF, Standard RUTF - Severe Acute Malnutrition, Moderate Acute Malnutrition | Phase 3 | Completed | International Food Policy Research Institute | 2269 | 2025-03-21 | 2026-05-13 |
| A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) - 2 anamorelin HCl, Placebo Oral Tablet - Cachexia; Cancer, Non Small Cell Lung Cancer | Phase 3 | Completed | Helsinn Healthcare SA | 318 | 2019-05-06 | 2026-10-06 |
| A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) - 1 Anamorelin Hydrochloride, Placebo Oral Tablet - Cachexia; Cancer, Non Small Cell Lung Cancer | Phase 3 | Completed | Helsinn Healthcare SA | 318 | 2019-03-05 | 2026-10-06 |
| Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy standard care, nutritional supplements and advice, home-based self-assisted exercise program - Cachexia, Neoplasms | Phase 3 | Completed | Norwegian University of Science and Technology | 221 | 2015-04-01 | 2025-08-29 |
| Reformulated F75 Milk to Treat Severe Acute Malnutrition Standard F75 Milk, Modified F75 Milk - Malnutrition, Diarrhoea | Phase 2 / Phase 3 | Completed | University of Oxford | 842 | 2014-12-01 | 2016-04-14 |
| Complementary Food Supplements for Reducing Childhood Undernutrition Wheat Soy Blend (WSB++), Chickpea based complementary food supplement, Rice based complementary food supplement - Stunting, Wasting | Phase 2 / Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 5449 | 2012-09-01 | 2018-08-24 |
| Soy-Ready to Use Therapeutic Food (RUTF) in Severely Malnourished Children Soy-based RUTF (in double blind design) - Severe Acute Malnutrition, Severe Wasting | Phase 2 / Phase 3 | Completed | International Centre for Diarrhoeal Disease Research, Bangladesh | 260 | 2012-07-01 | 2017-09-25 |
| Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 2) Anamorelin HCl, Placebo - Cachexia, Non-Small Cell Lung Cancer | Phase 3 | Completed | Helsinn Therapeutics (U.S.), Inc | 495 | 2011-07-01 | 2017-10-27 |
| Anamorelin HCl in the Treatment of Non-Small Cell Lung Cancer-Cachexia (NSCLC-C): An Extension Study (ROMANA 3) Anamorelin HCl, Placebo - Cachexia, Non-Small Cell Lung Cancer | Phase 3 | Completed | Helsinn Therapeutics (U.S.), Inc | 513 | 2011-07-01 | 2017-09-14 |
| Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 1) Anamorelin HCl, Placebo - Cachexia, Non-Small Cell Lung Cancer | Phase 3 | Completed | Helsinn Therapeutics (U.S.), Inc | 484 | 2011-07-01 | 2017-10-27 |
| Olanzapine for the Treatment of Appetite Loss in Amyotrophic Lateral Sclerosis (ALS) Olanzapine - Amyotrophic Lateral Sclerosis (ALS) | Phase 2 / Phase 3 | Completed | Charite University, Berlin, Germany | 40 | 2011-03-01 | 2024-02-14 |
| Cotrimoxazole Prophylaxis in Severely Malnourished Children Cotrimoxazole dispersible tablet, Placebo dispersible tablet - Nutrition Disorders, Life-threatening Infection | Phase 3 | Completed | University of Oxford | 1781 | 2009-11-01 | 2014-08-18 |
| Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer Patients Melatonin, Placebo - Gastrointestinal Cancer, Lung Cancer | Phase 3 | Completed | M.D. Anderson Cancer Center | 82 | 2006-06-01 | 2012-12-11 |
| Creatine in Treating Patients With Cancer-Associated Weight Loss creatine monohydrate, placebo - Anorexia, Cachexia | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 300 | 2004-12-01 | 2020-04-29 |
| Etanercept in Treating Cancer-Related Cachexia and Anorexia in Patients With Advanced Cancer etanercept - Anorexia, Cachexia | Phase 3 | Completed | Mayo Clinic | 2003-05-01 | 2011-05-05 | |
| Comparison of Nutritional Supplements in Preventing Weight Loss in Patients With Cancer Juven, Non-Juven Supplement - Cachexia, Lymphoma | Phase 3 | Completed | Radiation Therapy Oncology Group | 472 | 2002-12-01 | 2016-12-08 |
| Docetaxel With or Without Infliximab in Treating Weight Loss, Loss of Appetite, and Fatigue in Patients With Unresectable Non-Small Cell Lung Cancer (Infliximab Treatment Discontinued Effective 10/05/05) infliximab, docetaxel, placebo - Anorexia, Cachexia | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 67 | 2002-10-01 | 2016-12-07 |
| Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck Cancer megestrol acetate, quality-of-life assessment - Anorexia, Cachexia | Phase 3 | Completed | Wake Forest University Health Sciences | 13 | 2000-10-01 | 2021-09-09 |
| Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer megestrol acetate, radiation therapy - Anorexia, Cachexia | Phase 3 | Completed | Wake Forest University Health Sciences | 25 | 2000-09-01 | 2021-09-09 |
| Comparison of Megestrol and/or Omega-3 Fatty Acid-Enriched Nutritional Supplement in Treating Patients With Cancer-Related Weight Loss and Lack of Appetite eicosapentaenoic acid, megestrol acetate, placebo - Anorexia, Cachexia | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 429 | 2000-03-01 | 2016-07-14 |
Showing 20 of 21. Sign in to see all of them.
Cachexia (21) · Anorexia (9) · Carcinoma, Non-Small-Cell Lung (7) · Lung Neoplasms (3) · Malnutrition (3) · Neoplasms (3) · Severe Acute Malnutrition (3) · Kwashiorkor (2) · Acquired Immunodeficiency Syndrome (1) · Amyotrophic Lateral Sclerosis (1) · Body Weight (1) · Body Weight Changes (1) · Burkitt Lymphoma (1) · Diarrhea (1) · Esthesioneuroblastoma, Olfactory (1)
Pathological Conditions, Signs and Symptoms (21) · Signs and Symptoms (21) · Body Weight (20) · Body Weight Changes (20) · Weight Loss (20) · Neoplasms by Site (10) · Signs and Symptoms, Digestive (10) · Lung Diseases (8) · Neoplasms (8) · Respiratory Tract Diseases (8) · Respiratory Tract Neoplasms (8) · Thoracic Neoplasms (8) · Bronchial Neoplasms (7) · Carcinoma, Bronchogenic (7)
Megestrol Acetate (4) · Counseling (1) · Creatine (1) · Dietary Supplements (1) · Docetaxel (1) · Eicosapentaenoic Acid (1) · Etanercept (1) · Ibuprofen (1) · Infliximab (1) · Melatonin (1) · Olanzapine (1) · Radiotherapy (1) · Standard of Care (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1) · anamorelin (1)
Alliance for Clinical Trials in Oncology (3) · Helsinn Therapeutics (U.S.), Inc (3) · Helsinn Healthcare SA (2) · University of Oxford (2) · Wake Forest University Health Sciences (2) · Bristol-Myers Squibb (1) · Charite University, Berlin, Germany (1) · International Centre for Diarrhoeal Disease Research, Bangladesh (1) · International Food Policy Research Institute (1) · Johns Hopkins Bloomberg School of Public Health (1) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · Norwegian University of Science and Technology (1) · Radiation Therapy Oncology Group (1)
United States (15) · Canada (5) · Russia (5) · Germany (4) · Hungary (4) · Poland (4) · Australia (3) · Belgium (3) · Italy (3) · Serbia (3) · Ukraine (3) · Bangladesh (2) · Belarus (2) · Czechia (2) · France (2)
Aminah Jatoi, MD (4) · Abu Ahmed Shamim, MS (1) · Alain B Labrique, PhD (1) · Britta Schumacher, PhD (1) · Edward G. Shaw, MD (1) · Hasmot Ali, MPH (1) · James A Berkley (1) · James A Berkley, FRCPCH (1) · Kathryn M. Greven, MD (1) · Keith P West, DrPH (1) · Kerry J Schulze, PhD (1) · Laeticia Toe (1) · Lawrence B. Berk, MD, PhD (1) · Marie Fallon, MD PhD (1)
PMID 28472437, PMID 26906526, PMID 39992021, PMID 15197210, PMID 17674351, PMID 18293016, PMID 19665818, PMID 23439759, PMID 25351456, PMID 27265353, PMID 27680994, PMID 28644348, PMID 29178404, PMID 29635501, PMID 30184222, PMID 30266874, PMID 30807589, PMID 31037340, PMID 31775877, PMID 32240304, PMID 32875267, PMID 33154417, PMID 34528401, PMID 34538239, PMID 39662676
2018 (2)