40 completed, 12 unknown, 1 enrolling by invitation, 1 not yet recruiting. 31 Not applicable, 6 Phase 2, 4 Phase 1, 3 Phase 3, 1 Early Phase 1.
Follow Temporomandibular Disorders: new trials by email Literature Review of Temporomandibular Disorders trials Research Report on Temporomandibular Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Temporomandibular Disorders With and Without Chronic Neck Pain Temporomandibular Disorders | Completed | Hacettepe University | 67 | 2026-06-23 | 2026-08-10 | |
| Three Photobiomodulation Wavelengths (635, 940, and 1064 nm) on Chronic Myogenic Temporomandibular Disorder 635 nm red diode laser, 940 nm NIR diode laser (Biolase), 1064 nm Nd:YAG laser (Fotona) - Temporomandibular Disorders | Not applicable | Not yet recruiting | Alexandria University | 45 | 2026-06-01 | 2026-06-04 |
| Comparison of Dry Needling and Two Botulinum Toxins for Bruxism Dry Needling (DN), PrabotulinumtoxinA, Abobotulinumtoxina - Bruxism, Sleep Bruxism, Adult | Not applicable | Completed | Recep Tayyip Erdogan University | 72 | 2026-01-09 | 2026-05-20 |
| The BETY-Biopsychosocial Questionnaire (BETY-BQ) in Individuals With Temporomandibular Dysfunction-Related Headache Temporomandibular Disorders, Headache | Enrolling by invitation | Hasan Kalyoncu University | 150 | 2025-01-30 | 2025-05-15 | |
| Mandibular Splint vs Botox Injection in Lateral Pterygoid on Cervical Muscle Activity in Patients With Temporomandibular Disorders Botox injection, Mandibular stabilization splint, Muscle relaxant - Mandibular Splint, Botox | Not applicable | Unknown | Cairo University | 33 | 2024-08-14 | 2024-08-16 |
| Relationship Between Smartphone Addiction and Temporomandibular Joint Disorders Among Adults in Egypt. A web based survey - Temporomandibular Disorders, Smartphone Addiction | Unknown | Cairo University | 296 | 2024-02-20 | 2024-02-21 | |
| Effectiveness of Brief Mindfulness-Based Interventions for Painful Temporomandibular Disorders Among University Students Sham BMBI, BMBI - Temporomandibular Disorders, Chronic Pain | Not applicable | Completed | University of Malaya | 127 | 2024-01-12 | 2026-09-02 |
| Effectiveness of the Fascial Distortion Model on the Cervical Spine in Individuals With Temporomandibular Disorder Fascial Distortion Model, Rocabado's 6x6 Exercises, Patient Education - Temporomandibular Disorder, Temporomandibular Disorders | Not applicable | Completed | Hacettepe University | 51 | 2023-12-17 | 2025-03-13 |
| How Dentists' Personality Traits Affect Communication and Treatment Outcomes in TMD Patients Splint Therapy with Structured Communication - Temporomandibular Disorders, Psychological Distress | Completed | Soaad Tolba Mohammed Tolba Badawi | 30 | 2023-12-01 | 2025-07-20 | |
| Peripheral TMD Pain Mechanisms and the Effect by Botulinum Toxin A Botulinum toxin type A, Isotonic saline 0,9% - Temporomandibular Disorders | Phase 2 | Recruiting | Karolinska Institutet | 100 | 2023-11-14 | 2026-08-05 |
| Efficacy of Manuel Therapy and BETY in Patients With Temporomandibular Dysfunction Related Headache Patient education and preventive exercise, Patient education, preventive exercise combined with Manual Therapy protocol, Patient education, preventive exercise combined with BETY approach - Temporomandibular Disorders, Headache | Not applicable | Completed | Hasan Kalyoncu University | 60 | 2023-09-01 | 2025-09-03 |
| Erenumab-aooe for Temporomandibular Disorders Management: TMD Cgrp Antibody RElief (TMD CARE) Erenumab-Aooe 70 MG in 1 mL Prefilled Syringe, Placebo - Temporomandibular Disorders | Phase 2 | Terminated | University of Maryland, Baltimore | 5 | 2022-05-26 | 2024-04-02 |
| Efficacy of the Myofunctional Therapy on Oral Dysphagia Home Exercise, Manual Therapy Combined with Home Exercise, Orofacial Myofunctional Therapy combined with Manual Therapy and Home Exercise - Dysphagia, Oral Phase, Temporomandibular Disorders | Not applicable | Completed | Hasan Kalyoncu University | 60 | 2020-12-01 | 2021-08-25 |
| Temporomandibular Dysfunction Affects Neck Disability, Headache, Anxiety, And Sleep Quality In Women: A Cross-Sectional Study Temporomandibular Disorders, Headache | Completed | Ankara Yildirim Beyazıt University | 212 | 2020-11-25 | 2021-07-01 | |
| Dry Needling vs Injection in Patients With Temporomandibular Disorders Dry needling and placebo injection, Injection and placebo dry needling, Dry needling and injection - Temporomandibular Disorders | Not applicable | Unknown | Josue Fernandez Carnero | 64 | 2020-11-23 | 2023-11-15 |
| Expiratory Muscle Training in Stroke Expiratory muscle training - Stroke, Mastication Disorder | Not applicable | Completed | Abant Izzet Baysal University | 146 | 2020-08-18 | 2023-03-31 |
| Side Effects of Mandibular Advancement Devices H-MAD with a hinge system according to Herbst - Obstructive Sleep Apnea Syndrome, Temporomandibular Disorders | Not applicable | Completed | University Medicine Greifswald | 65 | 2019-12-01 | 2023-06-15 |
| Effects of Electric Massage on the Cervical Region in Subjects Diagnosed With Temporomandibular Disorders Group 1: Manual Therapy, Group 2: Interferential massage plus Manual Therapy - Temporomandibular Disorders | Not applicable | Completed | Luis Espejo Antúnez PhD | 46 | 2019-11-18 | 2021-11-09 |
| Biomarkers Associated With Temporomandibular Disorders in Patients With Rheumatoid Arthritis Temporomandibular Disorders, Rheumatoid Arthritis | Unknown | Josip Juraj Strossmayer University of Osijek | 92 | 2019-11-01 | 2024-07-05 | |
| What Are the Clinical Factors Associated With a Significant Pain Reduction Following Physiotherapy in Patients With Temporomandibular Disorders? Physiotherapy - Manual Therapy - Temporomandibular Disorders | Completed | Istituto Stomatologico Italiano | 180 | 2019-06-14 | 2025-05-14 |
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Temporomandibular Joint Disorders (56) · Pain (8) · Chronic Pain (5) · Headache (4) · Craniomandibular Disorders (3) · Facial Pain (3) · Musculoskeletal Diseases (3) · Temporomandibular Joint Dysfunction Syndrome (3) · Deglutition Disorders (2) · Myalgia (2) · Stomatognathic Diseases (2) · Agnosia (1) · Anxiety Disorders (1) · Arthritis, Rheumatoid (1) · Bruxism (1)
Jaw Diseases (56) · Joint Diseases (55) · Mandibular Diseases (55) · Muscular Diseases (55) · Stomatognathic Diseases (54) · Craniomandibular Disorders (53) · Musculoskeletal Diseases (53) · Pathological Conditions, Signs and Symptoms (21) · Signs and Symptoms (19) · Neurologic Manifestations (18) · Pain (10) · Nervous System Diseases (9) · Behavior (5) · Neuromuscular Diseases (4) · Digestive System Diseases (2)
Musculoskeletal Manipulations (4) · Occlusal Splints (4) · Acupuncture Therapy (2) · Botulinum Toxins, Type A (2) · Counseling (2) · Dental Care (2) · Dry Needling (2) · Exercise Therapy (2) · Patient Education as Topic (2) · Splints (2) · Air (1) · Arthrocentesis (1) · Ascorbic Acid (1) · Denture, Complete (1) · Exercise (1)
Hasan Kalyoncu University (3) · Cairo University (2) · Croatian Science Foundation (2) · Hacettepe University (2) · Karolinska Institutet (2) · University Medicine Greifswald (2) · University of Sao Paulo (2) · Abant Izzet Baysal University (1) · Alexandria University (1) · Ankara Yildirim Beyazıt University (1) · Ascentia Health, Inc. (1) · Beijing Hospital of Traditional Chinese Medicine (1) · Capnia, Inc. (1) · Cardenal Herrera University (1) · Dental Practice-Based Research Network (1)
Brazil (9) · Turkey (Türkiye) (8) · United States (6) · Croatia (3) · Egypt (3) · Germany (3) · Poland (3) · Spain (3) · China (2) · Sweden (2) · Canada (1) · France (1) · Italy (1) · Japan (1) · Malaysia (1)
Alejandro Tsuchiya, DDS (1) · Aysenur Tuncer, PhD (1) · Dominique Chauvel-Lebret (1) · Edward L. Truelove, DDS, MSD (1) · Eric Schiffman, DDS (1) · Gabriel PL Almeida, MSc (1) · Gaby M Bleichhardt, Dr. (PhD) (1) · Georg Meyer, Prof. (1) · Georg Meyer, Prof. Dr. (1)
PMID 11005733, PMID 12756930, PMID 12836501, PMID 1298767, PMID 15179561, PMID 15635556, PMID 15829878, PMID 16040444, PMID 16873325, PMID 17717958, PMID 18976268, PMID 20001836, PMID 21457291, PMID 22623334, PMID 22916669, PMID 22980538, PMID 23446073, PMID 23672400, PMID 23869629, PMID 24080932, PMID 24482784, PMID 25889823, PMID 26040190, PMID 26622281, PMID 26634569, PMID 28013436, PMID 29269980, PMID 29623141, PMID 29939051, PMID 30523705, PMID 31170954, PMID 31325122, PMID 31722951, PMID 32297945, PMID 32533874, PMID 32620810, PMID 32701836, PMID 33030089, PMID 33529226, PMID 33560875, PMID 33797785, PMID 33884400, PMID 34022805, PMID 34488856, PMID 35254961, PMID 35546396, PMID 35939919, PMID 36220481, PMID 36484668, PMID 37451727
2005 (1), U01DE016747 (1), U01DE024169 (1), U19AT004663 (1)