7 unknown, 5 recruiting, 5 terminated, 4 completed. 26 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 26 | Unknown 7, Recruiting 5, Terminated 5, Completed 4, Enrolling by invitation 2, Not yet recruiting 2, Active not recruiting 1 |
Follow Systemic Vasculitis: new trials by email Literature Review of Systemic Vasculitis trials Research Report on Systemic Vasculitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases Dengue 1,2,3,4 (attenuated) vaccine - Rheumatoid Arthritis (RA), Juvenile Idiopathic Arthritis (JIA) | Phase 4 | Recruiting | University of Sao Paulo General Hospital | 477 | 2026-03-16 | 2026-07-20 |
| Comparison of a Strategy Based on Clinico-biological Monitoring Versus Pre-emptive Rituximab Treatment in Cases of ANCA Reappearance in Granulomatosis With Polyangiitis and Microscopic Polyangiitis. Rituximab - ANCA Associated Vasculitis (AAV), Polyangiitis (GPA) | Phase 4 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 70 | 2026-02-01 | 2026-03-05 |
| Beyond EOsinophils: proteoMICS to Identify Potential Biomarker of Organ Damage and Response to MEPOLIZUMAB in EGPA Mepolizumab 100 MG Injection [Nucala], Mepolizumab 300 mg - EGPA - Eosinophilic Granulomatosis With Polyangiitis, Severe Asthma | Phase 4 | Enrolling by invitation | Azienda Ospedaliero Universitaria di Cagliari | 90 | 2025-10-17 | 2026-01-15 |
| SGLT-2 Inhibitors on Albuminuria in Chronic Kidney Disease Patients With Lupus Nephritis and ANCA- Associated Vasculitis Gliflozin - Lupus Nephritis (LN), ANCA Associated Vasculitis (AAV) | Phase 4 | Not yet recruiting | Federico II University | 40 | 2025-09-01 | 2025-06-25 |
| Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic Diseases Shingrix, vaccination with 2 doses of Shingrix vaccine - Systemic Vasculitis, Spondylarthropathies | Phase 4 | Enrolling by invitation | Region Skane | 240 | 2024-12-17 | 2025-01-10 |
| Avacopan vs Reduced-dose Glucocorticoids in ANCA-associated Vasculitis Avacopan, prednisolone and rituximab, Prednisolone and rituximab - ANCA Associated Vasculitis (AAV) | Phase 4 | Recruiting | Chiba University | 160 | 2024-11-15 | 2025-05-04 |
| A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis Avacopan, Placebo, Standard of Care - Antineutrophil Cytoplasmic Antibody-associated Vasculitis | Phase 4 | Recruiting | Amgen | 300 | 2024-02-07 | 2026-09-30 |
| Efficacy and Safety for Rituximab Combined With Telitacicept in the Treatment of ANCA-associated Vasculitis (TTCAAVREM) Telitacicept, Placebo of Telitacicept - ANCA Associated Vasculitis | Phase 4 | Recruiting | Chinese SLE Treatment And Research Group | 40 | 2023-06-29 | 2023-07-27 |
| Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases Recombinant Herpes Zoster Vaccine (RZV), MTX Discontinuation, MMF Discontinuation - Rheumatoid Arthritis, Spondylitis, Ankylosing | Phase 4 | Active not recruiting | University of Sao Paulo General Hospital | 2005 | 2023-05-23 | 2026-05-04 |
| Efficacy and Safety for Telitacicept in the Remission Maintenance Treatment of ANCA-associated Vasculitis (TTCAZAREM) Azathioprine, Telitacicept - ANCA-associated Vasculitis, Maintenance Therapy | Phase 4 | Recruiting | Chinese SLE Treatment And Research Group | 40 | 2023-03-09 | 2023-07-28 |
| Stratified Therapy on Pediatric AAGN GlucoCorticoid - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, ANCA-Associated Glomerulonephritis | Phase 4 | Unknown | Wang Mo | 200 | 2023-01-01 | 2023-08-01 |
| Comparison of Tofacitinib and Methotrexate in the Maintained Treatment of GPA Tofacitinib, Methotrexate - Granulomatosis With Polyangiitis | Phase 4 | Unknown | Shanghai Zhongshan Hospital | 66 | 2021-07-01 | 2021-07-09 |
| Hydroxychloroquine in ANCA Vasculitis Evaluation Hydroxychloroquine, Placebo - ANCA Associated Vasculitis, Microscopic Polyangiitis | Phase 4 | Terminated | Guy's and St Thomas' NHS Foundation Trust | 43 | 2020-12-17 | 2026-04-29 |
| Combined Pneumococcal Conjugate and Polysaccharide Vaccination in Inflammatory Rheumatic Disease 13-valent pneumococcal conjugate vaccine, 23-valent pneumococcal polysaccharide vaccine - Rheumatoid Arthritis, Systemic Lupus | Phase 4 | Completed | Region Skane | 300 | 2016-06-14 | 2023-03-29 |
| Maintenance of ANCA Vasculitis Remission by Intermittent Rituximab Dosing Rituximab - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Phase 4 | Terminated | Massachusetts General Hospital | 115 | 2016-06-01 | 2023-07-27 |
| Rituximab for the Otolaryngologic Manifestations of Granulomatosis With Polyangiitis Rituximab, Placebo - Granulomatosis With Polyangiitis (Wegener's Granulomatosis) | Phase 4 | Terminated | Hospital for Special Surgery, New York | 3 | 2015-12-01 | 2018-03-22 |
| A Study Evaluating the Safety and Efficacy of Rituximab in Combination With Glucocorticoids in Participants With Wegener's Granulomatosis or Microscopic Polyangitis Methylprednisolone, Prednisone, Rituximab - Wegener's Granulomatosis or Microscopic Polyangiitis | Phase 4 | Completed | Hoffmann-La Roche | 30 | 2015-07-06 | 2022-07-06 |
| Low-dose Glucocorticoid Vasculitis Induction Study Rituximab, Glucocorticoids - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Microscopic Polyangiitis | Phase 4 | Unknown | Chiba University | 140 | 2014-10-01 | 2021-01-27 |
| Pilot Study of Short-Course Glucocorticoids and Rituximab for Treatment of ANCA-Associated Vasculitis Glucocorticoids, Rituximab - Granulomatosis With Polyangiitis, Microscopic Polyangiitis | Phase 4 | Completed | Massachusetts General Hospital | 20 | 2014-06-01 | 2021-06-25 |
| Alemtuzumab for ANCA Associated Refractory Vasculitis Alemtuzumab - Vasculitis, Microscopic Polyangiitis | Phase 4 | Unknown | Cambridge University Hospitals NHS Foundation Trust | 24 | 2011-02-01 | 2011-07-29 |
Showing 20 of 26. Sign in to see all of them.
Granulomatosis with Polyangiitis (13) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (11) · Microscopic Polyangiitis (10) · Vasculitis (5) · Arthritis, Juvenile (4) · Arthritis, Rheumatoid (4) · Churg-Strauss Syndrome (4) · Lupus Erythematosus, Systemic (3) · Scleroderma, Systemic (3) · Sjogren's Syndrome (3) · Spondylarthritis (3) · Antiphospholipid Syndrome (2) · Arthritis, Psoriatic (2) · Dermatomyositis (2)
Autoimmune Diseases (26) · Cardiovascular Diseases (26) · Immune System Diseases (26) · Skin and Connective Tissue Diseases (26) · Vascular Diseases (26) · Skin Diseases (25) · Skin Diseases, Vascular (24) · Vasculitis (21) · Respiratory Tract Diseases (15) · Lung Diseases (14) · Lung Diseases, Interstitial (13) · Nervous System Diseases (13) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (11) · Brain Diseases (11)
Rituximab (8) · Azathioprine (5) · Cyclophosphamide (4) · Glucocorticoids (3) · Prednisone (3) · Methotrexate (2) · Methylprednisolone (2) · Prednisolone (2) · avacopan (2) · telitacicept (2) · 13-valent pneumococcal vaccine (1) · 23-valent pneumococcal capsular polysaccharide vaccine (1) · Alemtuzumab (1) · Cryoelectron Microscopy (1) · Cryosurgery (1)
Assistance Publique - Hôpitaux de Paris (2) · Chiba University (2) · Chinese SLE Treatment And Research Group (2) · Hospices Civils de Lyon (2) · Massachusetts General Hospital (2) · Region Skane (2) · University of Sao Paulo General Hospital (2) · Amgen (1) · Azienda Ospedaliero Universitaria di Cagliari (1) · CSA Medical, Inc. (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Federico II University (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Hoffmann-La Roche (1) · Hospital for Special Surgery, New York (1)
United States (5) · China (4) · Brazil (3) · France (2) · Japan (2) · Switzerland (2) · United Kingdom (2) · Czechia (1) · Denmark (1) · Greece (1) · Hungary (1) · India (1) · Italy (1) · Netherlands (1) · Poland (1)
Coen A Stegeman, MD, PhD (1) · David D'Cruz (1) · David RW Jayne, MD MRCP (1) · Hiroshi Nakajima, M.D., Ph.D (1) · JIng Li, M.D. (1) · Jehns Martineus, MD (1) · Jing Li, MD (1) · John H Stone, MD (1) · John L Niles, MD (1) · Lindi Jiang, PhD (1)
PMID 25153486, PMID 34061144, PMID 18240234, PMID 19054820, PMID 21540203, PMID 21859696, PMID 22089462, PMID 22298793, PMID 22908326, PMID 22931582, PMID 22949223, PMID 22992045, PMID 23045170, PMID 23123020, PMID 23525305, PMID 23590801, PMID 23818263, PMID 24961747, PMID 25693055, PMID 27242368, PMID 28968874, PMID 29247107, PMID 32087733, PMID 33164993, PMID 33596356, PMID 35110332, PMID 35110333, PMID 35365179, PMID 36927642, PMID 37024906, PMID 37734880, PMID 38123922, PMID 41679320, PMID 41932224, PMID 42261247, PMID 42294825, PMID 42843284, PMID 9041949
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