9 completed, 3 recruiting, 2 not yet recruiting, 2 unknown. 8 Not applicable, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 5, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 2 | 2 | Recruiting 2 |
| Phase 1 | 1 | Active not recruiting 1 |
Follow Syringomyelia: new trials by email Literature Review of Syringomyelia trials Research Report on Syringomyelia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Abnormality of the Central Canal of the Spinal Cord in Syringomyelia in a Patient With a Basal Skull Malformation MRI - Chiari Malformation Type I, Syringomyelia | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 50 | 2026-09-30 | 2026-07-22 |
| Extracellular Vesicles for the Treatment of Syringomyelia Exosomes group - Syringomyelia | Phase 1 | Active not recruiting | Xuanwu Hospital, Beijing | 18 | 2025-12-23 | 2026-06-30 |
| Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis in Spinal Arachnoiditis and Syringomyelia Subarachnoid-Subarachnoid (S-S) Bypass, Intradural Adhesion Lysis - Syringomyelia | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 200 | 2024-04-01 | 2024-04-19 |
| The Therapeutic Effect of Betaine in Syringomyelia Betaine, Placebo - Syringomyelia | Phase 2 | Recruiting | Xuanwu Hospital, Beijing | 30 | 2024-03-01 | 2024-03-13 |
| The Therapeutic Effect of Thalidomide in Syringomyelia Thalidomide - Syringomyelia, Thalidomide | Phase 2 | Recruiting | Xuanwu Hospital, Beijing | 30 | 2024-02-01 | 2024-02-20 |
| PFDD Versus PFDRT in Chiari Decompression Surgery Posterior fossa decompression with duraplasty, PFDD with tonsillar resection/reduction - Chiari Malformation Type I, Tonsillectomy | Not applicable | Completed | Xuanwu Hospital, Beijing | 250 | 2024-01-31 | 2026-02-17 |
| Development of a Patient-reported Outcome Measure for Chiari Malformation and Syringomyelia focus groups, questionnaire - Syringomyelia, Chiari Malformation | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 60 | 2023-09-01 | 2023-09-21 | |
| Impact of Peripheral Afferent Input on Central Neuropathic Pain Lidocaine (10 mg/ml), Isotonic saline - Spinal Cord Injuries, Spinal Cord Diseases | Not applicable | Unknown | University of Aarhus | 20 | 2022-12-01 | 2022-12-12 |
| Identification of Genetic Mutations Involved in Chiari Type I Malformations Blood Sample - Chiari Malformation, Type 1 | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 40 | 2022-06-15 | 2026-03-17 |
| Clinical Outcome in Patients With Syringomyelia（COPSM） high throughput sequencing and electromyography - Syringomyelia/Hydromyelia | Unknown | Xuanwu Hospital, Beijing | 200 | 2021-04-16 | 2021-06-08 | |
| Investigation of the Effects of Exercise on Patients With Chiari Malformation Motor learning based exercise - Chiari Malformation Type I, Proprioceptive Disorders | Not applicable | Completed | Hacettepe University | 16 | 2020-07-06 | 2021-01-26 |
| Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia Posterior fossa decompression, Dural Augmentation - Arnold-Chiari Malformation, Type 1, Chiari Malformation Type I | Not applicable | Completed | Washington University School of Medicine | 162 | 2016-04-01 | 2024-10-31 |
| Clinical Trial of a Serious Game for Individuals With SCI/D SCI Hard - Spinal Cord Injury, Spinal Cord Involvement | Not applicable | Completed | University of Michigan | 184 | 2015-02-05 | 2019-02-22 |
| A Prospective Natural History Study of Patients With Syringomyelia Syringomyelia, Arnold Chiari Deformity | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 180 | 2010-08-03 | 2026-10-26 | |
| Genetic Analysis of the Chiari I Malformation Syringomyelia, Type I Arnold Chiari Malformation | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 152 | 2001-06-04 | 2026-10-29 | |
| Study and Surgical Treatment of Syringomyelia Syringomyelia | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 50 | 2001-02-08 | 2017-07-02 | |
| Establishing the Physiology of Syringomyelia Arnold Chiari Deformity, Hydrocephalus | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 120 | 1992-07-29 | 2017-07-02 |
Arnold-Chiari Malformation (9) · Spinal Cord Injuries (3) · Spinal Cord Diseases (2) · Arachnoiditis (1) · Behavior (1) · Cone-Rod Dystrophies (1) · Hydrocephalus (1) · Meningitis (1) · Mucopolysaccharidosis IV (1) · Myelitis, Transverse (1) · Neuralgia (1) · Paralysis (1) · Postpoliomyelitis Syndrome (1) · Somatosensory Disorders (1)
Central Nervous System Diseases (17) · Nervous System Diseases (17) · Spinal Cord Diseases (15) · Congenital Abnormalities (10) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (10) · Nervous System Malformations (10) · Neural Tube Defects (10) · Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Trauma, Nervous System (3) · Wounds and Injuries (3) · Bone Diseases (2) · Genetic Diseases, Inborn (2) · Musculoskeletal Diseases (2)
Betaine (1) · Blood Specimen Collection (1) · Electromyography (1) · Focus Groups (1) · Surveys and Questionnaires (1) · Thalidomide (1)
Xuanwu Hospital, Beijing (6) · National Institute of Neurological Disorders and Stroke (NINDS) (4) · Assistance Publique - Hôpitaux de Paris (2) · Hacettepe University (1) · University Hospital, Bordeaux (1) · University of Aarhus (1) · University of Michigan (1) · Washington University School of Medicine (1)
China (6) · United States (6) · France (3) · Russia (1) · Turkey (Türkiye) (1)
John D Heiss, M.D. (2) · David D Limbrick, MD, PhD (1) · Fengzeng Jian, M.D. (1) · Jan Rosner, MD (1) · Michelle A Meade, PhD (1) · Steven Knafo (1)
PMID 38014747, PMID 23082850, PMID 32805463, PMID 36424067, PMID 37248485, PMID 22958075, PMID 22978540, PMID 32114543, PMID 42080534, PMID 42202320