66 completed. 66 Phase 2, 6 Phase 3, 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 66 | Completed 66 |
| Phase 3 | 6 | Completed 6 |
| Phase 1 | 5 | Completed 5 |
Follow Stomatitis: new trials by email Literature Review of Stomatitis trials Research Report on Stomatitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Arginine- and Glutamine-based Oral Formulations on Salivary Biomarkers and Clinical Severity of Radiation-induced Oral Mucositis in Head and Neck Cancer: A Randomized Controlled Trial L-arginine Oral Suspension, L-glutamine Oral Suspension, Maltodextrin Oral Suspension (Control) - Radiation Induced Oral Mucositis, Oral Mucositis | Phase 2 | Completed | Ain Shams University | 84 | 2025-04-01 | 2026-01-30 |
| Efficacy and Safety of Acyclovir-penciclovir Cream Versus an Abreva in the Suppression of Herpes Simplex Virus Eruptions acyclovir-penciclovir cream, Abreva - Herpes Simplex Oral | Phase 2 | Completed | University of Utah | 58 | 2024-08-19 | 2026-10-27 |
| A Lithium-containing Mouthwash Prevention and Treatment of Oral Mucositis and Dysgeusia in Patients Undergoing Radiotherapy lithium-containing mouthwash （Phase I）, Plcacebo mouthwash （Phase II）, lithium-containing mouthwash（Phase II） - Head and Neck Squamous Cell Carcinoma, Malignant Head and Neck Tumors | Phase 1 / Phase 2 | Completed | West China Hospital | 175 | 2024-03-01 | 2026-08-13 |
| Lactobacillus Rhamnosus GG Alleviates Oral Mucositis in Patients Undergoing Radiotherapy Lactobacillus rhamnosus GG, Placebo-containing tablets, Radiotherapy - Oral Mucositis | Phase 2 | Completed | West China Hospital | 160 | 2023-11-10 | 2026-09-09 |
| Omega-3 Hydrogel and Prevention of Oral Mucositis topical oral Omega-3 hydrogel, conventional preventive treatment - Mucositis Oral | Phase 2 / Phase 3 | Completed | Basma Morsy | 36 | 2022-02-09 | 2023-01-31 |
| EDTA Eye Drops Compared to Abreva for Herpes Simplex Virus Eruptions EDTA, Abreva - Herpes Simplex Oral | Phase 2 | Completed | University of Utah | 10 | 2022-01-20 | 2025-10-31 |
| Streptococcus Salivarius K12 for Prevention and Treatment of Oral Mucositis in Patients Undergoing Radiotherapy Streptococcus salivarius K12, Streptococcus salivarius K12 simulants - Head and Neck Squamous Cell Carcinoma | Phase 2 | Completed | West China Hospital | 160 | 2022-01-01 | 2024-02-05 |
| Propolis-based Product (FARINGEL PLUS) for Oral Mucositis in Palliative Care Faringel plus and oral hygiene - Oral Mucositis | Phase 2 | Completed | Campus Bio-Medico University | 77 | 2021-07-13 | 2023-02-08 |
| Ph 2 Open Label Study of GC4419 to Reduce SOM Associated With Chemoradiotherapy for Head and Neck Cancer Drug: GC4419, Intensity-modulated radiation therapy (IMRT), Cisplatin - Head and Neck Cancer, Oral Mucositis | Phase 2 | Completed | Galera Therapeutics, Inc. | 38 | 2020-06-30 | 2022-08-16 |
| MOM's PAIN (Methylene Blue for Oral Mucositis' PAIN) Best Practice, Methylene Blue - Malignant Neoplasm, Oral Pain | Phase 2 | Completed | M.D. Anderson Cancer Center | 69 | 2019-02-28 | 2023-04-25 |
| L Brevis for Traumatic Oral Lesions in Orthodontic Patients L brevis, Placebo - Orthodontic Appliance Complication, Oral Mucositis | Phase 2 | Completed | Universidade de Passo Fundo | 20 | 2019-01-07 | 2020-05-21 |
| Safety and Efficacy of RRx-001 in the Attenuation of Oral Mucositis in Patients Receiving Chemoradiation for the Treatment of Oral Cancers RRx-001, Cisplatin for injection, Radiation Therapy - Oral Mucositis | Phase 2 | Completed | EpicentRx, Inc. | 53 | 2018-07-12 | 2024-11-04 |
| EC-18 for Oral Mucositis in Patients With Concomitant Chemoirradiation EC-18, Placebo - Stomatitis | Phase 2 | Completed | Enzychem Lifesciences Corporation | 105 | 2018-07-03 | 2023-07-27 |
| Melatonin for Prevention of Radiation Induced Oral Mucositis Rapid Release Capsules Melatonin, 10 mg, Miconaz oral gel, BBC oral spray - Oral Mucositis (Ulcerative) Due to Radiation | Phase 2 | Completed | Hams Hamed Abdelrahman | 40 | 2018-01-12 | 2019-06-17 |
| Effectiveness and Safety of Lactobacillus Rhamnosus Lcr35® in the Treatment of Recurrent Aphthous Stomatitis Bacilor, Placebo - Aphthous Stomatitis | Phase 2 | Completed | Centre Hospitalier Universitaire de Nice | 20 | 2018-01-04 | 2026-03-24 |
| Folic Acid Supplement Versus Placebo for Treating Mucositis Adverse Events in Metastatic Renal Cell Carcinoma Patients Receiving Targeted Therapy Folic Acid, Placebo Oral Tablet - Mucositis, Stomatitis | Phase 2 | Completed | Niels Fristrup | 84 | 2017-12-20 | 2026-09-23 |
| Evaluation of ONCOXIN® in Oral Mucositis, Appetite and Body Mass in Cancer Patients. Oncoxin® - Mucositis Oral | Phase 2 | Completed | Catalysis SL | 15 | 2017-11-01 | 2018-08-01 |
| Effect of Oral Vitamin C in Assessing the Severity of Oral Mucositis in Chemoradiation of Head and Neck Cancers Ascorbic Acid, Zinc acetate - Oral Mucositis | Phase 2 / Phase 3 | Completed | Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre | 180 | 2016-08-01 | 2019-03-20 |
| Supersaturated Calcium Phosphate Oral Rinse (Caphosol®) For the Prevention of Oral Mucositis in Children Undergoing Chemotherapeutic Treatments Caphosol, 0,9% NaCl - Cancer | Phase 2 | Completed | Tampere University Hospital | 47 | 2016-08-01 | 2020-02-20 |
| Should We Use Oral Valacyclovir in Acute Herpetic Gingivostomatitis in Children? Valacyclovir, placebo - Herpetic Gingivostomatitis | Phase 2 | Completed | St. Justine's Hospital | 80 | 2016-07-01 | 2023-04-11 |
Showing 20 of 66. Sign in to see all of them.
Head and Neck Neoplasms (12) · Mucositis (12) · Stomatitis, Aphthous (9) · Neoplasms (5) · Stomatitis, Herpetic (5) · Oral Ulcer (4) · Squamous Cell Carcinoma of Head and Neck (4) · Stomatitis, Denture (4) · Mouth Diseases (3) · Acquired Immunodeficiency Syndrome (2) · Candidiasis, Oral (2) · HIV Infections (2) · Herpes Labialis (2) · Herpes Simplex (2)
Stomatognathic Diseases (66) · Mouth Diseases (63) · Neoplasms (18) · Neoplasms by Site (18) · Digestive System Diseases (13) · Gastrointestinal Diseases (13) · Gastroenteritis (12) · Infections (10) · Virus Diseases (7) · Neoplasms by Histologic Type (6) · Skin Diseases (6) · Skin and Connective Tissue Diseases (6) · DNA Virus Infections (5) · Herpesviridae Infections (5)
Cisplatin (4) · Fibroblast Growth Factor 7 (3) · Ascorbic Acid (2) · Diphenhydramine (2) · FGF20 protein, human (2) · Injections (2) · Nystatin (2) · Radiotherapy (2) · Radiotherapy, Intensity-Modulated (2) · Thalidomide (2) · Water (2) · avasopasem manganese (2) · docosanol (2) · Anthocyanins (1) · Celecoxib (1)
Kerman University of Medical Sciences (3) · M.D. Anderson Cancer Center (3) · Qazvin University Of Medical Sciences (3) · West China Hospital (3) · Beech Tree Labs, Inc. (2) · CuraGen Corporation (2) · Galera Therapeutics, Inc. (2) · University of Utah (2) · Access Pharmaceuticals, Inc. (1) · Ain Shams University (1) · All India Institute of Medical Sciences (1) · Amgen (1) · Basma Morsy (1) · Biotec Pharmacon ASA (1) · Campus Bio-Medico University (1)
United States (28) · Iran (5) · Canada (4) · India (4) · China (3) · Egypt (3) · Germany (3) · Spain (3) · France (2) · Israel (2) · Italy (2) · Puerto Rico (2) · Switzerland (2) · Belgium (1) · Brazil (1)
Christopher M Hull, M.D. (2) · Xingchen Peng (2) · Alicia Lozano, MD (1) · Andy Trotti, MD (1) · Anet Tanic, DDS (1) · Atul Sharma, MD,DM (1) · Brian M Feldman, MD, MSc (1) · Bryan Oronsky, MD, PhD (1) · Carlos Roldan (1) · Christopher M Nutting, Dr.med. (1) · Donald Welsh, MD (1) · Dong Moon Shin, MD (1)
PMID 35142535, PMID 18413833, PMID 18973181, PMID 19733615, PMID 20855800, PMID 21741230, PMID 25151488, PMID 28335798, PMID 28848667, PMID 31101577, PMID 31954066, PMID 32725875, PMID 33831097, PMID 35007812, PMID 35435039, PMID 35724774, PMID 36324139, PMID 36551677, PMID 36640725, PMID 39711194, PMID 40197962, PMID 40604730, PMID 42347702
K23DE016946 (1), R21CA158530 (1)