2 withdrawn, 1 active not recruiting, 1 available, 1 not yet recruiting. 2 Phase 2, 1 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Withdrawn 2 |
| Not applicable | 1 | Not yet recruiting 1 |
| Phase 1 | 1 | Active not recruiting 1 |
Follow Spindle Cell Sarcoma: new trials by email Literature Review of Spindle Cell Sarcoma trials Research Report on Spindle Cell Sarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Chest CT Versus Chest X-Ray for Lung Surveillance After Curative-Intent Resection of High-Risk Truncal-Extremity Soft Tissue Sarcoma Biopsy, Chest Computed Tomography, Chest Radiography - Adult Pleomorphic Rhabdomyosarcoma, AJCC Grade 2 Sarcoma | Not applicable | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 1582 | 2025-01-28 | 2024-07-30 |
| Phase 2 Study of 9-ING-41 With Chemotherapy in Sarcoma Gemcitabine, 9-ING-41, Docetaxel - Soft Tissue Sarcoma, Undifferentiated Pleomorphic Sarcoma | Phase 2 | Withdrawn | Brown University | 2022-03-01 | 2021-12-07 | |
| A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With Advanced Sarcomas Gemcitabine, Docetaxel, 9-ING-41 - Sarcoma, Soft Tissue Sarcoma | Phase 2 | Withdrawn | Brown University | 2021-09-01 | 2021-07-28 | |
| Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma Definitive Surgical Resection, Nanoplexed Poly I:C BO-112, Nivolumab - Leiomyosarcoma, Malignant Peripheral Nerve Sheath Tumor | Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 14 | 2020-10-14 | 2026-03-10 |
| Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients AVM0703, Hydrocortisone, Proton pump inhibitor - Glioblastoma, Squamous Cell Carcinoma | Available | AVM Biotechnology Inc | 2025-10-02 | |||
| Tazemetostat Expanded Access Program for Adults With Solid Tumors Tazemetostat - Epithelioid Sarcoma (Ex-US Only), Spindle Cell Sarcoma | No longer available | Epizyme, Inc. | 2026-07-02 |
Sarcoma (6) · Sarcoma, Synovial (5) · Dermatofibrosarcoma (4) · Histiocytoma, Malignant Fibrous (4) · Leiomyosarcoma (4) · Hemangiosarcoma (3) · Liposarcoma (3) · Bone Neoplasms (2) · Neurofibrosarcoma (2) · Rhabdomyosarcoma (2) · Brain Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Renal Cell (1) · Carcinoma, Squamous Cell (1) · Chondrosarcoma (1)
Neoplasms by Histologic Type (6) · Neoplasms, Connective and Soft Tissue (6) · Neoplasms (5) · Neoplasms, Connective Tissue (5) · Histiocytoma (4) · Neoplasms by Site (4) · Neoplasms, Fibrous Tissue (4) · Neoplasms, Muscle Tissue (4) · Fibrosarcoma (3) · Neoplasms, Adipose Tissue (3) · Neoplasms, Nerve Tissue (3) · Neoplasms, Vascular Tissue (3) · Nervous System Diseases (3) · Nervous System Neoplasms (3) · Bone Diseases (2)
3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-(1,3)dioxolo(4,5-f)indol-7-yl)-pyrrole-2,5-dione (2) · Docetaxel (2) · Gemcitabine (2) · BO-112 (1) · Biopsy (1) · Hydrocortisone (1) · Nivolumab (1) · Proton Pump Inhibitors (1) · Radiation (1) · Radiotherapy (1) · X-Rays (1) · tazemetostat (1)
Brown University (2) · AVM Biotechnology Inc (1) · ECOG-ACRIN Cancer Research Group (1) · Epizyme, Inc. (1) · Jonsson Comprehensive Cancer Center (1)
United States (3)
Bradley D DeNardo, MD (1) · Bradley DeNardo, MD (1) · Don S Dizon, MD (1) · Edward Loniewski, D.O. (1) · Galina G Lagos, MD (1) · Kenneth Cardona (1) · Vishruth Reddy, MD, PhD (1)
K08CA245181 (1), UG1CA189828 (1)