3 recruiting, 2 completed, 2 terminated. 7 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Recruiting 3, Completed 2, Terminated 2 |
| Phase 2 | 4 | Recruiting 2, Completed 1, Terminated 1 |
Follow Spasticity: new trials by email Literature Review of Spasticity trials Research Report on Spasticity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Use of Photobiomodulation in the Treatment of Spasticity After Stroke. Photobiomodulation Therapy, Placebo PBM, Standard Multidisciplinary Rehabilitation Program for Spasticity - Stroke, Spasticity | Phase 1 / Phase 2 | Recruiting | University of Nove de Julho | 42 | 2026-08-28 | 2026-09-01 |
| Shockwave for Elbow and Wrist Spasticity in People With Spinal Cord Injury Focused extracorporeal shockwave therapy - Spinal Cord Injury, Spasticity | Phase 1 | Recruiting | Kessler Foundation | 12 | 2026-03-06 | 2026-10-22 |
| A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity. Corabotase, Placebo, Dysport - Spasticity | Phase 1 / Phase 2 | Recruiting | Ipsen | 240 | 2021-04-29 | 2026-07-28 |
| Shockwaves Therapy and Botulinum Toxin for the Treatment of Spasticity in Patients With Cerebral Palsy. A Cross Over RCT shock waves, Botulinum Toxin Type A - Spasticity, Cerebral Palsy | Phase 1 | Completed | Xavi Vidal Novellas | 70 | 2014-09-01 | 2017-03-13 |
| Oral Baclofen Pharmacokinetics and Pharmacodynamics in Children With Spasticity baclofen - Spasticity, Cerebral Palsy | Phase 1 / Phase 2 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 61 | 2008-11-01 | 2011-12-06 |
| One Year Extension Study To Protocol C2/5/TZ:MS-05 sublingual tizanidine 12 mg - Spasticity, Multiple Sclerosis | Phase 1 / Phase 2 | Terminated | Teva GTC | 10 | 2008-01-01 | 2009-02-19 |
| Botox vs. Baclofen for Upper Limb Spasticity intramuscular Botox versus oral baclofen - Spasticity | Phase 1 | Terminated | Vanderbilt University | 8 | 2006-02-01 | 2012-01-20 |
Muscle Spasticity (7) · Cerebral Palsy (2) · Brain Injuries, Traumatic (1) · Fatigue (1) · Multiple Sclerosis (1) · Spinal Cord Injuries (1) · Stroke (1)
Muscle Hypertonia (7) · Muscular Diseases (7) · Musculoskeletal Diseases (7) · Nervous System Diseases (7) · Neurologic Manifestations (7) · Neuromuscular Manifestations (7) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Central Nervous System Diseases (5) · Brain Diseases (4) · Brain Damage, Chronic (2) · Trauma, Nervous System (2) · Wounds and Injuries (2) · Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1)
Baclofen (1) · Botulinum Toxins, Type A (1) · Low-Level Light Therapy (1) · abobotulinumtoxinA (1)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Ipsen (1) · Kessler Foundation (1) · Teva GTC (1) · University of Nove de Julho (1) · Vanderbilt University (1) · Xavi Vidal Novellas (1)
United States (4) · Spain (2) · Austria (1) · Brazil (1) · Bulgaria (1) · Czechia (1) · France (1) · Germany (1) · Hungary (1) · Israel (1) · Italy (1) · Japan (1) · Poland (1) · Portugal (1) · Russia (1)
Arnon Karni, MD (1) · Janice Brunstrom, MD (1) · P. David Charles, MD (1) · Richard Stevenson, MD (1) · Vidal Novellas (1)