1153 completed, 329 unknown, 164 recruiting, 163 terminated. 2029 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 2029 | Completed 1153, Unknown 329, Recruiting 164, Terminated 163, Not yet recruiting 89, Withdrawn 76, Active not recruiting 44, Enrolling by invitation 11 |
Follow Skin and Connective Tissue Diseases: new trials by email Literature Review of Skin and Connective Tissue Diseases trials Research Report on Skin and Connective Tissue Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients Skin Cleanser Combination No.1 - Atopic Dermatitis | Phase 4 | Not yet recruiting | Boston Children's Hospital | 100 | 2031-01-01 | 2026-03-10 |
| Suzetrigine Versus Standard Analgesia After Skin Cancer Surgery Suzetrigine, Acetaminophen Plus Ibuprofen - Postoperative Pain, Acute Pain | Phase 4 | Not yet recruiting | University of Minnesota | 230 | 2027-04-01 | 2026-09-25 |
| Evaluation of the Efficacy and Acceptability of a Phytotherapy Combining Devil's Claw, Blackcurrant and Meadowsweet for the Management of Aromatase Inhibitor-induced Arthralgia in Patients Treated for Localized Breast Cancer in the Adjuvant Setting Phytotherapy Dietary Supplement (Harpagophytum, Meadowsweet, and Blackcurrant), Patient Experience Questionnaire - Hormone Therapy-induced Arthralgia, Phytotherapy | Phase 4 | Not yet recruiting | Hospices Civils de Lyon | 105 | 2027-01-01 | 2026-11-03 |
| Opzelura Experience Study ruxolitinib, ruxolitinib and an Eczema Action Plan - Atopic Dermatitis | Phase 4 | Not yet recruiting | Wake Forest University Health Sciences | 50 | 2026-12-01 | 2026-09-04 |
| Comparative Efficacy of Luliconazole and Bifonazole Combined With Itraconazole in Dermatophytosis Itraconazole, Luliconazole Cream 1%, Bifonazole cream 1% - Tinea Corporis,Tinea Cruris,Tinea Faciei | Phase 4 | Not yet recruiting | University of Faisalabad | 182 | 2026-12-01 | 2026-11-05 |
| A Study to Assess the Safety, and Tolerability of Nivolumab + Relatlimab Fixed-Dose Combination (FDC) In Unresectable or Metastatic Melanoma Participants In India Nivolumab + Relatlimab - Unresectable Melanoma, Metastatic Melanoma | Phase 4 | Not yet recruiting | Bristol-Myers Squibb | 40 | 2026-11-15 | 2026-08-12 |
| AD Treatment Optimization With Ebglyss in Real-World Practice: A Multicenter Study of Patient-Centered Outcomes Lebrikizumab-lbkz - Atopic Dermatitis | Phase 4 | Not yet recruiting | Forefront Dermatology S.C | 250 | 2026-11-11 | 2026-10-02 |
| Withdrawal Versus Continued TNF Inhibitor Monotherapy Treatment in Children With Inactive Juvenile Idiopathic Arthritis Adalimumab, Etanercept, Golimumab - Juvenile Idiopathic Arthritis (JIA) | Phase 4 | Not yet recruiting | Oslo University Hospital | 90 | 2026-11-11 | 2026-10-29 |
| Baseline Dermoscopic Vascular Score and Response to Oral Tranexamic Acid in Facial Melasma Tranexamic acid, Standardised sunscreen and emollient - Melasma | Phase 4 | Not yet recruiting | Allied Hospital Faisalabad | 128 | 2026-11-01 | 2026-10-19 |
| Clascoterone Versus Clindamycin Added to Adapalene/Benzoyl Peroxide for Moderate Facial Acne Clascoterone 1% cream, Clindamycin 1% lotion, Adapalene 0.1%/benzoyl peroxide 2.5% gel - Acne Vulgaris | Phase 4 | Not yet recruiting | Allied Hospital Faisalabad | 118 | 2026-11-01 | 2026-10-19 |
| Phase 4 Master Protocol for Patients Prescribed Prademagene Zamikeracel for the Treatment of Wounds Non-conforming pz-cel surgical application to RDEB wounds, Additional biopsies, Pz-cel surgical application to DEB wounds - Epidermolysis Bullosa (EB), Recessive Dystrophic Epidermolysis Bullosa (RDEB) | Phase 4 | Not yet recruiting | Abeona Therapeutics, Inc | 100 | 2026-11-01 | 2026-08-06 |
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| FES PET/MRI for Occult Disease in Lobular Breast Cancer 18Fluoroestradiol (18F-FES), MRI, Gadolinium-based contrast agent (GBCA) - Lobular Breast Carcinoma | Phase 4 | Not yet recruiting | University of Wisconsin, Madison | 30 | 2026-11-01 | 2026-11-03 |
| A Study to Investigate Dupixent/ Dupilumab in Adult Indian Participants With Moderate-to-severe Atopic Dermatitis Dupilumab - Atopic Dermatitis | Phase 4 | Not yet recruiting | Sanofi | 56 | 2026-10-28 | 2026-10-29 |
| Microneedling-Assisted Metformin, Tranexamic Acid, and Modified Kligman's Formula for Melasma Metformin 30% Topical Lotion, Tranexamic Acid 0.5% Topical Solution, Modified Kligman's Formula - Melasma (Facial Melasma) | Phase 4 | Enrolling by invitation | Sameh Sarsik | 80 | 2026-10-25 | 2026-10-27 |
| Seltoplasmid Plus Revascularization for Diabetic Infrapopliteal Chronic Limb-Threatening Ischemia Lower-Extremity Revascularization, Donaperminogene Seltoplasmid - Chronic Limb-Threatening Ischemia, Diabetic Foot Ulcer | Phase 4 | Not yet recruiting | First Affiliated Hospital of Wenzhou Medical University | 180 | 2026-10-20 | 2026-09-18 |
| Efficacy and Safety of Triple-Combination Cream Plus Microneedling Along With Tranexamic Acid Versus Platelet-Rich Plasma in the Treatment of Moderate-to-Severe Melasma: A Randomized Comparative Study Group B (Triple Combination Cream + Microneedling + Platelet-Rich Plasma) - Melasma (Facial Melasma) | Phase 4 | Active not recruiting | Bangladesh Medical University | 60 | 2026-10-13 | 2026-10-23 |
| Bimzelx (Bimekizumab) For The Treatment Of Adult Onset Pityriasis Rubra Pilaris (PRP) Bimekizumab - Pityriasis Rubra Pilaris | Phase 4 | Not yet recruiting | Mayo Clinic | 12 | 2026-10-01 | 2026-09-08 |
| A Study of QL1706 Combined With OH2 Injection in Perioperative Treatment of Stage III Resectable Acral Melanoma Iparomlimab and Tuvonralimab Injection (QL1706), OH2 Injection(Recombinant Human GM-CSF Oncolytic Type II Herpes Simplex Virus) - Melanoma, Acral Melanoma | Phase 4 | Not yet recruiting | Peking University Cancer Hospital & Institute | 76 | 2026-10-01 | 2026-10-02 |
| Comparison of Itraconazole With Itraconazole and Isotretinoin in the Treatment Duration, Safety a n d Cure Rate in Adult Patients of Tinea Corporis/ Cruris-A Randomised Controlled Trail Itraconazole (200 mg), ISOtretinoin 20 MG - Tinea Corporis | Phase 4 | Not yet recruiting | Pak Emirates Military Hospital | 60 | 2026-10-01 | 2026-06-30 |
Showing 20 of 2029. Sign in to see all of them.
Arthritis, Rheumatoid (325) · Breast Neoplasms (280) · Psoriasis (184) · Dermatitis, Atopic (136) · Acne Vulgaris (121) · Lupus Erythematosus, Systemic (57) · Diabetic Foot (55) · Arthritis, Psoriatic (48) · Keratosis, Actinic (46) · Pruritus (33) · Eczema (29) · Lupus Nephritis (29) · Osteoarthritis (28) · Skin Diseases (28) · Melanoma (27)
Skin Diseases (1479) · Immune System Diseases (703) · Connective Tissue Diseases (565) · Autoimmune Diseases (467) · Musculoskeletal Diseases (467) · Joint Diseases (412) · Neoplasms (396) · Arthritis (391) · Rheumatic Diseases (369) · Neoplasms by Site (327) · Pathological Conditions, Signs and Symptoms (321) · Breast Diseases (289) · Skin Diseases, Papulosquamous (250) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (227)
Methotrexate (114) · Etanercept (83) · Adalimumab (82) · tocilizumab (43) · Rituximab (33) · Tacrolimus (33) · Gels (30) · Standard of Care (30) · dupilumab (30) · Infliximab (29) · tofacitinib (28) · Adapalene (26) · Sodium Chloride (26) · Abatacept (24) · Prednisone (24)
Hoffmann-La Roche (43) · Galderma R&D (39) · Assiut University (28) · Novartis Pharmaceuticals (28) · Amgen (26) · Pfizer (23) · Ottawa Hospital Research Institute (21) · Stiefel, a GSK Company (21) · Cairo University (17) · Novartis (17) · University of California, San Francisco (17) · Wyeth is now a wholly owned subsidiary of Pfizer (16) · DePuy International (14) · Peking Union Medical College Hospital (14) · Sanofi (14)
United States (697) · China (169) · Germany (121) · Canada (118) · France (117) · United Kingdom (106) · Spain (90) · Italy (84) · Netherlands (79) · Egypt (72) · Brazil (56) · South Korea (55) · Belgium (53) · Denmark (51) · India (46)
Ronald W Gottschalk, MD (9) · Robert Bissonnette, MD (8) · Herbert B Slade, MD (7)
PMID 38979716, PMID 19935134, PMID 22882561, PMID 25913550, PMID 26982791, PMID 27338778, PMID 28924971, PMID 29951993, PMID 30415588, PMID 31277720, PMID 33687069, PMID 15389191, PMID 18050189, PMID 20684151, PMID 22150039, PMID 24907147, PMID 25071111, PMID 25153486, PMID 25359382, PMID 25889222, PMID 26348120, PMID 26438146, PMID 26729950, PMID 27432356, PMID 27432417, PMID 28255449, PMID 28376912, PMID 28532759, PMID 28814431, PMID 29448838, PMID 29450636, PMID 29776990, PMID 30243803, PMID 32025629, PMID 33283264, PMID 34061144, PMID 36600185, PMID 36601090, PMID 36931693, PMID 39192350, PMID 42261247, PMID 42694939, PMID 42825996, PMID 10233295, PMID 1052771, PMID 10536559, PMID 10607349, PMID 10642676, PMID 10865927, PMID 10951254
2008 (12), 2016 (11), 2015 (10), 2018 (10), 2023 (10), 2014 (9), 2005 (7), 2009 (7), 2025 (7), 2004 (6), 2017 (5), 2019 (5), 1RC1DK086182 (1), 1RC1HD063312-01 (1), K23AI070078 (1)