4 not yet recruiting. 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Not yet recruiting 4 |
Follow Scleroderma, Diffuse: new trials by email Literature Review of Scleroderma, Diffuse trials Research Report on Scleroderma, Diffuse
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Systemic Sclerosis (SSc) Refractory to Standard Therapy C-CAR168 - Systemic Sclerosis (SSc), Systemic Sclerosis | Phase 1 | Not yet recruiting | AbelZeta Inc. | 12 | 2027-03-01 | 2026-10-13 |
| A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases BMS-986553 - Systemic Lupus Erythematosus, Sjögren's Disease | Phase 1 | Not yet recruiting | Bristol-Myers Squibb | 60 | 2026-10-30 | 2026-10-14 |
| Allogeneic CD19/BCMA-Targeted CAR-γδT Cell Therapy: Safety and Preliminary Pharmacodynamics in Relapsed/Refractory Autoimmune Diseases Allogeneic CD19/BCMA-targeted CAR-γδT cell injection, Cyclophosphamide, Fludarabine - Refractory/Relapsed Systemic Lupus Erythematosus, Refractory / Relapsed / Progressive Systemic Sclerosis | Phase 1 | Not yet recruiting | Institute of Hematology & Blood Diseases Hospital, China | 9 | 2026-07-01 | 2026-06-09 |
| YTS109 in Pediatric Relapsed/Refractory Autoimmune Diseases YTS109 cell - Systemic Lupus Erythematosus (SLE), Diffuse Systemic Sclerosis | Phase 1 | Not yet recruiting | Children's Hospital of Fudan University | 12 | 2026-03-01 | 2026-02-27 |
Lupus Erythematosus, Systemic (3) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (2) · Autoimmune Diseases (2) · Myositis (2) · Scleroderma, Systemic (2) · Sjogren's Syndrome (2) · Antiphospholipid Syndrome (1) · Arthritis, Rheumatoid (1) · Dermatomyositis (1) · Dry Eye Syndromes (1) · Lung Diseases, Interstitial (1) · Lupus Nephritis (1) · Recurrence (1)
Connective Tissue Diseases (4) · Immune System Diseases (4) · Skin Diseases (4) · Skin and Connective Tissue Diseases (4) · Arthritis (2) · Autoimmune Diseases (2) · Cardiovascular Diseases (2) · Eye Diseases (2) · Joint Diseases (2) · Lacrimal Apparatus Diseases (2) · Mouth Diseases (2) · Muscular Diseases (2) · Musculoskeletal Diseases (2) · Nervous System Diseases (2) · Neuromuscular Diseases (2)
Cyclophosphamide (1) · fludarabine (1)
AbelZeta Inc. (1) · Bristol-Myers Squibb (1) · Children's Hospital of Fudan University (1) · Institute of Hematology & Blood Diseases Hospital, China (1)
United States (2) · Belgium (1) · China (1) · France (1) · Germany (1) · Netherlands (1) · Poland (1)
Yihong Yao, PhD (1)