17 completed. 17 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 17 | Completed 17 |
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 1 | Completed 1 |
Follow Sarcoma, Soft Tissue: new trials by email Literature Review of Sarcoma, Soft Tissue trials Research Report on Sarcoma, Soft Tissue
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma Dexrazoxane, Doxorubicin - Sarcoma, Soft Tissue, Soft Tissue Sarcoma | Phase 2 | Completed | Washington University School of Medicine | 73 | 2016-02-22 | 2023-11-07 |
| Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapy Pazopanib - Sarcoma, Soft Tissue, Soft Tissue Sarcoma | Phase 2 | Completed | Washington University School of Medicine | 56 | 2015-04-08 | 2020-08-05 |
| Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors nab-paclitaxel - Neuroblastoma, Rhabdomyosarcoma | Phase 1 / Phase 2 | Completed | Celgene | 107 | 2013-12-04 | 2019-12-27 |
| A Study of Olaratumab in Soft Tissue Sarcoma Olaratumab, doxorubicin - Sarcoma, Soft Tissue | Phase 1 / Phase 2 | Completed | Eli Lilly and Company | 148 | 2010-10-01 | 2017-04-14 |
| A Study of LY573636-Sodium in the Treatment of Patients With Metastatic Soft Tissue Sarcoma LY573636-sodium - Sarcoma, Soft Tissue | Phase 2 | Completed | Eli Lilly and Company | 101 | 2007-08-01 | 2019-09-18 |
| BAY-43-9006 in Advanced, Metastatic Soft Tissue Sarcomas Sorafenib (BAY-43-9006) - Sarcoma, Soft Tissue | Phase 2 | Completed | Istituto Clinico Humanitas | 69 | 2006-11-01 | 2010-09-02 |
| TLC D-99 and Ifosfamide in Metastatic Soft Tissue Sarcoma Patients combination of TLC D-99 and Ifosfamide - Sarcoma, Soft Tissue | Phase 1 / Phase 2 | Completed | Istituto Clinico Humanitas | 36 | 2006-09-01 | 2009-12-18 |
| Chemotherapy Drug Sensitivity Microculture (MiCK) Assay for Apoptosis Laboratory Assay, Mick Assay - Breast Neoplasms, Lung Neoplasms | Phase 2 / Phase 3 | Completed | Pierian Biosciences | 150 | 2006-09-01 | 2012-01-26 |
| Pazopanib In Patients With Relapsed Or Refractory Soft Tissue Sarcoma pazopanib - Sarcoma, Soft Tissue | Phase 2 | Completed | GlaxoSmithKline | 148 | 2005-11-01 | 2016-02-03 |
| Alimta Plus Gemcitabine for Advanced Sarcoma Alimta, Gemcitabine - Sarcoma, Soft Tissue | Phase 2 | Completed | Columbia University | 12 | 2005-08-01 | 2020-08-25 |
| a Multicenter Clinical Trial for the Treatment of Children and Adolescents With Soft Tissue Sarcoma Stage 4 Topotecan, Carboplatin - Sarcoma, Soft Tissue | Phase 2 | Completed | Cooperative Weichteilsarkom Study Group | 90 | 2005-01-01 | 2009-04-02 |
| Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED) ridaforolimus - Leiomyosarcoma, Liposarcoma | Phase 2 | Completed | Merck Sharp & Dohme LLC | 216 | 2004-10-01 | 2015-02-13 |
| Evaluation of Side Effects and Relative Activity of Two Chemotherapy Regimens in the Treatment Soft Tissue Sarcoma ifosfamide and doxorubicin vs gemcitabine and docetaxel - Sarcoma, Soft Tissue | Phase 2 | Completed | University of Michigan Rogel Cancer Center | 84 | 2004-08-01 | 2015-12-07 |
| Study Evaluating the Safety and Efficacy of ABT-510 in Subjects With Locally Advanced or Metastatic Soft Tissue Sarcoma ABT-510 - Thrombospondin-1 mimetic - Sarcoma, Soft Tissue | Phase 2 | Completed | Abbott | 88 | 2003-05-01 | 2007-11-29 |
| Study of Gemcitabine and Vinorelbine in Soft Tissue Sarcomas gemcitabine, vinorelbine - Sarcoma, Soft Tissue | Phase 2 | Completed | Dana-Farber Cancer Institute | 40 | 2003-02-01 | 2007-12-21 |
| Bendamustin Hydrochloride in Patients With Soft Tissue Sarcoma (STS) Bendamustin - Sarcoma, Soft Tissue | Phase 2 | Completed | University Hospital Tuebingen | 28 | 2002-03-01 | 2007-04-20 |
| Neoadjuvant Adriamycin and Ifosfamide Plus High-Dose ICE in Patients With Soft Tissue Sarcoma (STS) Adriamycin, Ifosfamide, Etoposide - Sarcoma, Soft Tissue | Phase 2 | Completed | University Hospital Tuebingen | 1999-02-01 | 2007-04-20 |
Sarcoma (17) · Leiomyosarcoma (3) · Dermatofibrosarcoma (2) · Fibrosarcoma (2) · Liposarcoma (2) · Osteosarcoma (2) · Sarcoma, Synovial (2) · Breast Neoplasms (1) · Hemangiosarcoma (1) · Histiocytoma (1) · Histiocytoma, Malignant Fibrous (1) · Lung Neoplasms (1) · Melanoma (1) · Neoplasm Metastasis (1) · Neoplasms (1)
Neoplasms by Histologic Type (17) · Neoplasms, Connective and Soft Tissue (17) · Neoplasms (16) · Neoplasms, Connective Tissue (4) · Neoplasms, Muscle Tissue (4) · Neoplasms by Site (2) · Neoplasms, Adipose Tissue (2) · Neoplasms, Bone Tissue (2) · Neoplasms, Fibrous Tissue (2) · Neoplasms, Nerve Tissue (2) · Skin Diseases (2) · Skin and Connective Tissue Diseases (2) · Adnexal Diseases (1) · Breast Diseases (1) · Endocrine Gland Neoplasms (1)
Doxorubicin (3) · Ifosfamide (3) · Carboplatin (2) · Gemcitabine (2) · pazopanib (2) · 130-nm albumin-bound paclitaxel (1) · Albumin-Bound Paclitaxel (1) · Bendamustine Hydrochloride (1) · Dexrazoxane (1) · Docetaxel (1) · Drug Therapy (1) · Etoposide (1) · N-((5-bromo-2-thienyl)sulfonyl)-2,4-dichlorobenzamide (1) · Pemetrexed (1) · Razoxane (1)
Eli Lilly and Company (2) · Istituto Clinico Humanitas (2) · University Hospital Tuebingen (2) · Washington University School of Medicine (2) · Abbott (1) · Celgene (1) · Columbia University (1) · Cooperative Weichteilsarkom Study Group (1) · Dana-Farber Cancer Institute (1) · GlaxoSmithKline (1) · Merck Sharp & Dohme LLC (1) · Pierian Biosciences (1) · University of Michigan Rogel Cancer Center (1)
United States (10) · Germany (3) · Italy (3) · France (2) · Spain (2) · United Kingdom (2) · Argentina (1) · Belgium (1) · Canada (1) · Hungary (1) · Netherlands (1) · Switzerland (1)
Armando Santoro, MD (2) · Brian A Van Tine, M.D., Ph.D. (2) · Alexander Zweibach, MD, PhD (1) · Cary Presant, MD (1) · Ileana Elias, M.D. (1) · Joerg T Hartmann, MD (1) · Joerg T. Hartmann, MD (1) · Karl Rogers, MD (1) · Pat Whitworth, MD (1) · Robert N Taub, MD, PhD (1) · Rod Humerickhouse, MD (1) · Scott Schuetze, MD, PhD (1) · Suzanne George, MD (1)
PMID 22067397, PMID 22539091, PMID 24504442, PMID 27291997, PMID 27544129, PMID 31401903, PMID 32554315
2004 (1)