167 completed, 23 unknown, 11 recruiting, 9 withdrawn. 56 Not applicable, 56 Phase 2, 38 Phase 3, 27 Phase 1, 27 Phase 4.
Follow Rosacea: new trials by email Literature Review of Rosacea trials Research Report on Rosacea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dermocosmetic Treatment for Facial Redness in Rosacea With or Without Laser Therapy Dermocosmetic tested product, Placebo, Vascular laser treatment - Rosacea, Erythematotelangiectatic, Rosacea Subtype 1 (Erythematotelangiectatic) | Not applicable | Recruiting | ISISPHARMA | 50 | 2026-09-03 | 2026-09-08 |
| Abdominal Symptoms and Rosacea: An Observational Study on the Association Between Irritable Bowel Syndrome (IBS) and the Gut-Skin Axis IBS (Irritable Bowel Syndrome), Rosacea | Recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 300 | 2026-09-01 | 2026-11-06 | |
| A Phase 2 Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib (LOU064) in Adult Patients With Papulopustular Rosacea (PPR) LOU064, Placebo - Papulopustular Rosacea | Phase 2 | Recruiting | Novartis Pharmaceuticals | 100 | 2026-07-30 | 2026-11-10 |
| Transcutaneous Auricular Vagus Nerve Stimulation Treatment for Rosacea Transaricular vagus nerve stimulation (taVNS) - Rosacea, Rosacea, Erythematotelangiectatic | Not applicable | Recruiting | Brigham and Women's Hospital | 10 | 2026-05-23 | 2026-08-14 |
| Skin Inflammation in (Peri)Menopause: A Probiotic Intervention Proof of Concept Trial Lactobacillus casei Shirota (LcS) Probiotic Drink, Skimmed Milk Control Drink - Skin Inflammation, Immunosenescence | Not applicable | Recruiting | King's College London | 30 | 2026-04-28 | 2026-05-08 |
| The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow Light Therapy) Combined With Tofacitinib and Doxycycline in Chinese Adult Patients With Mild to Moderate Erythematous Telangiectatic Rosacea Doxycycline, Hydroxychloroquine, Tofacitinib - Erythematotelangiectatic Rosacea | Not applicable | Recruiting | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 186 | 2026-02-01 | 2026-03-24 |
| Acupuncture for Refractory Rosacea: A Study on Its Effectiveness and Safety Acupuncture, Sham Acupuncture - Rosacea | Not applicable | Recruiting | Xiangya Hospital of Central South University | 104 | 2025-12-24 | 2026-01-30 |
| Vbeam Pro Pulse Dye Laser for the Treatment of Vascular Conditions Vbeam Pro Laser Treatment - Rosacea, Vascular Diseases | Not applicable | Enrolling by invitation | Candela Corporation | 40 | 2025-12-10 | 2026-11-02 |
| A Study Comparing Ivermectin Cream 1%, Soolantra™ Cream 1%, PrROSIVER® Cream1% to Placebo Control in the Treatment of Moderate to Severe Facial Rosacea. Ivermectin Cream 1%, Soolantra™ Cream 1%, PrRosiver® Cream 1% - Rosacea | Phase 1 | Completed | Sun Pharmaceutical Industries, Inc. | 865 | 2025-12-09 | 2026-08-31 |
| Study of Lotilaner Ophthalmic Gel in Patients With Ocular Rosacea (KORE) lotilaner, Vehicle - Ocular Rosacea | Phase 2 | Enrolling by invitation | Tarsus Pharmaceuticals, Inc. | 155 | 2025-12-05 | 2026-03-02 |
| Real-World Study of Crisugabalin(HSK16149) for the Treatment of Rosacea Crisugabalin(HSK16149)20mg BID, Crisugabalin(HSK16149) 20mg qd - Rosacea | Not applicable | Completed | The First Affiliated Hospital with Nanjing Medical University | 30 | 2025-10-29 | 2026-07-21 |
| Microfocused Ultrasound for Facial Pigmentary Diseases and Rosacea Microfocused Ultrasound Treatment, Sham Microfocused Ultrasound Stimulation - Melasma, Rosacea | Not applicable | Active not recruiting | Xiangya Hospital of Central South University | 200 | 2025-10-01 | 2026-06-30 |
| Efficacy of IPL, an Anti-redness Dermocosmetic, and Their Combination in the Treatment of Rosacea Intense Pulsed Light (IPL) - Lumecca, Rosacure anti-redness dermocosmetic regimen - Rosacea | Not applicable | Completed | Medical University of Silesia | 60 | 2025-09-29 | 2026-07-27 |
| Brimonidine 0.33% for Rosacea-Related Facial Erythema Brimonidine 0.33% gel, Placebo gel - Rosacea, Rosacea Subtype 1 (Erythematotelangiectatic) | Phase 4 | Completed | Istanbul Training and Research Hospital | 45 | 2025-05-01 | 2026-02-24 |
| Efficacy and Safety of Topical Clascoterone (WINLEVI) Cream 1% in Patients With Facial Acneiform Rosacea Clascoterone Cream 1% - Papular-pustular Rosacea, Papulopustular Rosacea (PPR) | Phase 2 | Recruiting | Narrows Institute for Biomedical Research | 20 | 2025-03-14 | 2025-05-06 |
| Analysis of Factors Associated With the Efficacy of 595-nm Pulsed Dye Laser Treatment for Rosacea pulse duration, 6ms, pulse duration, 10ms - Pulsed Dye Laser, Rosacea | Not applicable | Completed | The First Affiliated Hospital with Nanjing Medical University | 80 | 2025-02-01 | 2026-02-17 |
| Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermatosis Face mask containing Centella sinensis - Rosacea, Acne | Not applicable | Not yet recruiting | Nanjing First Hospital, Nanjing Medical University | 30 | 2025-01-08 | 2025-01-08 |
| Comparative Study of Low-Energy 1064nm Laser and DPL in Rosacea Treatment DPL - Rosacea | Not applicable | Completed | Second Affiliated Hospital of Xi'an Jiaotong University | 31 | 2024-12-07 | 2025-05-20 |
| Rosacea Radiofrequency Microneedling KTP Laser Therapy, Radiofrequency microneedling - Rosacea, Papulopustular, Rosacea, Erythematotelangiectatic | Not applicable | Recruiting | University of Miami | 20 | 2024-11-01 | 2026-07-24 |
| Deucravacitinib Rosacea Deucravacitinib, Placebo - Papulopustular Rosacea | Phase 2 | Withdrawn | Icahn School of Medicine at Mount Sinai | 2024-11-01 | 2025-01-24 |
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Erythema (16) · Acne Vulgaris (13) · Telangiectasis (9) · Dermatitis, Atopic (8) · Psoriasis (5) · Dermatitis, Seborrheic (4) · Skin Diseases (4) · Alopecia Areata (3) · Dry Eye Syndromes (3) · Eczema (3) · Flushing (3) · Hidradenitis Suppurativa (3) · Meibomian Gland Dysfunction (3) · Melanosis (3)
Skin and Connective Tissue Diseases (223) · Skin Diseases (219) · Pathological Conditions, Signs and Symptoms (22) · Signs and Symptoms (18) · Skin Manifestations (18) · Sebaceous Gland Diseases (14) · Acneiform Eruptions (13) · Cardiovascular Diseases (12) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (12) · Skin Diseases, Eczematous (11) · Vascular Diseases (11) · Genetic Diseases, Inborn (10) · Dermatitis (9) · Eye Diseases (9) · Hypersensitivity (9)
Doxycycline (18) · azelaic acid (15) · Gels (11) · Ivermectin (9) · Metronidazole (8) · Brimonidine Tartrate (6) · Omiganan (4) · Oxymetazoline (4) · Minocycline (3) · Sodium Chloride (3) · Botulinum Toxins, Type A (2) · Calcium Dobesilate (2) · Capsules (2) · Hydroxychloroquine (2) · Rifaximin (2)
Galderma R&D (24) · LEO Pharma (8) · Allergan (7) · Maruho Co., Ltd. (5) · Sol-Gel Technologies, Ltd. (5) · Actavis Inc. (4) · Padagis LLC (4) · Sun Pharmaceutical Industries, Inc. (4) · CAGE Bio Inc. (3) · CollaGenex Pharmaceuticals (3) · Istanbul Training and Research Hospital (3) · Journey Medical Corporation (3) · Mayo Clinic (3) · National Taiwan University Hospital (3) · Second Affiliated Hospital of Xi'an Jiaotong University (3)
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Ronald W Gottschalk, MD (5) · Michael Graeber, MD (4) · Angela Moore, MD (3) · Andrew Pollack, MD (2) · Dow Stough, MD (2) · Fran Cook-Bolden, MD (2) · Girish Munavalli, MD (2) · Joseph Fowler, MD (2) · Kappa Meadows, MD (2) · Kimberly Grande, MD (2) · Mark Ling, MD (2) · Martin Steinhoff, MD (2)
PMID 34840653, PMID 35491738, PMID 37636253, PMID 38822948, PMID 40042869, PMID 10906647, PMID 15661816, PMID 18071725, PMID 20645521, PMID 21699130, PMID 22076328, PMID 22395584, PMID 23233252, PMID 23455486, PMID 23839181, PMID 24993600, PMID 25007365, PMID 25142778, PMID 25548852, PMID 26244354, PMID 26416154, PMID 26916576, PMID 27183026, PMID 27235002, PMID 27272077, PMID 27424017, PMID 27459457, PMID 27718519, PMID 27861741, PMID 27885682, PMID 28095550, PMID 28213875, PMID 28541265, PMID 28686772, PMID 29082084, PMID 29089180, PMID 29091565, PMID 29396702, PMID 29566276, PMID 29611306, PMID 30658871, PMID 30730346, PMID 30794364, PMID 31392722, PMID 31880327, PMID 32360760, PMID 32819957, PMID 32989925, PMID 33536740, PMID 33548303
2017 (1), 2025 (1), R15AR069912 (1)