25 completed, 1 active not recruiting, 1 recruiting, 1 unknown. 10 Phase 4, 6 Phase 3, 4 Not applicable, 4 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Completed 10 |
| Phase 3 | 6 | Completed 6 |
| Not applicable | 4 | Completed 3, Unknown 1 |
| Phase 2 | 4 | Completed 4 |
| Phase 1 | 3 | Completed 2, Recruiting 1 |
| Early Phase 1 | 1 | Active not recruiting 1 |
Follow azelaic acid: new trials by email Literature Review of azelaic acid trials Research Report on azelaic acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of a Combined Topical Formula Versus Placebo in Patients With Melasma Topical azelaic acid 12% plus tranexamic acid 5%, Placebo topical formulation - Melasma | Not applicable | Completed | University of Guadalajara | 40 | 2026-06-12 | 2026-07-27 |
| Study to Evaluate the Feasibility of Twice Daily Use of Topical Azelaic Acid in Breast Cancer Patients Undergoing Radiation Azelaic Acid - Breast Cancer | Phase 1 | Recruiting | Virginia Commonwealth University | 33 | 2025-08-13 | 2026-07-14 |
| Azelaic Acid 20% vs Hydroquinone 4% in Epidermal Melasma Topical Azelaic Acid 20% Cream, Topical 4% hydroquinone cream - Melasma, Melasma (Facial Melasma) | Not applicable | Completed | Gujranwala medical college District Headquarters Hospital, Gujranwala | 146 | 2025-05-04 | 2026-01-08 |
| Azelaic Acid as a Novel Treatment for Central Centrifugal Cicatricial Alopecia (CCCA) azelaic acid, usual medication for CCCA - Central Centrifugal Cicatricial Alopecia | Early Phase 1 | Active not recruiting | Wake Forest University Health Sciences | 18 | 2024-08-12 | 2026-07-01 |
| To Evaluate the Therapeutic Equivalence and Safety in Treatment of Moderate Facial Rosacea Azelaic acid foam 15%, Finacea® (Azelaic acid Foam) 15%, Vehicle of the test product - Rosacea | Phase 1 | Completed | Sun Pharmaceutical Industries, Inc. | 1116 | 2017-12-12 | 2019-03-19 |
| Azelaic Acid Foam 15% in the Treatment of Papulopustular Rosacea Azelaic Acid foam 15% - Rosacea, Papulopustular | Phase 4 | Completed | Clinical Research Center of the Carolinas | 5 | 2017-12-06 | 2019-07-24 |
| A Study of Patient Concerns and Treatment Satisfaction in Patients Being Treated With Finacea Foam for Rosacea Azelaic Acid (Finacea Foam, BAY39-6251) - Rosacea | Completed | LEO Pharma | 2200 | 2017-07-20 | 2020-04-01 | |
| A Study to Evaluate Safety and Equivalence of Generic Azelaic Acid Foam and Finacea® Foam in Participants With Rosacea Generic Azelaic Acid Foam, Finacea® (Azelaic Acid) Foam, Vehicle Foam - Rosacea | Phase 3 | Completed | Actavis Inc. | 924 | 2016-07-19 | 2019-07-31 |
| To Evaluate the Therapeutic Equivalence and Safety of Azelaic Acid 15% Topical Gel Azelaic Acid 15% topical gel, Finacea® (azelaic acid) Gel, 15%, Placebo - Rosacea | Phase 1 | Completed | Sun Pharmaceutical Industries, Inc. | 1000 | 2016-07-01 | 2024-04-10 |
| Finacea 15% and Brimonidine 0.33% Gel in the Treatment of Rosacea - A Pilot Study Azelaic acid 15%, Brimonidine 0.33% - Acne Rosacea | Phase 4 | Completed | Derm Research, PLLC | 22 | 2014-05-01 | 2015-09-30 |
| Comparison of the Efficacy and Safety of Clindamycin + Benzoyl Peroxide Formulation With Azelaic Acid Formulation in the Treatment of Acne Vulgaris Clindamycin + BPO, Azelaic acid - Acne Vulgaris | Phase 4 | Completed | GlaxoSmithKline | 222 | 2014-02-21 | 2017-08-25 |
| A Study to Evaluate the Safety and Clinical Study of Azelaic Acid Gel 15% in Patients With Moderate Facial Rosacea Azelaic acid, Vehicle, Finacea - Rosacea | Phase 3 | Completed | Actavis Inc. | 1009 | 2013-07-01 | 2020-06-02 |
| The Influence of Peripheral Androgen Conversion at Women Adult Acne treatment azelaic acid (azelan), dorspirenone/ethynil estradiol - Acne, Quality of Life | Not applicable | Unknown | Marco Alexandre Dias da Rocha | 60 | 2012-03-01 | 2013-05-09 |
| Phase 3 Papulopustular Rosacea Study CD5024, Azelaic acid 15% Gel - Papulopustular Rosacea | Phase 3 | Completed | Galderma R&D | 688 | 2011-12-01 | 2021-02-18 |
| Phase 3 Papulopustular Rosacea Study CD5024, Azelaic acid 15% Gel - Papulopustular Rosacea (PPR) | Phase 3 | Completed | Galderma R&D | 683 | 2011-12-01 | 2021-02-18 |
| Study for Long-term Treatment of Acne Vulgaris With Skinoren Versus Differin skinoren, differin - Acne Vulgaris | Phase 4 | Completed | University of Magdeburg | 60 | 2011-08-01 | 2013-07-08 |
| Azelaic Acid on Demodex Counts in Rosacea Azelaic acid - Rosacea | Phase 2 / Phase 3 | Completed | Wake Forest University | 20 | 2010-12-01 | 2018-09-07 |
| Combination Gel and Vascular ND in Mild to Moderate Rosacea Azelaic acid, Nd:Yag laser - Rosacea | Not applicable | Completed | Wake Forest University Health Sciences | 10 | 2010-07-01 | 2018-09-12 |
| Split-face Tolerability Comparison Between MetroGel® 1% vs Finacea® 15% in Subjects With Healthy Skin metronidazole 1% gel, azelaic acid 15% gel - Skin Manifestations | Phase 4 | Completed | Galderma R&D | 77 | 2010-06-01 | 2022-08-01 |
| Split-Face Tolerability Comparison Between MetroGel® 1% Versus Finacea® 15% in Subjects With Healthy Skin metronidazole 1% gel, azelaic acid 15% gel - Skin Manifestations | Phase 4 | Completed | Galderma R&D | 80 | 2010-06-01 | 2022-08-01 |
Showing 20 of 28. Sign in to see all of them.
Rosacea (15) · Acne Vulgaris (5) · Hyperpigmentation (3) · Melanosis (2) · Skin Manifestations (2) · Breast Neoplasms (1) · Dermatitis, Perioral (1)
LEO Pharma (7) · Galderma R&D (4) · Actavis Inc. (2) · Derm Research, PLLC (2) · Sun Pharmaceutical Industries, Inc. (2) · Wake Forest University Health Sciences (2) · Clinical Research Center of the Carolinas (1) · Dermatology Specialists Research (1) · GlaxoSmithKline (1) · Gujranwala medical college District Headquarters Hospital, Gujranwala (1) · Marco Alexandre Dias da Rocha (1) · University of Guadalajara (1) · University of Magdeburg (1) · Virginia Commonwealth University (1) · Wake Forest University (1)
United States (19) · Germany (5) · Canada (2) · Brazil (1) · Mexico (1) · Pakistan (1)
Leon H. Kircik, M.D. (2) · Michael Graeber, M.D. (2) · Ronald W Gottschalk, MD (2) · Alan Fleischer, MD (1) · Amy J McMichael, MD (1) · Amy McMichael, MD (1) · Anja Thielitz, Dr. med. (1) · James M Jackson, MD (1) · John Capicchioni (1) · Natalie Yantovskiy (1) · Todd C. Adams, MD (1)