24 completed, 2 withdrawn, 1 unknown. 27 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 27 | Completed 24, Withdrawn 2, Unknown 1 |
| Phase 2 | 7 | Completed 5, Withdrawn 2 |
Follow Rosacea: new trials by email Literature Review of Rosacea trials Research Report on Rosacea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Comparing Ivermectin Cream 1%, Soolantra™ Cream 1%, PrROSIVER® Cream1% to Placebo Control in the Treatment of Moderate to Severe Facial Rosacea. Ivermectin Cream 1%, Soolantra™ Cream 1%, PrRosiver® Cream 1% - Rosacea | Phase 1 | Completed | Sun Pharmaceutical Industries, Inc. | 865 | 2025-12-09 | 2026-08-31 |
| Bioequivalence Study of Ivermectin 1% Cream and Soolantra (Ivermectin) 10 mg/g Cream Ivermectin cream, Soolantra ® (Ivermectin) cream - Rosacea | Phase 1 | Completed | Humanis Saglık Anonim Sirketi | 44 | 2024-03-06 | 2024-08-20 |
| Efficacy and Safety of Different Dose Regimens of Gabapentin for Treating Erythema/Flushing in Rosacea: A Randomized Controlled Trial minocycline combined with hydroxychloroquine, gabapentin 300mg bid, gabapentin 300mg tid - Rosacea, Rosacea Subtype 1 (Erythematotelangiectatic) | Phase 1 | Completed | First Affiliated Hospital of Chongqing Medical University | 50 | 2024-01-05 | 2026-01-05 |
| Study to Evaluate the Safety of ATR-04 ATR-04, Placebo - Epidermal Growth Factor, Papulopustular Rosacea | Phase 1 / Phase 2 | Withdrawn | Azitra Inc. | 2024-01-01 | 2025-10-03 | |
| Effectivity and Safety of Metronidazole 1% Cream in Rosacea Therapy Metronidazole 1% Cream,Top, Placebo - Rosacea | Phase 1 | Unknown | Dr.dr.Irma Bernadette, SpKK (K) | 48 | 2023-05-01 | 2023-05-16 |
| Impact of DFD-29 on Microbial Flora of Healthy, Adult Human Subjects When Administered Over 16 Weeks Minocycline hydrochloride capsules, Placebo - Rosacea | Phase 1 | Completed | Journey Medical Corporation | 60 | 2022-09-30 | 2023-08-02 |
| Topical Mitogenic-Activated Protein Kinase (MAPK) Inhibition in Rosacea Trametinib - Rosacea, Erythematotelangiectatic | Phase 1 | Completed | Albany Research Institute, Inc. | 12 | 2021-11-01 | 2023-05-30 |
| A Safety and Efficacy Study to Evaluate Rosacea AIV001, Vehicle - Papulopustular Rosacea | Phase 1 / Phase 2 | Withdrawn | AiViva BioPharma, Inc. | 2021-07-01 | 2024-12-17 | |
| Evaluation of Topical Encapsulated Benzoyl Peroxide on the Skin Microbiome and Skin Biophysical Properties Encapsulated Benzoyl Peroxide Cream - Papulopustular Rosacea | Phase 1 | Completed | Sol-Gel Technologies, Ltd. | 31 | 2020-06-10 | 2023-04-18 |
| CGB-400 for the Reduction of Facial Redness CGB-400 - Rosacea | Phase 1 | Completed | CAGE Bio Inc. | 25 | 2018-10-26 | 2020-08-11 |
| CGB-400 for the Reduction of Facial Redness and Bumps and Blemishes CGB-400 - Rosacea | Phase 1 | Completed | CAGE Bio Inc. | 27 | 2018-10-26 | 2020-08-12 |
| To Evaluate the Therapeutic Equivalence and Safety in Treatment of Moderate Facial Rosacea Azelaic acid foam 15%, Finacea® (Azelaic acid Foam) 15%, Vehicle of the test product - Rosacea | Phase 1 | Completed | Sun Pharmaceutical Industries, Inc. | 1116 | 2017-12-12 | 2019-03-19 |
| Open Label Study to Assess the Effect of Secukinumab in Moderate to Severe Papulopustular Rosacea Secukinumab - Papulopustular Rosacea | Phase 1 / Phase 2 | Completed | Anne Chang | 24 | 2017-06-21 | 2020-02-05 |
| To Evaluate the Therapeutic Equivalence and Safety of Azelaic Acid 15% Topical Gel Azelaic Acid 15% topical gel, Finacea® (azelaic acid) Gel, 15%, Placebo - Rosacea | Phase 1 | Completed | Sun Pharmaceutical Industries, Inc. | 1000 | 2016-07-01 | 2024-04-10 |
| Pharmacokinetics of Doxycycline in Skin of Healthy Volunteers Doxycycline - Rosacea | Phase 1 | Completed | Medical University of Vienna | 6 | 2016-07-01 | 2018-03-27 |
| Evaluation of the Inhibitory Effects of Topical Ivermectin on Markers of Rosacea Specific Inflammation. Ivermectin - Rosacea | Phase 1 / Phase 2 | Completed | University of California, San Diego | 25 | 2016-07-01 | 2021-10-05 |
| Timolol for the Treatment of Acne and Rosacea Timolol - Acne Vulgaris, Rosacea | Phase 1 | Completed | Johns Hopkins University | 8 | 2016-03-01 | 2021-11-11 |
| A 21 Day Pharmacokinetics Study in Papulopustular Rosacea CLS001 - Papulopustular Rosacea | Phase 1 | Completed | Maruho Co., Ltd. | 25 | 2014-01-01 | 2014-04-14 |
| An Analysis of the Effect of Topical Cromolyn Sodium on Rosacea-associated Erythema Cromolyn Sodium, Normal Saline - Papulopustular Rosacea | Phase 1 / Phase 2 | Completed | University of California, San Diego | 10 | 2013-08-01 | 2019-08-07 |
| Safety and Tolerability of AGN-199201 in Patients With Erythema Associated With Rosacea AGN-199201 Formulation A, AGN-199201 Formulation B, AGN-199201 Formulation C - Rosacea, Erythema | Phase 1 | Completed | Allergan | 64 | 2012-04-01 | 2019-11-18 |
Showing 20 of 27. Sign in to see all of them.
Erythema (3) · Acne Vulgaris (2) · Telangiectasis (2) · Corneal Neovascularization (1) · Flushing (1)
Skin Diseases (27) · Skin and Connective Tissue Diseases (27) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (3) · Skin Manifestations (3) · Acneiform Eruptions (2) · Cardiovascular Diseases (2) · Sebaceous Gland Diseases (2) · Vascular Diseases (2) · Corneal Diseases (1) · Eye Diseases (1) · Metaplasia (1) · Neovascularization, Pathologic (1) · Pathologic Processes (1)
Ivermectin (2) · Metronidazole (2) · azelaic acid (2) · BID protein, human (1) · Calcium Dobesilate (1) · Cromolyn Sodium (1) · Doxycycline (1) · Gabapentin (1) · Gels (1) · Hydroxychloroquine (1) · Lasers, Dye (1) · MK-0524 (1) · Minocycline (1) · Saline Solution (1) · Sodium Chloride (1)
Sun Pharmaceutical Industries, Inc. (4) · CAGE Bio Inc. (2) · University of California, San Diego (2) · AiViva BioPharma, Inc. (1) · Albany Research Institute, Inc. (1) · Allergan (1) · Anne Chang (1) · Azitra Inc. (1) · Dr.dr.Irma Bernadette, SpKK (K) (1) · Ellen Marmur (1) · First Affiliated Hospital of Chongqing Medical University (1) · Humanis Saglık Anonim Sirketi (1) · Johns Hopkins University (1) · Journey Medical Corporation (1) · LEO Pharma (1)
United States (20) · Austria (1) · China (1) · India (1) · Indonesia (1)
Natalie Yantovskiy (2) · Anne Chang, MD (1) · Ellen Marmur, MD (1) · Gerald D Weinstein, MD (1) · Ika Anggraini, MD (1) · Irma Bernadette Sitohang, MD (1) · Jacqueline Busingye, MD (1) · Luis A Garza, MD, PhD (1) · Mark V. Dahl, M.D. (1) · Markus Zeitlinger (1) · Mitchell Goldman, MD (1) · Reza Dana, MD, MPH, MSc (1)
PMID 23233252, PMID 25142778, PMID 32360760, PMID 32989925, PMID 33548303, PMID 34840653, PMID 35385049, PMID 35929658, PMID 39136023, PMID 39148964, PMID 39681269, PMID 39710117