10 terminated. 10 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Terminated 10 |
| Phase 2 | 4 | Terminated 4 |
Follow Rhabdomyosarcoma: new trials by email Literature Review of Rhabdomyosarcoma trials Research Report on Rhabdomyosarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants LN-145/LN-144 - Soft Tissue Sarcoma, Primary Central Nervous System Carcinoma | Phase 1 | Terminated | Iovance Biotherapeutics, Inc. | 5 | 2024-03-28 | 2026-10-16 |
| Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors Topotecan, Temozolomide, Ribociclib - Neuroblastoma | Phase 1 | Terminated | Novartis Pharmaceuticals | 12 | 2022-12-27 | 2025-10-10 |
| A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer Nivolumab, NKTR-214 - Ependymoma, Ewing Sarcoma | Phase 1 / Phase 2 | Terminated | Bristol-Myers Squibb | 15 | 2021-06-03 | 2023-03-24 |
| Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients Copanlisib (BAY806946) - Relapsed or Refractory Solid Tumors or Lymphoma in Children, Neuroblastoma | Phase 1 / Phase 2 | Terminated | Bayer | 31 | 2018-04-30 | 2023-12-04 |
| Insulin-like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination With the Src Family Kinase (SFK) Inhibitor Dasatinib in People With Embryonal and Alveolar Rhabdomyosarcoma Dasatinib, Ganitumab - Rhabdomyosarcoma, Rhabdomyosarcoma, Alveolar | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 14 | 2017-07-07 | 2022-04-14 |
| Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms Tumors Stereotactic Body Radiotherapy (SBRT) - Ewing Sarcoma, Rhabdomyosarcoma | Phase 1 / Phase 2 | Terminated | Dana-Farber Cancer Institute | 5 | 2017-01-01 | 2021-04-30 |
| A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors Magnetic resonance high intensity focused ultrasound, Lyso-thermosensitive liposomal doxorubicin - Pediatric Cancer, Solid Tumors | Phase 1 | Terminated | AeRang Kim | 2 | 2016-10-01 | 2023-08-29 |
| HGS-ETR2 to Treat Children With Solid Tumors Lexatumumab alone, Lexatumumab in combination, Interferon gamma 1b in combination - Ewing's Sarcoma, Osteosarcoma | Phase 1 | Terminated | National Cancer Institute (NCI) | 30 | 2006-12-04 | 2019-12-17 |
| Radiolabeled MAB Therapy in Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer Iodine I 131 MOAB 8H9 - Brain and Central Nervous System Tumors, Neuroblastoma | Phase 1 | Terminated | Y-mAbs Therapeutics | 177 | 2004-02-05 | 2023-12-26 |
| Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors amifostine trihydrate, busulfan, filgrastim - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Terminated | Masonic Cancer Center, University of Minnesota | 13 | 1998-11-01 | 2017-11-29 |
Neuroblastoma (7) · Sarcoma, Ewing (7) · Osteosarcoma (5) · Sarcoma (5) · Medulloblastoma (4) · Glioma (3) · Neoplasms (3) · Neuroectodermal Tumors, Primitive, Peripheral (3) · Recurrence (3) · Wilms Tumor (3) · Brain Neoplasms (2) · Central Nervous System Neoplasms (2) · Desmoplastic Small Round Cell Tumor (2) · Ependymoma (2)
Myosarcoma (10) · Neoplasms by Histologic Type (10) · Neoplasms, Connective and Soft Tissue (10) · Neoplasms, Muscle Tissue (10) · Neoplasms, Nerve Tissue (9) · Neoplasms, Bone Tissue (8) · Neoplasms, Connective Tissue (8) · Neoplasms, Germ Cell and Embryonal (8) · Neoplasms, Glandular and Epithelial (8) · Neoplasms, Neuroepithelial (8) · Neuroectodermal Tumors (8) · Neuroectodermal Tumors, Primitive (8) · Neoplasms (7) · Neoplasms by Site (6) · Neuroectodermal Tumors, Primitive, Peripheral (5)
Amifostine (1) · Bone Marrow Transplantation (1) · Busulfan (1) · Dasatinib (1) · Filgrastim (1) · Granulocyte Colony-Stimulating Factor (1) · Interferon-gamma (1) · Melphalan (1) · Nivolumab (1) · Peripheral Blood Stem Cell Transplantation (1) · Radiosurgery (1) · Receptor Protein-Tyrosine Kinases (1) · Temozolomide (1) · Thiotepa (1) · Topotecan (1)
National Cancer Institute (NCI) (2) · AeRang Kim (1) · Bayer (1) · Bristol-Myers Squibb (1) · Dana-Farber Cancer Institute (1) · Iovance Biotherapeutics, Inc. (1) · Masonic Cancer Center, University of Minnesota (1) · Novartis Pharmaceuticals (1) · Y-mAbs Therapeutics (1)
United States (10) · Germany (2) · Italy (2) · Australia (1) · France (1) · Spain (1) · United Kingdom (1)
AeRang Kim, MD, PhD (1) · Christine M Heske, M.D. (1) · Crystal L Mackall, M.D. (1) · John P. Perentesis, MD (1) · Karen Marcus, MD (1) · Kim Kramer, MD (1)
PMID 23071222, PMID 31401903, PMID 33047248, PMID 33305087, PMID 36371226, PMID 37398992
2017 (1)