12 completed. 12 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 12 |
| Phase 1 | 1 | Completed 1 |
Follow Retinoblastoma: new trials by email Literature Review of Retinoblastoma trials Research Report on Retinoblastoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations ENV-101 (taladegib) - Solid Tumors With PTCH1 Loss-of-function Mutations | Phase 2 | Completed | Endeavor Biomedicines, Inc. | 20 | 2022-05-24 | 2026-03-05 |
| Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors cixutumumab, laboratory biomarker analysis - Adult Rhabdomyosarcoma, Adult Synovial Sarcoma | Phase 2 | Completed | National Cancer Institute (NCI) | 116 | 2009-01-01 | 2015-03-30 |
| Intra-arterial Chemotherapy(Chemosurgery) for Retinoblastoma Intra-arterial Chemotherapy - Retinoblastoma | Phase 1 / Phase 2 | Completed | Weill Medical College of Cornell University | 100 | 2006-05-01 | 2009-12-17 |
| Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer DNA analysis, immunologic technique, pharmacological study - Brain and Central Nervous System Tumors, Intraocular Melanoma | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 78 | 2006-01-01 | 2024-04-04 |
| Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors arsenic trioxide - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 22 | 2001-03-01 | 2015-11-25 |
| Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma becatecarin - Brain and Central Nervous System Tumors, Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 200 | 2000-07-01 | 2013-02-05 |
| Combination Chemotherapy, Radiation Therapy, and Bone Marrow Transplantation in Treating Patients With Retinoblastoma filgrastim, carboplatin, cyclophosphamide - Retinoblastoma | Phase 2 | Completed | St. Jude Children's Research Hospital | 4 | 1997-11-01 | 2011-10-04 |
| High-Dose Thiotepa Plus Peripheral Stem Cell Transplantation in Treating Patients With Refractory Solid Tumors filgrastim, thiotepa, autologous bone marrow transplantation - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 36 | 1997-09-01 | 2013-03-07 |
| Chemotherapy Treatment for Children With Intraocular Germ-Line Retinoblastoma Carboplatin, VP-16, Local Surgery - Retinoblastoma, Retinal Neoplasms | Phase 2 | Completed | Ann & Robert H Lurie Children's Hospital of Chicago | 30 | 1996-04-01 | 2020-08-05 |
| Carboplatin Plus Vincristine in Treating Children With Retinoblastoma carboplatin, vincristine sulfate - Retinoblastoma | Phase 2 | Completed | St. Jude Children's Research Hospital | 25 | 1996-02-01 | 2011-10-04 |
| Chemotherapy in Treating Patients With Retinoblastoma filgrastim, carboplatin, cisplatin - Retinoblastoma | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 50 | 1995-05-01 | 2013-06-28 |
| Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer filgrastim, carboplatin, thiotepa - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 1992-10-01 | 2013-06-24 |
Neuroblastoma (6) · Sarcoma (6) · Osteosarcoma (5) · Central Nervous System Neoplasms (4) · Medulloblastoma (4) · Ovarian Neoplasms (4) · Desmoplastic Small Round Cell Tumor (3) · Neuroectodermal Tumors, Primitive, Peripheral (3) · Rhabdomyosarcoma (3) · Testicular Neoplasms (3) · Wilms Tumor (3) · Astrocytoma (2) · Burkitt Lymphoma (2) · Chondrosarcoma (2)
Eye Diseases (12) · Eye Diseases, Hereditary (12) · Eye Neoplasms (12) · Neoplasms (12) · Neoplasms by Histologic Type (12) · Neoplasms by Site (12) · Neoplasms, Germ Cell and Embryonal (12) · Neoplasms, Glandular and Epithelial (12) · Neoplasms, Nerve Tissue (12) · Retinal Diseases (12) · Neoplasms, Neuroepithelial (11) · Neuroectodermal Tumors (11) · Retinal Neoplasms (11) · Endocrine Gland Neoplasms (6) · Endocrine System Diseases (6)
Carboplatin (5) · Filgrastim (4) · Etoposide (3) · Cyclophosphamide (2) · Thiotepa (2) · Topotecan (2) · Vincristine (2) · Arsenic Trioxide (1) · Cisplatin (1) · Cryotherapy (1) · Doxorubicin (1) · Immunologic Techniques (1) · LY2940680 (1) · Mesna (1) · Peripheral Blood Stem Cell Transplantation (1)
Memorial Sloan Kettering Cancer Center (5) · National Cancer Institute (NCI) (2) · St. Jude Children's Research Hospital (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Endeavor Biomedicines, Inc. (1) · Weill Medical College of Cornell University (1)
United States (12) · Australia (2) · Canada (2) · Netherlands (1) · New Zealand (1) · Puerto Rico (1) · Switzerland (1)
Brian H. Kushner, MD (2) · Carlos Rodriguez-Galindo, MD (2) · Ira Dunkel, MD (2) · Anne-Marie Langevin, MD (1) · Brenda Weigel, MD (1) · David H Abramson, MD (1) · Kim Kramer, MD (1) · Lisa Lancaster, M.D. (1) · Stewart Goldman, MD (1)
P30CA008748 (2), P30CA021765 (2), P01CA023099 (1), U10CA098543 (1)