27 completed, 9 unknown, 8 recruiting, 3 withdrawn. 17 Not applicable, 7 Phase 1, 5 Phase 2, 2 Phase 4, 1 Phase 3.
Follow Respiratory System Abnormalities: new trials by email Literature Review of Respiratory System Abnormalities trials Research Report on Respiratory System Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Comparative Study of Endoscopic Choanal Canalization and Mitomycin C Application vs Endoscopic Crossover Flap Technique Transnasal Puncture with Mitomycin C application, Endoscopic Crossover Flap Repair - Choanal Atresia | Not applicable | Not yet recruiting | Assiut University | 30 | 2025-09-01 | 2025-09-15 |
| Bronchi Dilation in Polynesian Patients: Monocentric Retrospective Study Polynesian Bronchiectasis | Recruiting | Centre Hospitalier Intercommunal Creteil | 500 | 2025-06-01 | 2026-06-15 | |
| Study of Inhaled RCT1100 in Adults With PCD Caused by Pathogenic Mutations in the DNAI1 Gene to Measure Mucociliary Clearance RCT1100 - Primary Ciliary Dyskinesia (PCD) | Phase 1 | Completed | ReCode Therapeutics | 14 | 2024-10-22 | 2026-04-30 |
| A Study to Assess the Safety, Tolerability, Ciliary Rescue, and Pharmacodynamics of RCT1100 in Adults With PCD RCT1100 - Primary Ciliary Dyskinesia | Phase 1 | Completed | ReCode Therapeutics | 7 | 2024-09-20 | 2025-10-08 |
| Atomized Inhalation ICG for Treatment of Congenital Lung Malformations atomized inhalation ICG before thoracoscope pneumonectomy - Pulmonary Sequestration, Congenital Pulmonary Airway Malformation | Not applicable | Recruiting | Jiexiong Feng | 50 | 2024-03-01 | 2024-10-16 |
| Effect of Ultrasound-guided Erector Spinae Plane Block on Postoperative Pain and Sleep Quality of Infants With Congenital Pulmonary Cystic Disease After Thoracoscopic Surgery Ropivacaine, erector spinae plane block, Incision infiltration of local anesthesia - Cystic Adenomatoid Malformation of Lung, Congenital, Bronchopulmonary Sequestration | Not applicable | Completed | Lei Xiaoming | 68 | 2024-01-09 | 2026-04-22 |
| Laryngeal Allograft Transplantation Larynx Allograft Transplantation - Larynx Stenosis, Larynx Disease | Not applicable | Suspended | Mayo Clinic | 10 | 2023-05-19 | 2026-07-22 |
| Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords Curcumin, Mitomycin-C - Glottic Web of Larynx, Laryngeal Stenosis | Phase 1 / Phase 2 | Recruiting | Eye & ENT Hospital of Fudan University | 100 | 2023-05-05 | 2023-05-06 |
| A Longitudinal, Observational Study of Primary Ciliary Dyskinesia in Adults Spirometry, Multiple Breath Washout (MBW), Mucociliary Clearance (MCC) - Primary Ciliary Dyskinesia | Completed | ReCode Therapeutics | 31 | 2023-03-08 | 2026-05-04 | |
| Study Evaluating the Safety and Tolerability of RCT1100 in Healthy and PCD Subjects RCT1100 - Primary Ciliary Dyskinesia | Phase 1 | Completed | ReCode Therapeutics | 9 | 2023-02-18 | 2025-04-29 |
| The COllaborative Neonatal Network for the First CPAM Trial Elective surgical resection of CPAM between 6 and 9 months of age - Congenital Pulmonary Airway Malformation | Not applicable | Recruiting | Erasmus Medical Center | 176 | 2023-01-01 | 2024-03-04 |
| Distribution of Ventilation, Respiratory Drive and Gas Exchange: Measurements and Monitoring Position change - Pulmonary Disease, Respiratory System Abnormalities | Enrolling by invitation | University of California, San Diego | 40 | 2022-07-19 | 2025-04-11 | |
| Longitudinal Characterization of Respiratory Tract Exacerbations and Treatment Responses in Primary Ciliary Dyskinesia Primary Ciliary Dyskinesia, Kartagener Syndrome | Completed | University of North Carolina, Chapel Hill | 105 | 2022-03-29 | 2025-12-10 | |
| TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era Cystic Fibrosis, Lung Inflammation | Completed | Erasmus Medical Center | 103 | 2022-03-21 | 2025-07-18 | |
| Manual Diaphragm Release in Cleaning Laborer Manual Diaphragm Release, control group - Respiratory System Abnormalities | Not applicable | Completed | Maged Basha | 36 | 2022-03-10 | 2023-04-06 |
| An Integrated Prenatal and Postnatal Treatment Model for the Treatment of Newborns With Critical Congenital Heart Disease Congenital Heart Disease, Coarctation of Aorta | Recruiting | Beijing Anzhen Hospital | 10000 | 2022-01-01 | 2025-01-10 | |
| Continuous Positive Airway Pressure (CPAP) Pediatric Patients With Subglottic Stenosis Who Undergo Balloon Dilatation CPAP group: postoperative CPAP support, non-CPAP group: oxygen 3 liters per minute (L/min) either via mask for those who were extubated or through a T-piece for those with a trash - Airway Complication of Anesthesia, Congenital Subglottic Stenosis | Not applicable | Completed | Umraniye Education and Research Hospital | 81 | 2022-01-01 | 2025-11-19 |
| Characterizing the Upper Airway Manifestations in Primary Ciliary Dyskinesia and Primary Immunodeficiencies Primary Ciliary Dyskinesia, Kartagener Syndrome | Completed | University of North Carolina, Chapel Hill | 159 | 2021-06-09 | 2025-08-21 | |
| Treatment of Laryngotracheal Stenosis Using Mesenchymal Stem Cells Olfactory mucosa-derived mesenchymal stem cells, Patients treated according to current clinical protocols - Tracheal Stenosis, Laryngeal Stenosis | Phase 2 | Unknown | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | 20 | 2021-06-01 | 2022-09-10 |
| Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Post-operative Period Normoxia (with controlled re-oxygenation), Standard of care ventilation - Hypoplastic Left Heart Syndrome, Total Anomalous Pulmonary Venous Return | Not applicable | Completed | University of Michigan | 29 | 2021-01-18 | 2024-06-18 |
Showing 20 of 53. Sign in to see all of them.
Kartagener Syndrome (21) · Ciliary Motility Disorders (20) · Cystic Adenomatoid Malformation of Lung, Congenital (8) · Laryngostenosis (8) · Scimitar Syndrome (5) · Tracheal Stenosis (4) · Bronchopulmonary Sequestration (2) · Choanal Atresia (2) · Cystic Disease Of Lung (2) · Cystic Fibrosis (2) · Heart Defects, Congenital (2) · Hypoplastic Left Heart Syndrome (2) · Laryngeal Diseases (2) · Lung Diseases (2)
Congenital Abnormalities (53) · Respiratory Tract Diseases (53) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (52) · Otorhinolaryngologic Diseases (31) · Cardiovascular Diseases (27) · Cardiovascular Abnormalities (26) · Bronchial Diseases (23) · Heart Diseases (23) · Genetic Diseases, Inborn (22) · Abnormalities, Multiple (21) · Bronchiectasis (21) · Ciliopathies (21) · Dextrocardia (21) · Heart Defects, Congenital (21)
Mitomycin (2) · Spirometry (2) · Aging (1) · Apoptosis (1) · Betamethasone (1) · Blood Specimen Collection (1) · Control Groups (1) · Critical Care (1) · Curcumin (1) · Data Collection (1) · Desflurane (1) · Desmin (1) · Fentanyl (1) · Genetic Testing (1) · Hypnosis (1)
University of North Carolina, Chapel Hill (8) · ReCode Therapeutics (4) · University of Bern (3) · Assistance Publique - Hôpitaux de Paris (2) · Erasmus Medical Center (2) · Guangdong Provincial People's Hospital (2) · Hacettepe University (2) · Umraniye Education and Research Hospital (2) · University of California, San Francisco (2) · Assiut University (1) · Astana Medical University (1) · Beijing Anzhen Hospital (1) · Centre Hospitalier Intercommunal Creteil (1) · Centre Hospitalier Universitaire Vaudois (1) · Centre d'Investigation Clinique et Technologique 805 (1)
United States (20) · Canada (7) · China (6) · Switzerland (5) · France (4) · Turkey (Türkiye) (4) · United Kingdom (3) · Belarus (2) · Netherlands (2) · Australia (1) · Brazil (1) · Denmark (1) · French Polynesia (1) · Germany (1) · Kazakhstan (1)
John Matthews, MBBS, MCRP, PhD (3) · Claudia E Kuehni, Prof (2) · Deniz Inal Ince, Prof. Dr. (2) · Jian Zhuang, M.D., Ph D. (2) · Stephanie Davis, MD (2) · Aalok V Agarwala, MD, MBA (1) · Alex Pearce (1) · Aliya Turayeva, PhD (1) · Andrei Hancharou, Dr (1) · Andrei Y Hancharou, Dr (1) · Arjunan Ganesh, MD (1) · Catherine Hart, MD (1) · Christophe Delacourt, MD, PhD (1) · David G Lott, MD (1)
PMID 23477994, PMID 38072392, PMID 15351938, PMID 16627867, PMID 16858015, PMID 17059358, PMID 17449765, PMID 17515466, PMID 18946302, PMID 19961637, PMID 20350728, PMID 21270641, PMID 21514598, PMID 21926392, PMID 21926394, PMID 21926395, PMID 21926396, PMID 22177992, PMID 22184204, PMID 22276227, PMID 22328589, PMID 22499950, PMID 23040496, PMID 23798057, PMID 23849778, PMID 23872636, PMID 23877309, PMID 23891469, PMID 23957500, PMID 24024753, PMID 24055112, PMID 24094744, PMID 24508509, PMID 24577564, PMID 25307158, PMID 26559535, PMID 27070726, PMID 28052956, PMID 29269581, PMID 30049738, PMID 30691261, PMID 31273043, PMID 31533829, PMID 32019538, PMID 32795996, PMID 32899853, PMID 34635525, PMID 35301251, PMID 35415187, PMID 35536410
U54HL096458 (5), 5UL1TR002240-05 (1), I21RX001079 (1), R01HL071798 (1), U54RR019480 (1)