4 completed, 1 recruiting, 1 terminated, 1 withdrawn. 7 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 4, Recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 1, Recruiting 1, Terminated 1, Withdrawn 1 |
Follow Respiratory System Abnormalities: new trials by email Literature Review of Respiratory System Abnormalities trials Research Report on Respiratory System Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Inhaled RCT1100 in Adults With PCD Caused by Pathogenic Mutations in the DNAI1 Gene to Measure Mucociliary Clearance RCT1100 - Primary Ciliary Dyskinesia (PCD) | Phase 1 | Completed | ReCode Therapeutics | 14 | 2024-10-22 | 2026-04-30 |
| A Study to Assess the Safety, Tolerability, Ciliary Rescue, and Pharmacodynamics of RCT1100 in Adults With PCD RCT1100 - Primary Ciliary Dyskinesia | Phase 1 | Completed | ReCode Therapeutics | 7 | 2024-09-20 | 2025-10-08 |
| Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords Curcumin, Mitomycin-C - Glottic Web of Larynx, Laryngeal Stenosis | Phase 1 / Phase 2 | Recruiting | Eye & ENT Hospital of Fudan University | 100 | 2023-05-05 | 2023-05-06 |
| Study Evaluating the Safety and Tolerability of RCT1100 in Healthy and PCD Subjects RCT1100 - Primary Ciliary Dyskinesia | Phase 1 | Completed | ReCode Therapeutics | 9 | 2023-02-18 | 2025-04-29 |
| Clinical Trial of Stem Cell Based Tissue Engineered Laryngeal Implants Stem cell based tissue engineered partial laryngeal implants - Disorder of Upper Respiratory System, Laryngostenosis | Phase 1 / Phase 2 | Withdrawn | University College, London | 2018-04-01 | 2018-06-06 | |
| Treatment of Laryngotracheal Stenosis Using Mesenchymal Stem Cells Olfactory mucosa-derived mesenchymal stem cells - Tracheal Stenosis, Laryngeal Stenosis | Phase 1 / Phase 2 | Completed | The Republican Research and Practical Center for Epidemiology and Microbiology | 12 | 2017-01-03 | 2019-06-07 |
| Prenatal Steroids for Treatment of Congenital Cystic Adenomatoid Malformations (CCAM) Betamethasone, Placebo - Congenital Cystic Adenomatoid Malformation | Phase 1 / Phase 2 | Terminated | University of California, San Francisco | 1 | 2008-04-01 | 2015-03-30 |
Ciliary Motility Disorders (3) · Kartagener Syndrome (3) · Laryngostenosis (3) · Tracheal Stenosis (2) · Cystic Adenomatoid Malformation of Lung, Congenital (1) · Edema (1) · Laryngeal papillomatosis (1)
Congenital Abnormalities (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Respiratory Tract Diseases (7) · Otorhinolaryngologic Diseases (6) · Abnormalities, Multiple (3) · Bronchial Diseases (3) · Bronchiectasis (3) · Cardiovascular Abnormalities (3) · Cardiovascular Diseases (3) · Ciliopathies (3) · Dextrocardia (3) · Genetic Diseases, Inborn (3) · Heart Defects, Congenital (3) · Heart Diseases (3)
Betamethasone (1) · Curcumin (1) · Mitomycin (1)
ReCode Therapeutics (3) · Eye & ENT Hospital of Fudan University (1) · The Republican Research and Practical Center for Epidemiology and Microbiology (1) · University College, London (1) · University of California, San Francisco (1)
United Kingdom (3) · United States (3) · Australia (1) · Belarus (1) · China (1) · Denmark (1) · Germany (1) · New Zealand (1)
John Matthews, MBBS, MCRP, PhD (3) · Andrei Y Hancharou, Dr (1) · Douglas Wilson, MD (1) · Hanmin Lee, MD (1) · Heymut Omran, MD (1) · Kim G Nielsen, Dr Med Sci (1) · Martin Birchall, Prof (1) · Michael Loebinger, MD (1) · Timothy M Crombleholme, MD (1) · Valery L Chekan, Dr (1)