37 completed, 17 recruiting, 13 unknown, 6 not yet recruiting. 19 Not applicable, 3 Phase 1, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 19 | Completed 5, Recruiting 5, Not yet recruiting 3, Unknown 3, Terminated 2, Enrolling by invitation 1 |
| Phase 1 | 3 | Completed 3 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Ciliary Motility Disorders: new trials by email Literature Review of Ciliary Motility Disorders trials Research Report on Ciliary Motility Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Malnutrition and Sarcopenia Among Primary Ciliary Dyskinesia Physical assessments of individuals - Primary Ciliary Dyskinesia (PCD) | Not yet recruiting | Izmir Democracy University | 15 | 2026-08-03 | 2026-07-31 | |
| Comparison of Individuals With Primary Ciliary Dyskinesia and Healthy Controls Physical Evaluations in Children with Primary Ciliary Dyskinesia, Physical Evaluations in Healthy Children - Primary Ciliary Dyskinesia (PCD) | Not yet recruiting | Izmir Democracy University | 30 | 2026-08-01 | 2026-07-31 | |
| Clearance in Primary Ciliary Dyskinesia Exercise, HS pretreatment with Exercise - Primary Ciliary Dyskinesia, PCD | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 8 | 2026-07-30 | 2026-07-13 |
| Digital Physiotherapy for Pediatric Chronic Suppurative Lung Diseases Videoconferencing (Vsee platform), Specially designed website (FysΑΩ) - Chronic Suppurative Lung Disease, Protracted Bacterial Bronchitis | Not applicable | Not yet recruiting | University of Thessaly | 32 | 2026-05-01 | 2026-01-30 |
| Developing Resource Interventions for Healthcare Professionals and Patients to Improve Knowledge About Fertility in Primary Ciliary Dyskinesia Online educational resource, Toolkit for healthcare professionals - Primary Ciliary Dyskinesia (PCD), Fertility | Not applicable | Not yet recruiting | University of Southampton | 30 | 2026-04-01 | 2026-04-15 |
| Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia Glycine, Magnesium+thiamine, Placebo - Primary Ciliary Dyskinesia | Not applicable | Recruiting | Instituto Nacional de Enfermedades Respiratorias | 60 | 2025-10-02 | 2025-11-25 |
| A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine Non applicable - Chronic Obstructive Pulmonary Disease, Asthma | Recruiting | CHU de Reims | 470 | 2025-09-15 | 2026-02-20 | |
| Thermal Spa Treatment and Improvement of Primary Ciliary Dyskinesia balneotherapy - Primary Ciliary Dyskinesia | Not applicable | Recruiting | Association Francaise pour la Recherche Thermale | 35 | 2025-09-05 | 2025-06-19 |
| A Qualitative Study Investigating the Lived Experiences and Impact of Reproductive Issues in Adults With Primary Ciliary Dyskinesia Interview only - Primary Ciliary Dyskinesia (PCD) | Recruiting | University Hospital Southampton NHS Foundation Trust | 30 | 2025-09-02 | 2026-01-22 | |
| Bronchi Dilation in Polynesian Patients: Monocentric Retrospective Study Polynesian Bronchiectasis | Recruiting | Centre Hospitalier Intercommunal Creteil | 500 | 2025-06-01 | 2026-06-15 | |
| Clean Air for Rare MUcociliary Clearance dIsorders Intervention configuration - air purifiers equipped with HEPA and three other filters for efficient particle filtration, Control configuration - air purifier configured to provide sham particle filtration - Primary Ciliary Dyskinesia (PCD), Cystic Fibrosis (CF) | Not applicable | Enrolling by invitation | University of Cyprus | 62 | 2025-05-01 | 2026-02-18 |
| Study of Inhaled RCT1100 in Adults With PCD Caused by Pathogenic Mutations in the DNAI1 Gene to Measure Mucociliary Clearance RCT1100 - Primary Ciliary Dyskinesia (PCD) | Phase 1 | Completed | ReCode Therapeutics | 14 | 2024-10-22 | 2026-04-30 |
| A Study to Assess the Safety, Tolerability, Ciliary Rescue, and Pharmacodynamics of RCT1100 in Adults With PCD RCT1100 - Primary Ciliary Dyskinesia | Phase 1 | Completed | ReCode Therapeutics | 7 | 2024-09-20 | 2025-10-08 |
| Acoustic Waveform Respiratory Evaluation AWARE - Asthma, COPD | Not applicable | Recruiting | Indiana University | 800 | 2024-07-23 | 2026-10-05 |
| Utility of PCD Diagnostics to Improve Clinical Care Nasal Nitric Oxide testing - Primary Ciliary Dyskinesia | Recruiting | Connecticut Children's Medical Center | 50 | 2023-10-17 | 2026-10-05 | |
| A Study Providing Genetic Testing to Find Those Who May Have Primary Ciliary Dyskinesia for Potential Clinical Trials Sano Genetics Testing Kit - Primary Ciliary Dyskinesia | Active not recruiting | ReCode Therapeutics | 150 | 2023-08-31 | 2025-05-11 | |
| Assessment of Oral Health Status of Children With Primary Ciliary Dyskinesia physical and chemical methods, biochemical methods, Oral Findings - Primary Ciliary Dyskinesia, Caries,Dental | Completed | Marmara University | 160 | 2023-06-12 | 2024-10-01 | |
| Evaluating Bronchodilator Response in Patients With Bronchiectasis spirometry, Salbutamol, placebo - Bronchiectasis, Cystic Fibrosis | Not applicable | Unknown | Rambam Health Care Campus | 96 | 2023-05-20 | 2023-07-06 |
| Examining Bronchial Hyperresponsiveness in Primary Ciliary Dyskinesia Lung Function Testing, Phlebotomy, Allergy skin prick testing - Primary Ciliary Dyskinesia, Healthy | Not applicable | Recruiting | Indiana University | 40 | 2023-05-04 | 2025-12-17 |
| A Longitudinal, Observational Study of Primary Ciliary Dyskinesia in Adults Spirometry, Multiple Breath Washout (MBW), Mucociliary Clearance (MCC) - Primary Ciliary Dyskinesia | Completed | ReCode Therapeutics | 31 | 2023-03-08 | 2026-05-04 |
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Kartagener Syndrome (21) · Cystic Fibrosis (18) · Bronchiectasis (6) · Asthma (5) · Motor Activity (4) · Pulmonary Disease, Chronic Obstructive (4) · Primary Immunodeficiency Diseases (3) · Autoimmune Diseases (2) · Disease (2) · Pseudohypoaldosteronism (2) · Sarcopenia (2) · Abortion, Spontaneous (1) · Anxiety Disorders (1) · Bronchial Hyperreactivity (1)
Abnormalities, Multiple (80) · Ciliopathies (80) · Congenital Abnormalities (80) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (80) · Otorhinolaryngologic Diseases (80) · Genetic Diseases, Inborn (79) · Respiratory Tract Diseases (79) · Bronchial Diseases (31) · Bronchiectasis (21) · Cardiovascular Abnormalities (21) · Cardiovascular Diseases (21) · Dextrocardia (21) · Heart Diseases (21) · Respiratory System Abnormalities (21) · Heart Defects, Congenital (20)
Albuterol (2) · Blood Specimen Collection (2) · Respiratory Physiological Phenomena (2) · Spirometry (2) · Apoptosis (1) · Balneology (1) · Bronchodilator Agents (1) · Data Collection (1) · Exercise (1) · Functional Residual Capacity (1) · Genetic Testing (1) · Glycine (1) · Health Personnel (1) · Hysterectomy (1) · Immunoglobulins, Intravenous (1)
University of North Carolina, Chapel Hill (10) · Gazi University (5) · ReCode Therapeutics (5) · University of Bern (4) · Centre Hospitalier Intercommunal Creteil (3) · Hacettepe University (3) · University Hospital Muenster (3) · Ziv Hospital (3) · Indiana University (2) · Izmir Democracy University (2) · National Heart, Lung, and Blood Institute (NHLBI) (2) · The Hospital for Sick Children (2) · University of Southampton (2) · Vanderbilt University Medical Center (2) · Arkansas Children's Hospital Research Institute (1)
United States (28) · Turkey (Türkiye) (12) · Canada (11) · United Kingdom (9) · France (7) · Germany (5) · Israel (5) · Switzerland (5) · Denmark (2) · Australia (1) · Belgium (1) · Cyprus (1) · Czechia (1) · French Polynesia (1) · Greece (1)
John Matthews, MBBS, MCRP, PhD (3) · Claudia E Kuehni, Prof (2) · Deniz Inal Ince, Prof. Dr. (2) · Israel Amirav, MD (2) · Stephanie Davis, MD (2) · Anand Devaraj (1) · Andrew J Lipton, M.D. (1) · Anna Chmelarova, MD (1) · Aslihan Cakmak (1) · Aspasia Mavronasou, PT, MSc, PhD candidate (1)
PMID 23477994, PMID 38072392, PMID 11562511, PMID 16627867, PMID 16858015, PMID 17059358, PMID 17449765, PMID 17515466, PMID 18026621, PMID 20350728, PMID 21270641, PMID 21514598, PMID 21926392, PMID 21926394, PMID 21926395, PMID 21926396, PMID 22177992, PMID 22184204, PMID 22276227, PMID 22328589, PMID 22499950, PMID 23040496, PMID 23798057, PMID 23849778, PMID 23872636, PMID 23891469, PMID 23957500, PMID 24024753, PMID 24055112, PMID 24094744, PMID 24577564, PMID 25226371, PMID 25869032, PMID 26585432, PMID 26659107, PMID 27070726, PMID 27189798, PMID 27259460, PMID 27836958, PMID 28052956, PMID 28978987, PMID 29269581, PMID 30049738, PMID 30691261, PMID 31273043, PMID 31533829, PMID 32899853, PMID 34635525, PMID 34952415, PMID 35120987
U54HL096458 (5), 2015 (1), R01HL071798 (1), R01HL116213 (1), R01HL117836 (1), R01HL170368 (1), U54RR019480 (1)