19 unknown, 16 completed, 9 recruiting, 3 not yet recruiting. 18 Not applicable, 11 Phase 2, 3 Phase 3, 2 Early Phase 1, 2 Phase 1.
Follow Recurrent Pregnancy Loss: new trials by email Literature Review of Recurrent Pregnancy Loss trials Research Report on Recurrent Pregnancy Loss
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Recombinant Human G-CSF in Women With Unexplained Recurrent Miscarriage Placebo control, Recombinant G-CSF - Recurrent Pregnancy Loss, Recurrent Miscarriages | Phase 2 | Recruiting | Fakih IVF Fertility Center | 150 | 2026-07-10 | 2026-07-24 |
| Effects of High-frequency Left Dorsolateral Prefrontal rTMS on Heart-brain Coupling in Women With Recurrent Pregnancy Loss and Elevated BMI Real repetitive transcranial magnetic stimulation, Sham repetitive transcranial magnetic stimulation - Recurrent Pregnancy Loss, Overweight , Obesity | Not applicable | Not yet recruiting | Shenyang Medical College | 60 | 2026-04-28 | 2026-05-01 |
| Effect of Comprehensive Spa Rehabilitation on Female Infertility: A Clinical Study in Adult Women (Infertility-Spa) Comrehensive Spa Treatment (KLP) - Female Infertility, Reproductive Disorders | Not applicable | Recruiting | Institute of Spa and Balneology, public research institution | 55 | 2026-04-15 | 2026-07-14 |
| Study of Endometrial Immune and Microbiological Modifications in Cases of Recurrent Implantation Failure and/or Recurrent Pregnancy Loss Endometrial Biopsy, Vaginal Swab, Blood sample - Recurrent Implantation Failure, Recurrent Pregnancy Loss | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 100 | 2026-04-01 | 2026-02-05 |
| Cardiac Autonomic and Anxiety Regulation Via Closed-loop nEurofeedback in Recurrent Pregnancy Loss Right DLPFC fNIRS-BCI closed-loop neurofeedback (real feedback), Right DLPFC fNIRS-BCI neurofeedback (sham feedback) - Recurrent Pregnancy Loss, Anxiety | Not applicable | Recruiting | Shenyang Medical College | 62 | 2025-12-29 | 2026-04-24 |
| Right Prefrontal Autonomic Mapping in Recurrent Pregnancy Loss With Comorbid Anxiety repetitive transcranial magnetic stimulation(rTMS) - Recurrent Pregnancy Loss, Anxiety Disorders | Not applicable | Completed | Shenyang Jinghua Hospital | 55 | 2025-05-16 | 2026-07-07 |
| Effect of HCQ Combined With LT4 on LBR in Euthyroid Women With URPL and TPO-Ab hydroxychloroquine and levothyroxine, Levothyroxine - Recurrent Pregnancy Loss, Euthyroid With Thyroid Antibodies | Not applicable | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 796 | 2024-11-15 | 2026-09-30 |
| Prednisolone Administration in Patients With Unexplained REcurrent MIscarriages Prednisolone, Placebo - Recurrent Miscarriage, Recurrent Pregnancy Loss | Phase 4 | Recruiting | Leiden University Medical Center | 490 | 2024-01-29 | 2024-05-24 |
| Tender Loving Care for Recurrent Pregnancy Loss Tender loving care intervention - Recurrent Pregnancy Loss | Not applicable | Recruiting | Walter Reed National Military Medical Center | 60 | 2024-01-01 | 2026-04-22 |
| Elucidating the Microbiome in Patients With Recurrent Pregnancy Loss coulture - Microbiome, Recurrent Pregnancy Loss | Unknown | Assuta Ashdod Hospital | 40 | 2022-11-14 | 2022-11-10 | |
| Treatment of Recurrent Pregnancy Loss Using Mesenchymal Stem Cells Mesenchymal stem cells capable of differentiation in the endometrial-decidual direction, Standard treatment according to the clinical protocols - Recurrent Pregnancy Loss | Phase 1 / Phase 2 | Unknown | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | 20 | 2022-11-01 | 2022-08-29 |
| Biweekly Follow-Up and At-Home Ultrasound Reduce Anxiety in Women With Recurrent Pregnancy Loss PulseNmore ES™, Standard Ultrasound - Recurrent Pregnancy Loss | Not applicable | Unknown | Wolfson Medical Center | 50 | 2022-07-15 | 2023-03-22 |
| Prospective Recurrent Pregnancy Loss Registry Data Registry - Recurrent Pregnancy Loss | Recruiting | University of British Columbia | 3000 | 2022-07-12 | 2024-12-13 | |
| Uterine Artery Doppler Changes After Vaginal Administration of Isosorbide Mononitrate In Patients With URPL isosorbide mononitrate, Placebo - Recurrent Pregnancy Loss | Early Phase 1 | Unknown | Al-Azhar University | 60 | 2022-05-01 | 2022-04-22 |
| Aerobe Cycling Training in Women With Unexplained Recurrent Pregnancy Loss Exercise - Recurrent Pregnancy Loss | Not applicable | Active not recruiting | Radboud University Medical Center | 30 | 2022-03-21 | 2025-04-06 |
| Hydroxychloroquine in Unexplained Recurrent Pregnancy Loss Hydroxychloroquine - Recurrent Pregnancy Loss | Phase 1 | Unknown | Ain Shams University | 70 | 2022-03-01 | 2022-02-14 |
| On Pregnancy After Losses - OPAL Study Observation of pregnancies after intake - Recurrent Pregnancy Loss | Not yet recruiting | Leiden University Medical Center | 1931 | 2022-02-01 | 2021-12-22 | |
| Evaluation of Apelin-13 and Apelin-36 in Women With Recurrent Pregnancy Loss Apelin-13, Apelin-36 - Recurrent Pregnancy Loss | Completed | Ain Shams University | 88 | 2022-01-23 | 2023-02-14 | |
| Establishment of Special Disease Cohort for RPLand Study of Impact Mechanism of Early Embryo Development abnormal pre-pregnancy test results that need clinical intervention - Recurrent Pregnancy Loss | Unknown | Women's Hospital School Of Medicine Zhejiang University | 1000 | 2022-01-12 | 2022-01-21 | |
| Maternal and Newborn Safety Profile of Progestogens in EARLY Pregnancy Progestagen - Early Pregnancy Bleeding, Recurrent Pregnancy Loss | Terminated | Center for Epidemiology and Health Research, Germany | 50 | 2021-12-15 | 2023-08-14 |
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Abortion, Spontaneous (11) · Abortion, Habitual (9) · Infertility (8) · Infertility, Female (3) · Anxiety Disorders (2) · Mannose-Binding Protein Deficiency (2) · Obesity (2) · Overweight (2) · Pregnancy Complications (2) · Adenomyosis (1) · Antiphospholipid Syndrome (1) · Congenital Abnormalities (1) · Diabetes, Gestational (1) · Endometriosis (1) · Endometritis (1)
Urogenital Diseases (21) · Female Urogenital Diseases and Pregnancy Complications (18) · Pregnancy Complications (13) · Genital Diseases (10) · Female Urogenital Diseases (4) · Genital Diseases, Female (4) · Abortion, Spontaneous (3) · Nutritional and Metabolic Diseases (3) · Pathological Conditions, Signs and Symptoms (3) · Autoimmune Diseases (2) · Body Weight (2) · Immune System Diseases (2) · Infertility (2) · Mental Disorders (2) · Nutrition Disorders (2)
Hydroxychloroquine (5) · Aspirin (4) · Heparin, Low-Molecular-Weight (3) · Blood Specimen Collection (2) · Dalteparin (2) · Heparin (2) · Immunoglobulins, Intravenous (2) · Prednisolone (2) · Prednisone (2) · Thyroxine (2) · Anti-Bacterial Agents (1) · Centrifugation, Density Gradient (1) · Clopidogrel (1) · Dydrogesterone (1) · Enoxaparin (1)
Ain Shams University (5) · Aalborg University Hospital (4) · Leiden University Medical Center (2) · Reprogenetics (2) · Shanghai First Maternity and Infant Hospital (2) · Shenyang Medical College (2) · Stanford University (2) · Al-Azhar University (1) · Assistance Publique - Hôpitaux de Paris (1) · Assuta Ashdod Hospital (1) · Benha University (1) · Center for Epidemiology and Health Research, Germany (1) · Copenhagen University Hospital, Rigshospitalet (1) · Eastern Virginia Medical School (1) · Fakih IVF Fertility Center (1)
China (12) · United States (9) · Denmark (6) · Egypt (6) · France (3) · Canada (2) · Iran (2) · Israel (2) · Netherlands (2) · Turkey (Türkiye) (2) · Belarus (1) · Czechia (1) · Germany (1) · United Arab Emirates (1) · United Kingdom (1)
Lin Tao, MM (3) · Yun-En Liu, MD (3) · Fei Meng, MD (2) · Santiago Munne, PhD (2) · Alison Bartolucci, PhD (1) · Amgad E Abou Gamrah, MD (1) · Andrei Hancharou, Dr (1) · Carl A Laskin, MD (1) · Clare Barnet (1) · David Boedeker, DO (1) · Hassan A Bayomy, MD (1)
PMID 32358837, PMID 32898291, PMID 10632428, PMID 10648016, PMID 12090565, PMID 12765346, PMID 16716321, PMID 17075810, PMID 17166218, PMID 1757934, PMID 18667193, PMID 19390908, PMID 19439078, PMID 19710204, PMID 19819893, PMID 20447951, PMID 20528832, PMID 21095154, PMID 21112094, PMID 21718553, PMID 21871597, PMID 22002012, PMID 22635227, PMID 22889462, PMID 23942472, PMID 24581729, PMID 24628478, PMID 24818590, PMID 24917564, PMID 24995856, PMID 25280034, PMID 25305214, PMID 25653897, PMID 25681385, PMID 26371706, PMID 26384980, PMID 26429521, PMID 27100512, PMID 27756248, PMID 29619224, PMID 30776296, PMID 32907619, PMID 33033011, PMID 35747402, PMID 36137638, PMID 36153018, PMID 38367686, PMID 39122211, PMID 40537239, PMID 41263919
2016 (1), R01HD105267 (1)