4 recruiting, 3 not yet recruiting, 3 unknown, 1 active not recruiting. 5 Phase 2, 4 Phase 3, 1 Not applicable, 1 Phase 1, 1 Phase 4.
Follow Radiation Proctitis: new trials by email Literature Review of Radiation Proctitis trials Research Report on Radiation Proctitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Chlorophyllin or Placebo With Standard Treatment for Late Radiation Induced Luminal Gastrointestinal Tract Bleeding Chlorophyllin, Sodium Copper Complex, Placebo - Radiation Proctitis, Gastrointestinal Hemorrhage | Phase 3 | Not yet recruiting | Tata Memorial Centre | 200 | 2026-09-15 | 2026-09-23 |
| Soft Tissue Radiation Injury; Patient Reported Evaluation in a Single Centre Cohort Study (STRIPE) Cystitis, Radio Induced, Soft Tissue Radionecrosis (STRN) | Recruiting | Karolinska University Hospital | 1000 | 2026-05-05 | 2026-06-03 | |
| Gut Microbiome in Gynecological Cancer Patients With Pelvic Toxicity: Controls Versus Ozone Treatment. (MicrOzoGineTox) Pelvic Toxicity, Radiation Toxicity | Recruiting | Bernardino Clavo, MD, PhD | 38 | 2026-01-15 | 2026-09-23 | |
| A Phase II Single-Arm Study of High-Bioavailability Curcumin as Neoadjuvant Chemoradiotherapy in Mid-to-Low Rectal Cancer: Integrated Clinical and Translational Analysis of Tumor Tissue Curcumin (BCM-95®) - Rectal Cancer, Locally Advanced Rectal Cancer | Phase 2 | Not yet recruiting | Chang Gung Memorial Hospital | 72 | 2026-01-01 | 2025-11-25 |
| Association Between Clinical Classification and Prognosis in Chronic Radiation Enteropathy Radiotherapy, Radiation Proctitis | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 150 | 2025-12-04 | 2026-09-02 | |
| Evaluate the Distribution and Dynamic Behavior of Nuclide Labeled TH-SC01 Cells in Vivo in Patients With Radiation Proctitis Mesenchymal Stem Cells (MSCs) - Radiation Proctitis | Phase 1 | Not yet recruiting | Jiangsu Topcel-KH Pharmaceutical Co., Ltd. | 6 | 2025-04-01 | 2025-04-13 |
| Dietary Supplements to Treat Radiation-Induced Rectal Injury Butyrate - Radiotherapy, Radiation Proctitis | Phase 2 | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 33 | 2025-01-15 | 2026-08-07 |
| Feasibility of the Maastro Applicator in Rectal Cancer Maastro applicator - Rectal Cancer, Feasibility | Not applicable | Active not recruiting | Maastricht Radiation Oncology | 10 | 2024-08-27 | 2025-08-14 |
| New Local Treatment of Radiation-induced Proctitis Ziverel - Radiation Proctitis | Unknown | Barmherzige Brüder Vienna | 50 | 2022-07-01 | 2022-08-05 | |
| The Effects of Probiotics Combined With Glutamine in the Prevention and Treatment of Radiation Proctitis Live Combined Bifidobacterium and Lactobacillus Tablets、Compound Glutamine Entersoluble capsules - Radiation Proctitis, Probiotics | Phase 2 / Phase 3 | Unknown | West China Hospital | 176 | 2022-04-15 | 2022-07-15 |
| Efficacy of Symbiotic in the Reduction of Acute Radiation Proctitis Symptoms Symbiotic, Maltodextrin - Radiation Proctitis, Prostate Cancer | Phase 2 / Phase 3 | Completed | Federal University of Mato Grosso | 20 | 2012-01-01 | 2013-07-17 |
| Study to Prevent Radiation Induced Damage to Bowel Using a Prebiotic Enhanced Diet. FructoOligoSaccharide, Maltodextrin - Radiation Enteritis, Radiation Proctitis | Phase 3 | Unknown | University College London Hospitals | 220 | 2010-08-01 | 2011-08-11 |
| CryoSpray Ablation(TM)to Determine Safety and Feasibility in Radiation Induced Proctitis Cryo Spray Ablation Group 1, Cryo Spray Ablation Group 2 - Radiation Proctitis, Radiation Induced Proctitis | Phase 4 | Withdrawn | CSA Medical, Inc. | 2008-10-01 | 2015-08-07 | |
| Budesonide Foam Versus Placebo for Prevention of Acute Radiation Proctitis budesonide, Placebo foam - Radiation Proctitis | Phase 2 | Terminated | Dr. Falk Pharma GmbH | 17 | 2008-09-01 | 2012-01-30 |
Radiation Injuries (3) · Gastrointestinal Hemorrhage (2) · Proctitis (2) · Rectal Neoplasms (2) · Cystitis (1) · Dysbiosis (1) · Pathologic Complete Response (1) · Prostatic Neoplasms (1)
Digestive System Diseases (6) · Gastrointestinal Diseases (6) · Intestinal Diseases (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Rectal Diseases (4) · Neoplasms (3) · Neoplasms by Site (3) · Wounds and Injuries (3) · Colorectal Neoplasms (2) · Digestive System Neoplasms (2) · Gastroenteritis (2) · Gastrointestinal Neoplasms (2) · Hemorrhage (2) · Intestinal Neoplasms (2)
maltodextrin (2) · Budesonide (1) · Butyrates (1) · Cryotherapy (1) · Curcumin (1) · chlorophyllin (1) · fructooligosaccharide (1)
Sixth Affiliated Hospital, Sun Yat-sen University (2) · Barmherzige Brüder Vienna (1) · Bernardino Clavo, MD, PhD (1) · CSA Medical, Inc. (1) · Chang Gung Memorial Hospital (1) · Dr. Falk Pharma GmbH (1) · Federal University of Mato Grosso (1) · Jiangsu Topcel-KH Pharmaceutical Co., Ltd. (1) · Karolinska University Hospital (1) · Maastricht Radiation Oncology (1) · Tata Memorial Centre (1) · University College London Hospitals (1) · West China Hospital (1)
China (3) · Austria (1) · Germany (1) · India (1) · Netherlands (1) · Spain (1) · Sweden (1) · Taiwan (1) · United Kingdom (1)
Alastair Forbes, Bsc;MD;FRCP;FHEA (1) · Anders Kjellberg, MD, PhD (1) · Bernardino Clavo, MD, PhD (1) · Bernhard Dauser, Assoc. Prof. (1) · Jacob Lorenzo-Morales, Prof (1) · Mary Lee Krinsky, D.O. (1) · Prof. Rahul Krishnatry (1) · Ralph Mueller, Dr (1) · Shu-Huan Huang, MD. (1)
PMID 19594223, PMID 19735878, PMID 20046768, PMID 20726007, PMID 30968152, PMID 31108984, PMID 32029014