15 completed, 4 unknown, 1 active not recruiting, 1 not yet recruiting. 15 Not applicable, 3 Phase 3, 2 Phase 1, 2 Phase 2, 1 Early Phase 1.
Follow fructooligosaccharide: new trials by email Literature Review of fructooligosaccharide trials Research Report on fructooligosaccharide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Dietary Carbohydrate Content and Inulin-Fructooligosaccharide Supplementation on Glycemic Control in Individuals With Type 1 Diabetes Mellitus fructooligosaccharide and inulin, Dietary carbohydrate 30%, Dietary carbohydrate 50-55% - Type 1 Diabetes Mellitus | Not applicable | Active not recruiting | Hacettepe University | 30 | 2026-05-11 | 2026-06-29 |
| Inulin-Spirulina Co-intervention for Insomnia Disorder Inulin, Spirulina, Maltodextrin - Insomnia Disorder, Sleep Initiation and Maintenance Disorders | Not applicable | Not yet recruiting | First Affiliated Hospital of Zhejiang University | 180 | 2026-05-01 | 2026-05-19 |
| Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial Psyllium powder, Fructooligosaccharide - Constipation - Functional | Not applicable | Recruiting | Federal University of Minas Gerais | 25 | 2026-03-14 | 2026-03-24 |
| Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD) alpha-lactalbumin, fructooligosaccharides, inulin, alpha-lactalbumin, sodium butyrate, fructooligosaccharides, inulin - CDKL5 | Not applicable | Unknown | University of Milan | 20 | 2024-04-01 | 2024-06-07 |
| Synbiotics and Fecal Microbiota Transplantation to Treat Non-Alcoholic Steatohepatitis Lyophilized fecal microbiota transplantation capsules, Placebo capsules, A. soehngenii - Non Alcoholic Steatohepatitis, Non-Alcoholic Fatty Liver Disease | Phase 2 | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 48 | 2023-03-17 | 2024-08-27 |
| Gastrointestinal And Metabolic Effects From a Prebiotic, Lifting, and Aerobic iNtervention Fructooligosaccharides (FOS), Exercise, Placebo - Overweight and Obesity | Not applicable | Unknown | University of Illinois at Urbana-Champaign | 48 | 2021-10-01 | 2022-11-10 |
| Comparing Several Strategies to Manage Moderate Acute Malnutrition Among Children From 6 to 24 Months Old Azythromycin, Inuline and fructo-oligosaccharides, Albendazole - Moderate Acute Malnutrition | Phase 3 | Completed | Institut Pasteur | 1357 | 2018-01-31 | 2022-05-24 |
| Red Raspberry Polyphenols on Gut Microbiome Raspberry and fructooligosaccharide, Raspberry - Healthy Subjects, Pre-diabetes | Not applicable | Completed | Clinical Nutrition Research Center, Illinois Institute of Technology | 30 | 2017-05-18 | 2020-07-14 |
| Fructooligosaccharides in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant Fructooligosaccharide, Laboratory Biomarker Analysis - Hematopoietic and Lymphoid Cell Neoplasm, Recurrent Hematologic Malignancy | Phase 1 | Completed | Stanford University | 15 | 2016-06-01 | 2021-03-23 |
| Influence of Probiotic and Symbiotic in Body Weight, Blood Sugar and Lipemia of Obese Women Probiotic, Symbiotic, Placebo - Obesity | Not applicable | Completed | Universidade Federal do Rio de Janeiro | 32 | 2015-07-01 | 2019-12-10 |
| Prebiotic in Preventing Low Birth Weight Fructooligosaccharide, Pocari-Sweat - Birth Weight <2500gm, Genitourinary Tract Infection | Not applicable | Completed | International Centre for Diarrhoeal Disease Research, Bangladesh | 210 | 2015-06-01 | 2019-03-12 |
| Prebiotic in Chronic Kidney Disease Patients Fructooligosaccharide, Maltodextrin - Chronic Kidney Disease | Not applicable | Completed | Federal University of São Paulo | 50 | 2015-05-01 | 2017-04-07 |
| Microbiome Fructan Metabolism and Symptoms in Childhood IBS Fructan, Maltodextrin - Irritable Bowel Syndrome (IBS) | Not applicable | Completed | Baylor College of Medicine | 55 | 2014-09-01 | 2021-01-22 |
| Gastric Emptying of Rice With Different Starch Properties White rice, low amylose, White rice, high amylose, White rice, slow - Appetitive Behavior | Not applicable | Completed | Purdue University | 12 | 2014-08-01 | 2017-01-30 |
| Satiety Response of Four Dietary Fibers Control, Soluble corn fiber, Resistant starch - Healthy | Early Phase 1 | Completed | University of Minnesota | 20 | 2010-11-01 | 2012-03-29 |
| Study to Prevent Radiation Induced Damage to Bowel Using a Prebiotic Enhanced Diet. FructoOligoSaccharide, Maltodextrin - Radiation Enteritis, Radiation Proctitis | Phase 3 | Unknown | University College London Hospitals | 220 | 2010-08-01 | 2011-08-11 |
| Fructo-oligosaccharides and Irritable Bowel Syndrome Fructo-oligosaccharides, Maltodextrins - Irritable Bowel Syndrome | Not applicable | Completed | Beghin-Meiji | 60 | 2009-03-01 | 2011-01-17 |
| Effects of follow-on Formula Enriched on Short-chain Fructooligosaccharides (scFOS) on Immune Response in Healthy Infants Follow-on formula supplemented with fructo-oligosaccharides, Follow-on formula enriched with placebo (maltodextrins) - Infant | Not applicable | Completed | Syral | 60 | 2009-03-01 | 2011-04-13 |
| Fructooligosaccharide and Calcium Absorption in Adolescent Girls Fructooligosaccharide - Osteoporosis | Phase 1 / Phase 2 | Completed | Purdue University | 26 | 2009-01-01 | 2018-05-07 |
| Preventing Childhood Antibiotic-associated Diarrhea by Prebiotics Inulin and fructo-oligosaccharides., Placebo - Antibiotic-Associated Diarrhea | Phase 3 | Completed | Soroka University Medical Center | 200 | 2008-12-01 | 2012-06-14 |
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Obesity (3) · Irritable Bowel Syndrome (2) · Weight Loss (2) · Appetitive Behavior (1) · Cognitive Dysfunction (1) · Diabetes Mellitus, Type 1 (1) · Epilepsy (1) · Glucose Intolerance (1) · Hematologic Neoplasms (1) · Hyperlipidemias (1) · Motor Activity (1) · Non-alcoholic Fatty Liver Disease (1) · Osteoporosis (1) · Overweight (1) · Renal Insufficiency, Chronic (1)
Purdue University (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Baylor College of Medicine (1) · Beghin-Meiji (1) · Clinical Nutrition Research Center, Illinois Institute of Technology (1) · Federal University of Minas Gerais (1) · Federal University of São Paulo (1) · First Affiliated Hospital of Zhejiang University (1) · Hacettepe University (1) · Institut Pasteur (1) · International Centre for Diarrhoeal Disease Research, Bangladesh (1) · Soroka University Medical Center (1) · Stanford University (1) · Syral (1) · Unilever R&D (1)
United States (6) · Brazil (3) · Netherlands (2) · Spain (2) · Bangladesh (1) · Canada (1) · Central African Republic (1) · France (1) · Israel (1) · Italy (1) · Madagascar (1) · Niger (1) · Senegal (1) · Turkey (Türkiye) (1) · United Kingdom (1)
A.G. Holleboom, MD, PhD (1) · Aglaia Vignoli, MD (1) · Alastair Forbes, Bsc;MD;FRCP;FHEA (1) · Andrew Rezvani (1) · Berdine R Martin, PhD (1) · Britt M Burton-Freeman, Ph.D (1) · Bruno Chumpitazi, MD, MPH (1) · Connie M Weaver, PhD (1) · Edward Haddeman (1) · Jing Lu, PhD (1) · Joanne L Slavin, PhD (1) · Lilian Cupari, PhD (1) · Louise C Oliveira, MD student (1) · Michel Dapoigny, MD, PhD (1) · Muriel Vray, phD (1)
PMID 19056555, PMID 19386741, PMID 28229548, PMID 28970147, PMID 30514364, PMID 33565558, PMID 35421233, PMID 37870148, PMID 39788762, PMID 41230376
K23DK101688 (1), P30CA124435 (1)