7 not yet recruiting, 6 recruiting, 4 completed, 4 unknown. 14 Not applicable, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Not yet recruiting 7, Unknown 4, Recruiting 2, Completed 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 1 | Completed 1 |
Follow Pulmonary Vascular Disease: new trials by email Literature Review of Pulmonary Vascular Disease trials Research Report on Pulmonary Vascular Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Exercise Performance on Ambient Air vs. Low-Flow Liquid Oxygen Therapy in Pulmonary Vascular Disease (PVD) 6-minute walk distance (6MWD) test on ambient conditions, 6-minute walk distance (6MWD) test with supplemental oxygen (LOX) - Pulmonary Vascular Disease, Chronic Thromboembolic Pulmonary Hypertension (CTEPH) | Not applicable | Recruiting | Silvia Ulrich Somaini | 40 | 2026-10-01 | 2026-09-09 |
| Exercise Performance on Ambient Air vs. Low-Flow Liquid Oxygen Therapy in Chronic Lung Diseases 6-minute walk distance (6MWD) test on ambient conditions, 6-minute walk distance (6MWD) test with supplemental oxygen (LOX) - Pulmonary Vascular Disease, Chronic Thromboembolic Pulmonary Hypertension (CTEPH) | Not applicable | Recruiting | Silvia Ulrich Somaini | 40 | 2026-10-01 | 2026-09-09 |
| Assessment of Lung Function (Lufu) at Sea Level LA vs. High Altitude HA in Patients With Pulmonary Arterial Hypertension PAH Re-ascent from sea level to 2850m - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-04 |
| Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH Descent from 2850m to sea level - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-04 |
| Assessment of Six-minute Walking Distance Between Sea Level LA vs. High Altitude HA After Re-ascent in Patients With Pulmonary Arterial Hypertension PAH Re-Ascent sea level to 2850m - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-01 |
| Assessment of Heart Rate Variability HRV During Descent DE From 2850m to Sea Level and During Re-ascent A From Sea Level to 2850m in Patients With Pulmonary Arterial Hypertension PAH Descent and re-ascent (2850m, sea level) - High Altitude Effects, High Altitude | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-03 |
| Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH Descent to sea level - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-03 |
| Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH Descent from 2850m to sea level - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-04 |
| Assessment of Total Pulmonary Resistance sPAP/CO Between Sea Level LA vs. High Altitude HA After Re-ascent in Patients With Pulmonary Arterial Hypertension PAH Re-Ascent from sea level to 2850m - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-04 |
| A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease Echocardiogram - Pulmonary Vascular Disease, Valvular Heart Disease | Recruiting | Mayo Clinic | 600 | 2026-04-28 | 2026-06-18 | |
| Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume Heart Failure, Pulmonary Vascular Disease | Recruiting | Mayo Clinic | 800 | 2024-07-30 | 2026-08-20 | |
| High Altitude (HA) Residents With Pulmonary Vascular Diseases (PVD), 6 Minute Walk Distance (6MWD) Assessed at 2840m (HA) With and Without Supplemental Oxygen Therapy (SOT) 6-minute walk distance (6MWD) test, 6-minute walk distance (6MWD) test with supplemental oxygen (3 l/min, nasal) - Pulmonary Vascular Disease, Pulmonary Artery Hypertension | Not applicable | Unknown | University of Zurich | 24 | 2023-09-23 | 2023-10-05 |
| High Altitude (HA) Residents With Pulmonary Vascular Diseseases (PVD), Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) vs Sea Level (LA) Relocation from HA to LA - Pulmonary Vascular Disease, Pulmonary Arterial Hypertension | Not applicable | Unknown | University of Zurich | 36 | 2023-09-23 | 2023-10-23 |
| HA Residents With PVD, SDB Assessed at HA (2840m) vs LA (Sea Level) Assessment without intervention at High altitude, Relocation to sea level for 2 days - Pulmonary Vascular Disease, Pulmonary Artery Hypertension | Not applicable | Unknown | University of Zurich | 24 | 2023-09-22 | 2023-10-10 |
| Pulmonary Hypertension in Left Heart Disease Transthoracic Echocardiography (TTE), Lung ultrasound - Pulmonary Hypertension, Pulmonary Vascular Disease | Recruiting | Mayo Clinic | 3000 | 2023-07-20 | 2026-03-05 | |
| HA Residents With PVD, 6MWD Assessed at HA (2840m) vs LA (Sea Level) Relocation to sea level - Pulmonary Vascular Disease, Pulmonary Artery Hypertension | Not applicable | Unknown | University of Zurich | 24 | 2023-07-05 | 2023-10-03 |
| Assessing Response to Inhaled Prostacyclin With Hyperpolarized Xe MRI Hyperpolarized 129Xenon gas - Pulmonary Vascular Disease | Phase 2 | Completed | Bastiaan Driehuys | 11 | 2018-03-29 | 2023-10-18 |
| Non-Invasive Diagnosis of Pulmonary Vascular Disease Using Inhaled 129Xe Magnetic Resonance Imaging GE-141, Hyperpolarized 129Xenon gas, MRI - Pulmonary Vascular Disease | Phase 2 | Completed | Bastiaan Driehuys | 62 | 2017-05-03 | 2022-02-22 |
| Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry Pulmonary Vascular Disease, Pulmonary Arterial Hypertension | Recruiting | New York Medical College | 2500 | 2014-10-01 | 2025-03-13 | |
| Evaluation of Dynamic Pulmonary Vascular Resistance in Patients With Closed Ventricular Septal Defect The intervention is performing an exercise test - Pulmonary Vascular Disease | Not applicable | Completed | Universitaire Ziekenhuizen KU Leuven | 45 | 2014-09-01 | 2017-05-05 |
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Pulmonary Arterial Hypertension (13) · Hypertension, Pulmonary (12) · Altitude Sickness (11) · Hypoxia (9) · Familial Primary Pulmonary Hypertension (3) · Sleep Apnea Syndromes (2) · Bronchiectasis (1) · Cystic Fibrosis (1) · Heart Failure (1) · Heart Valve Diseases (1) · Idiopathic Pulmonary Fibrosis (1) · Lung Diseases (1)
Respiratory Tract Diseases (17) · Lung Diseases (16) · Cardiovascular Diseases (14) · Hypertension (12) · Vascular Diseases (12) · Respiration Disorders (11) · Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Signs and Symptoms, Respiratory (9) · Hypertension, Pulmonary (3) · Apnea (2) · Dyssomnias (2) · Heart Diseases (2) · Nervous System Diseases (2) · Sleep Disorders, Intrinsic (2)
Echocardiography (2) · Restraint, Physical (1) · Sodium Chloride (1)
Silvia Ulrich Somaini (9) · University of Zurich (4) · Mayo Clinic (3) · Bastiaan Driehuys (2) · Neovii Biotech (1) · New York Medical College (1) · Universitaire Ziekenhuizen KU Leuven (1)
Switzerland (13) · United States (7) · Canada (2) · Australia (1) · Austria (1) · Belgium (1)
Rodrigo Hoyos (7) · Silvia Ulrich (7) · Barry Borlaug, MD (3) · Rodrigo Hoyos, Dr. (3) · Silvia Ulrich, Prof. Dr. (3) · Silvia Ulrich, Prof. Dr. med. (2) · Angela Bates, MD (1) · Bastiann Driehays, PhD (1) · Catherine Avitabile, MD (1) · David D Ivy, MD (1) · Delphine Yung, MD (1) · Eric Austin, MD (1) · Erika Rosenzweig, MD (1) · Grace Freire, MD (1)
R01HL162828 (1), U01HL121518 (1)