6 completed, 3 active not recruiting, 3 recruiting, 1 unknown. 2 Phase 2, 1 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Not applicable | 1 | Recruiting 1 |
| Phase 1 | 1 | Unknown 1 |
Follow Progressive Muscular Atrophy: new trials by email Literature Review of Progressive Muscular Atrophy trials Research Report on Progressive Muscular Atrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease Whole-body Electrical Muscle Stimulation Exercise - Neuromuscular Diseases (NMD), Amyotrophic Lateral Sclerosis | Not applicable | Recruiting | University of Missouri-Columbia | 50 | 2026-03-10 | 2026-03-17 |
| Digital Assessment of Speech and Fine Motor Control in ALS Digital Speech and Handwriting Assessment - Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis | Completed | Milton S. Hershey Medical Center | 42 | 2024-07-01 | 2026-06-29 | |
| Comprehensive Analysis Platform To Understand, Remedy and Eliminate ALS Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis | Recruiting | University of Alberta | 150 | 2021-09-12 | 2026-04-13 | |
| Phenotype, Genotype and Biomarkers 2 Amyotrophic Lateral Sclerosis, Hereditary Spastic Paraplegia | Active not recruiting | University of Miami | 217 | 2021-01-08 | 2026-06-15 | |
| TRIAL READY (Clinical Trial Readiness) Amyotrophic Lateral Sclerosis, Frontotemporal Dementia | Active not recruiting | University of Miami | 610 | 2019-01-22 | 2026-06-15 | |
| Study of ALS Reversals 4: LifeTime Exposures Amyotrophic Lateral Sclerosis, Progressive Muscular Atrophy | Completed | Duke University | 25 | 2018-09-26 | 2023-01-20 | |
| Study of ALS Reversals 2: Genetic Analyses Amyotrophic Lateral Sclerosis, Progressive Muscular Atrophy | Completed | Duke University | 26 | 2018-06-22 | 2024-01-11 | |
| Clinical Procedures to Support Research in ALS Amyotrophic Lateral Sclerosis, ALS-Frontotemporal Dementia | Recruiting | University of Miami | 1200 | 2018-02-15 | 2026-06-15 | |
| A Patient Centric Motor Neuron Disease Activities of Daily Living Scale Web-based Survey - Amyotrophic Lateral Sclerosis, Progressive Muscular Atrophy | Completed | University of South Florida | 410 | 2016-12-01 | 2019-10-16 | |
| Autologous Bone Marrow-Derived Stem Cell Therapy for Motor Neuron Disease Stem Cells - Motor Neuron Disease, Amyotrophic Lateral Sclerosis | Phase 1 / Phase 2 | Unknown | Stem Cells Arabia | 40 | 2016-09-01 | 2018-06-06 |
| Answer ALS: Individualized Initiative for ALS Discovery Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis | Completed | Johns Hopkins University | 1049 | 2015-12-01 | 2020-01-13 | |
| Phenotype, Genotype & Biomarkers in ALS and Related Disorders Amyotrophic Lateral Sclerosis, Frontotemporal Dementia | Active not recruiting | University of Miami | 708 | 2015-04-01 | 2026-06-15 | |
| Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease Levetiracetam - Motor Neuron Disease, Amyotrophic Lateral Sclerosis | Phase 2 | Completed | Duke University | 20 | 2006-05-01 | 2013-06-19 |
Amyotrophic Lateral Sclerosis (13) · Motor Neuron Disease (13) · Muscular Atrophy, Spinal (13) · Spastic Paraplegia, Hereditary (4) · Frontotemporal Dementia (3) · Disease Progression (2) · Amyotrophy, monomelic (1) · Bulbar Palsy, Progressive (1) · Charcot-Marie-Tooth Disease (1) · Glycogen Storage Disease Type II (1) · Lambert-Eaton Myasthenic Syndrome (1) · Mitochondrial Myopathies (1) · Muscle Cramp (1) · Muscle Spasticity (1) · Muscular Dystrophy, Facioscapulohumeral (1)
Central Nervous System Diseases (13) · Metabolic Diseases (13) · Nervous System Diseases (13) · Neurodegenerative Diseases (13) · Nutritional and Metabolic Diseases (13) · Proteostasis Deficiencies (13) · Spinal Cord Diseases (13) · TDP-43 Proteinopathies (13) · Neuromuscular Diseases (12) · Brain Diseases (4) · Congenital Abnormalities (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Genetic Diseases, Inborn (4) · Hereditary Sensory and Motor Neuropathy (4) · Heredodegenerative Disorders, Nervous System (4)
BID protein, human (1) · Levetiracetam (1)
University of Miami (4) · Duke University (3) · Johns Hopkins University (1) · Milton S. Hershey Medical Center (1) · Stem Cells Arabia (1) · University of Alberta (1) · University of Missouri-Columbia (1) · University of South Florida (1)
United States (10) · South Africa (2) · Canada (1) · Germany (1)
Michael Benatar, MD, PhD (2) · Richard S Bedlack, MD, PhD (2) · Callyn Kirk, MSPH (1) · James D Berry, MD (1) · Jeffery Krischer, PhD (1) · Jeffrey Statland, MD (1) · Michael Benatar (1) · Michael Benatar, DPhil (1) · Michael Benatar, MBChB, MS, DPhil (1) · Nicholas J Maragakis, MD (1) · Sanjay Kalra, MD (1)
PMID 10540002, PMID 17030772, PMID 17364435, PMID 17709710, PMID 17980667, PMID 19922132, PMID 21706151, PMID 22507681, PMID 23421600, PMID 23944684, PMID 23952636, PMID 24067398, PMID 24070404, PMID 24778202, PMID 25054277, PMID 26205535, PMID 39079071, PMID 39185513, PMID 39270623, PMID 4056836, PMID 41343582, PMID 8229050, PMID 8302340, PMID 8423829, PMID 8639063, PMID 8858057
U54NS092091 (3), U01NS107027 (1), U01TR001263 (1)