5 completed, 3 unknown, 1 recruiting, 1 withdrawn. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Completed 5, Unknown 3, Recruiting 1, Withdrawn 1 |
Follow Primary Ovarian Insufficiency: new trials by email Literature Review of Primary Ovarian Insufficiency trials Research Report on Primary Ovarian Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome Micronized progesterone 200 MG, Micronized Progesterone 100 MG - Turner Syndrome, Primary Ovarian Insufficiency (Poi) | Phase 4 | Recruiting | Children's Mercy Hospital Kansas City | 40 | 2025-07-31 | 2026-08-25 |
| Clinical Observation on Kuntai Capsule in Treating Early-onset Ovarian Hypofunction Kuntai Capsule, Femoston - Primary Ovarian Insufficiency | Phase 4 | Unknown | Affiliated Hospital of Nantong University | 120 | 2021-10-22 | 2022-09-09 |
| Autologous Bone Marrow Stem Cell Ovarian Transplantation to Restore Ovarian Function in Premature Ovarian Failure G-CSF, ASCOT - Premature Ovarian Failure (POF) | Phase 4 | Unknown | Instituto de Investigacion Sanitaria La Fe | 20 | 2018-06-01 | 2018-05-24 |
| IMProving Executive Function Study Lisdexamfetamine, Placebo oral capsule - Cognitive Impairment, RRSO | Phase 4 | Completed | University of Pennsylvania | 69 | 2017-09-22 | 2023-11-18 |
| Filgrastim for Premature Ovarian Insufficiency Filgrastim, Saline - Premature Ovarian Failure | Phase 4 | Completed | South Valley University | 10 | 2016-11-01 | 2021-09-21 |
| Effects of ADSC Therapy in Women With POF Autologous fat grafting - Premature Ovarian Failure | Phase 4 | Unknown | Nanjing University | 4 | 2012-09-01 | 2013-11-06 |
| Estrogen Dosing in Turner Syndrome: Pharmacology and Metabolism 17 B estradiol orally, 17 B estradiol - Turner Syndrome, Hypogonadism | Phase 4 | Completed | Nemours Children's Clinic | 41 | 2009-01-01 | 2023-05-16 |
| Effect of Cetrorelex Acetate on Ovarian Function in Women Undergoing Chemotherapy GnRH antagonist - Ovarian Function, Preservation of Ovarian Function | Phase 4 | Withdrawn | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 2007-07-18 | 2017-07-02 | |
| Flexible GnRH Antagonist vs Flare up GnRH Agonist Protocol in Poor Responders Ganirelix 0.25mg (Orgalutran, Organon, The Netherlands), Arvekap 0.1mg (Triptorelin, Ipsen, France) - Infertility, Premature Ovarian Failure | Phase 4 | Completed | Eugonia | 270 | 2003-09-01 | 2013-12-16 |
| Evaluation of Physiologic and Standard Sex Steroid Replacement Regimens in Women With Premature Ovarian Failure Ethinylestradiol / Norethisterone, Estradiol / Progesterone - Premature Ovarian Failure | Phase 4 | Completed | University of Edinburgh | 42 | 2002-02-01 | 2008-08-12 |
Turner Syndrome (2) · Cognitive Dysfunction (1) · Hypogonadism (1) · Infertility (1) · Premature Birth (1)
Adnexal Diseases (10) · Endocrine System Diseases (10) · Female Urogenital Diseases (10) · Female Urogenital Diseases and Pregnancy Complications (10) · Genital Diseases (10) · Genital Diseases, Female (10) · Gonadal Disorders (10) · Ovarian Diseases (10) · Urogenital Diseases (10) · Cardiovascular Abnormalities (2) · Cardiovascular Diseases (2) · Chromosome Disorders (2) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Disorders of Sex Development (2)
Estradiol (3) · Granulocyte Colony-Stimulating Factor (2) · Progesterone (2) · Dydrogesterone (1) · Ethinyl Estradiol (1) · Filgrastim (1) · LHRH, Ac-Nal(1)-Cpa(2)-Trp(3)-Arg(6)-Ala(10)- (1) · Lisdexamfetamine Dimesylate (1) · Norethindrone (1) · Sodium Chloride (1) · Sugars (1) · Triptorelin Pamoate (1) · femoston (1) · ganirelix (1) · kuntai capsule (1)
Affiliated Hospital of Nantong University (1) · Children's Mercy Hospital Kansas City (1) · Eugonia (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Instituto de Investigacion Sanitaria La Fe (1) · Nanjing University (1) · Nemours Children's Clinic (1) · South Valley University (1) · University of Edinburgh (1) · University of Pennsylvania (1)
United States (4) · China (2) · Chile (1) · Greece (1) · Spain (1) · United Kingdom (1)
Antonio Pellicer, Professor (1) · C. Neill Epperson, MD (1) · Mohammad AM Ahmed, MD (1) · Nelly Mauras, MD (1) · Tazim Dowlut-McElroy, M.D., M.S. (1) · Tryfon Lainas, PhD (1) · W Hamish B Wallace, MD (1) · Yali Hu, Ph.D. (1) · Yuquan Zhang, Professor (1)
PMID 18403419, PMID 21880799, PMID 22343553, PMID 23212100, PMID 23678038