13 unknown, 12 completed, 9 recruiting, 3 terminated. 16 Not applicable, 5 Phase 2, 4 Phase 1, 1 Phase 3, 1 Phase 4.
Follow Primary Liver Cancer: new trials by email Literature Review of Primary Liver Cancer trials Research Report on Primary Liver Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| INPACT: Implementation of Nutritional Support and Physical Activity During Cancer Treatment Multimodal Prehabilitation and Rehabilitation Program, Usual Care - Primary Liver Cancer, Liver Metastasis | Not applicable | Not yet recruiting | General Hospital Groeninge | 103 | 2026-11-01 | 2026-11-10 |
| Different Acupoint Stimulation for Postoperative Gastrointestinal Dysfunction in Primary Liver Cancer Patients Acupoint application, TAES, Combined Intervention - Primary Liver Cancer | Not applicable | Not yet recruiting | Shanghai Zhongshan Hospital | 132 | 2026-10-01 | 2026-08-24 |
| Exploring the Application of 3D Bioprinting for Personalized Treatment in Primary Liver Cancer With Tumor Microenvironment Primary Liver Cancer | Active not recruiting | Peking Union Medical College Hospital | 60 | 2025-10-01 | 2026-02-27 | |
| Y-90 Treatment Response Using Transarterial Radioembolization Lumason, Sonazoid - HCC, Hepatocellular Carcinoma | Phase 2 | Recruiting | Thomas Jefferson University | 30 | 2025-09-11 | 2026-06-10 |
| cfDNA Methylation for Liver Cancer Recurrence Detection plasma GNB4 and Riplet genes methylation detection - Primary Liver Cancer | Recruiting | Wuhan Ammunition Life-tech Co., Ltd | 500 | 2025-09-02 | 2026-03-23 | |
| The Dragon PLC Trial (DRAGON-PLC) Portal Vein Embolization, Hepatic Vein Embolization - Primary Liver Cancer, Hepatocellular Carcinoma (HCC) | Not applicable | Recruiting | Maastricht University | 358 | 2025-04-01 | 2025-05-15 |
| Stereotactic Radiosurgery Versus Radiofrequency Ablation for Primary Liver Cancer Stereotactic Body Radiation Therapy (SBRT), Radiofrequency ablation therapy - Primary Liver Cancer | Phase 2 | Recruiting | Tianjin Medical University Cancer Institute and Hospital | 130 | 2025-01-01 | 2025-01-09 |
| Stroke Volume Variation Versus Central Venous Pressure Guidance for Reducing Perioperative Blood Loss During Open Liver Resection, A Non-inferiority Randomized Controlled Trial High SVV-guided fluid management, Low CVP-guided fluid management - Liver Tumor; Surgery, Primary Liver Tumor, Metastatic Liver | Not applicable | Completed | Chiang Mai University | 70 | 2024-11-25 | 2026-10-22 |
| Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study) HistoSonics Edison System - Liver Neoplasms, Primary Liver Cancer | Recruiting | HistoSonics, Inc. | 5000 | 2024-10-14 | 2026-11-06 | |
| An Exploratory Study on Developing an Integrated Approach Combining Multimodal Imaging and Multi-omics Characterization of Tumor Heterogeneity for Precision Diagnosis and Treatment Optimization in Liver Cancer. Multi-modal ultrasonic imaging system for liver cancer - Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (ICC) | Recruiting | Peking Union Medical College Hospital | 308 | 2024-08-01 | 2025-08-03 | |
| Recurrent Liver Cancer: Reconceptualization and Reevaluation Recurrent Liver Cancer, Primary Liver Cancer | Recruiting | Nanjing Medical University | 300 | 2024-07-01 | 2024-12-12 | |
| the Effect of Nutrition-optimized Prehabilitation on Perioperative Intervention in Primary Liver Carcinoma Nutritional optimization-led triple prehabilitation Intervention, Conventional triple prehabilitation Intervention - Hepatocellular Carcinoma, Liver Carcinoma | Not applicable | Completed | Second Affiliated Hospital, Zhejiang University, School of Medicine | 132 | 2024-05-10 | 2026-11-04 |
| An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer ELUCIDATE - Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma | Recruiting | City of Hope Medical Center | 400 | 2024-03-15 | 2026-07-07 | |
| Precision Dietary Intervention Improves Postoperative Energy Intake, Nutritional Status, and Recovery in Patients Undergoing Hepatectomy for Liver Cancer: A Randomized Controlled Trial Special diet plan and whole protein preparation NUTRICIA for 5 days after liver resection for liver cancer, Conventional dietary intervention - Primary Liver Cancer | Not applicable | Completed | Anhui Provincial Hospital | 139 | 2024-01-04 | 2026-01-20 |
| Multi-center Clinical Study on the Decision Tree of Precision Hepatectomy in China Precision Hepatectomy Decision Tree Primary Liver Cancer, Metastatic Liver Cancer | Unknown | Beijing Tsinghua Chang Gung Hospital | 820 | 2023-08-01 | 2023-08-14 | |
| MRI-guided Holmium-166 Radioembolization MRI-guided radioembolization - Primary Liver Cancer, Non-Resectable Hepatocellular Carcinoma | Not applicable | Unknown | Radboud University Medical Center | 15 | 2023-05-23 | 2023-11-18 |
| Registry on Percutaneous Electrochemotherapy CLINIPORATOR - Primary Liver Cancer, Secondary Liver Cancer | Active not recruiting | Cardiovascular and Interventional Radiological Society of Europe | 250 | 2023-01-25 | 2026-02-06 | |
| Polyvinyl Alcohol Embolization Microspheres Embosphere and chemotherapy drug, Polyvinyl alcohol embolization microspheres (Huihe Medical) and chemotherapy drug - Primary Liver Cancer | Not applicable | Unknown | Shanghai Huihe Medical Technology Co., Ltd | 224 | 2022-12-28 | 2023-03-15 |
| Multi-mode Ablation and Molecular Imaging Multi-omics Study for Digestive-Origin Malignant Liver Tumors Multi-mode tumor treatment system, Radiofrequency ablation therapeutic apparatus - Primary Liver Cancer, Colorectal Cancer Liver Metastases | Not applicable | Unknown | Fudan University | 20 | 2022-10-12 | 2024-09-19 |
| Clinical Validation of a Fractional Administration Device for Holmium-166 SIRT Fractional administration device - Liver Cancer, Liver Metastasis Colon Cancer | Not applicable | Completed | Radboud University Medical Center | 5 | 2022-07-12 | 2023-11-18 |
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Carcinoma, Hepatocellular (44) · Liver Neoplasms (12) · Cholangiocarcinoma (5) · Motor Activity (2) · Pancreatic Neoplasms (2) · Bile Duct Neoplasms (1) · Carcinoma (1) · Carcinoma, Renal Cell (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Echinococcosis, Hepatic (1) · Gallbladder Neoplasms (1) · Hemorrhage (1) · Hepatitis B (1) · Lymphoma (1)
Adenocarcinoma (44) · Digestive System Diseases (44) · Digestive System Neoplasms (44) · Liver Diseases (44) · Neoplasms by Histologic Type (44) · Neoplasms by Site (44) · Neoplasms, Glandular and Epithelial (44) · Carcinoma (43) · Neoplasms (43) · Liver Neoplasms (32) · Behavior (2) · Colonic Diseases (2) · Endocrine Gland Neoplasms (2) · Endocrine System Diseases (2) · Gastrointestinal Diseases (2)
Control Groups (1) · Embolization, Therapeutic (1) · High-Intensity Interval Training (1) · Injections (1) · Lidocaine (1) · Observation (1) · Radiosurgery (1) · Rehabilitation (1) · S-Adenosylmethionine (1) · Saline Solution (1) · antineoplaston A10 (1) · antineoplaston AS 2-1 (1) · entecavir (1) · gadolinium ethoxybenzyl DTPA (1) · phosphomannopentaose sulfate (1)
Beijing Insight Science & Technology Co. Ltd. (2) · Peking Union Medical College Hospital (2) · Radboud University Medical Center (2) · Anhui Provincial Hospital (1) · Beijing Tsinghua Chang Gung Hospital (1) · Boston Scientific Corporation (1) · Burzynski Research Institute (1) · CNBG-Virogin Biotech (Shanghai) Ltd. (1) · Cardiovascular and Interventional Radiological Society of Europe (1) · Chiang Mai University (1) · City of Hope Medical Center (1) · Célia Turco (1) · Duke University (1) · Eastern Hepatobiliary Surgery Hospital (1) · Fubing Wang (1)
China (17) · United States (10) · France (4) · Italy (4) · Belgium (3) · Canada (3) · Germany (3) · Netherlands (3) · Australia (2) · Austria (2) · Spain (2) · Switzerland (2) · Thailand (2) · United Kingdom (2) · Denmark (1)
Ajay Goel, PhD (1) · Bieke Lambert, MD (1) · Brian Czito (1) · Chunling Jiang, PhD (1) · Feng Shen, MD PhD (1) · Franco Orsi, Prof. (1) · Frank Nijsen, PhD (1) · Frank Nijsen, PhD. (1) · Fubing Wang, Doctor (1) · Henning O Nielsen, MD, DMsc (1) · Jennifer L Steel, Ph.D. (1) · John Eisenbrey, PhD (1) · Ming Kuang, Ph.D. (1)
PMID 21940527, PMID 24150192, PMID 30479648, PMID 32238921, PMID 32256673, PMID 34187739, PMID 35476700, PMID 37202261, PMID 40108464
K07CA118576 (1), R21CA303648 (1)