3 completed, 2 not yet recruiting, 2 terminated. 7 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 3, Not yet recruiting 2, Terminated 2 |
| Phase 1 | 1 | Completed 1 |
Follow Prescription Drug Misuse: new trials by email Literature Review of Prescription Drug Misuse trials Research Report on Prescription Drug Misuse
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Naloxone for Opioid Associated Out of Hospital Cardiac Arrest Naloxone 2 MG, Saline 2ml - Heart Arrest, Out-Of-Hospital, Opioid Overdose | Phase 2 | Not yet recruiting | University of California, San Francisco | 98 | 2027-03-01 | 2026-09-11 |
| Serious Game to Teach Opioid Overdose Response Serious game training - Opioid Overdose | Phase 2 | Not yet recruiting | University of Nevada, Reno | 850 | 2026-02-01 | 2024-12-11 |
| Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overdose Intravenous infusion of N-acetylcysteine, Intravenous infusion of Fomepizole (4-MP) - Acetaminophen, Drug Overdose | Phase 2 | Terminated | Richard Dart, MD, PhD | 29 | 2022-09-12 | 2025-11-25 |
| Vaped Marijuana to Attenuate Naloxone-Precipitated Withdrawal Naloxone, Marijuana - Opioid Overdose | Phase 2 | Terminated | New York State Psychiatric Institute | 2 | 2021-11-01 | 2025-03-18 |
| Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use Intranasal naloxone, Intramuscular naloxone, Remifentanil - Drug Overdose | Phase 1 / Phase 2 | Completed | Norwegian University of Science and Technology | 12 | 2014-12-01 | 2018-10-17 |
| A Pilot Study of the Bioavailability of Nasal Naloxone naloxone intranasal, naloxone intravenous - Drug Overdose | Phase 2 | Completed | Norwegian University of Science and Technology | 5 | 2013-08-01 | 2021-11-03 |
| Randomized Trial of Intranasal Versus Intravenous Naloxone in Level of Consciousness in Suspected Opioid Overdose Intranasal naloxone, Intravenous - Morphinan Opioid Overdose | Phase 2 | Completed | Isfahan University of Medical Sciences | 100 | 2007-03-01 | 2011-02-10 |
Drug Overdose (4) · Opiate Overdose (3) · Chemical and Drug Induced Liver Injury (1) · Liver Failure (1) · Out-of-Hospital Cardiac Arrest (1)
Chemically-Induced Disorders (7) · Drug Misuse (7) · Mental Disorders (7) · Substance-Related Disorders (7) · Drug Overdose (3) · Narcotic-Related Disorders (3) · Opioid-Related Disorders (3) · Cardiovascular Diseases (1) · Digestive System Diseases (1) · Drug-Related Side Effects and Adverse Reactions (1) · Heart Arrest (1) · Heart Diseases (1) · Hepatic Insufficiency (1) · Liver Diseases (1)
Naloxone (2) · 4-methylpiperazine-2,6-dione (1) · Remifentanil (1) · Sodium Chloride (1) · nabiximols (1)
Norwegian University of Science and Technology (2) · Isfahan University of Medical Sciences (1) · New York State Psychiatric Institute (1) · Richard Dart, MD, PhD (1) · University of California, San Francisco (1) · University of Nevada, Reno (1)
United States (3) · Norway (2) · Iran (1)
Jermaine Jones, PhD (1) · Nastaran Izadi, A.Professor (1) · Ralph Wang, MD, MAS (1) · Richard Dart, MD, PhD (1) · Toril A Nagelhus Hernes, phd prof (1)
PMID 29568976, PMID 31556537, PMID 37681263, PMID 40839512
2014 (1)