8 unknown, 5 completed, 2 active not recruiting, 1 withdrawn. 6 Not applicable, 1 Early Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Unknown 4, Completed 1, Withdrawn 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Active not recruiting 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Premature Rupture of Membrane: new trials by email Literature Review of Premature Rupture of Membrane trials Research Report on Premature Rupture of Membrane
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Magnesium Sulphate in Premature Rupture of Membranes Magnesium sulfate - Premature Rupture of Membrane | Unknown | Assiut University | 124 | 2024-07-30 | 2024-07-22 | |
| Erythromycin Versus Azithromycin for Preterm Prelabor Rupture of Membranes Erythromycin, Azithromycin - Premature Rupture of Membrane | Phase 3 | Active not recruiting | Inova Health Care Services | 140 | 2024-03-08 | 2026-10-15 |
| Dilapan-S®: A Multicenter US E-registry Dilapan-S - Post Term Pregnancy, Premature Rupture of Membrane | Active not recruiting | Medicem Technology s.r.o. | 1200 | 2020-12-01 | 2024-11-22 | |
| PROMMO Trial: Oral Misoprostol vs IV Oxytocin Misoprostol Oral Product, Intravenous Oxytocin - Premature Rupture of Membrane, Induction of Labor Affected Fetus / Newborn | Early Phase 1 | Completed | University of Wisconsin, Madison | 138 | 2020-10-26 | 2025-08-28 |
| Computerized Cardiotocography Monitoring of Fetuses With pPROM Computerized cardiotocography - Cardiotocography, Premature Rupture of Membrane | Unknown | University of Campania Luigi Vanvitelli | 40 | 2020-06-15 | 2020-11-17 | |
| Preterm Premature Rupture of Fetal Membranes: Cervical Ultrasound and Biological Markers to Diagnose Prematurity (RECHOBIOL) Vaginal secretions collection, Blood sample - Premature Rupture of Membrane | Not applicable | Unknown | University Hospital, Clermont-Ferrand | 170 | 2020-03-10 | 2020-03-16 |
| Spanish Registry of Pregnant Women With COVID-19 Covid19, Pregnancy Complications | Unknown | Puerta de Hierro University Hospital | 3000 | 2020-03-01 | 2020-09-22 | |
| Labor Induction With Misoprostol Versus Oxytocin in Women With Premature Rupture of Membranes Misoprostol, Oxytocin - Prelabor Rupture of Membranes, Premature Rupture of Membrane | Not applicable | Unknown | sammour.rami | 200 | 2019-12-01 | 2020-01-29 |
| Premature Rupture of Membranes at 34 to 37 Weeks' Gestation induction of labor, follow up - Premature Rupture of Membrane | Not applicable | Unknown | Assiut University | 120 | 2019-05-01 | 2019-03-25 |
| Randomized Control Trial of Intracervical Balloon Placement vs Oxytocin in Women With Term PROM and Unripe Cervices Intracervical balloon catheter, Oxytocin - Premature Rupture of Membrane, Unfavorable Cervix | Not applicable | Withdrawn | Northwestern University | 2018-11-01 | 2024-03-26 | |
| The Impact of Amniotic Fluid Index (AFI) on Maternal and Perinatal Outcomes in Pregnant Women With Preterm Premature Rupture of Membranes AFI via transabdominal ultrasonography - Premature Rupture of Membrane, Amniotic Fluid Leakage | Completed | Istanbul Medeniyet University | 48 | 2018-09-01 | 2019-09-24 | |
| HIDRATA Study: Efficacy of a Hydration Protocol in Nulliparous Women During Labor optimal, variability - Labor Long, Nulliparity | Not applicable | Unknown | Puerta de Hierro University Hospital | 130 | 2018-06-01 | 2020-09-23 |
| Correlation Between Premature Rupture of Membranes and Early-onset Neonatal Infections Premature Rupture of Membrane, Neonatal Infection | Completed | Bayi Children's Hospital Affiliated to PLA Army General Hospital, China | 15926 | 2017-08-15 | 2020-04-27 | |
| The Use of Quantitative Pregnancy Test in Amniotic Fluid as a Diagnostic Tool for Rupture of Fetal Membranes assessment of beta subunit of human chorionic gonadotropin - Premature Rupture of Membrane | Not applicable | Completed | Cairo University | 100 | 2017-04-10 | 2017-07-11 |
| Comparison of Two Antibiotic Prophylactic Protocols in Preterm Premature Rupture of the Membranes I.V cefuroxime 750 mg*3/d for 2 days, I.V ampicillin 2 gram x4/d for 2 days, P.O cefuroxime 500 mgx2/d for 5 days - Premature Rupture of Membrane | Phase 4 | Unknown | Western Galilee Hospital-Nahariya | 400 | 2015-11-01 | 2016-12-29 |
| Fetal and Maternal Outcome in Preterm Premature Rupture of Membranes (PPROM) rupture of membrane - Premature Rupture of Membrane | Completed | sarah mohamed hassan | 1011 | 2010-01-01 | 2018-04-09 |
Fetal Membranes, Premature Rupture (16) · Preterm Premature Rupture of the Membranes (3) · Pregnancy, Prolonged (2) · Abruptio Placentae (1) · COVID-19 (1) · Diabetes, Gestational (1) · Fetal Growth Retardation (1) · Fever (1) · Neonatal Sepsis (1) · Oligohydramnios (1) · Pregnancy Complications (1) · Premature Birth (1) · Sepsis (1) · Stillbirth (1)
Female Urogenital Diseases and Pregnancy Complications (16) · Obstetric Labor Complications (16) · Urogenital Diseases (16) · Pregnancy Complications (15) · Pathological Conditions, Signs and Symptoms (5) · Pathologic Processes (4) · Infections (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Inflammation (2) · Systemic Inflammatory Response Syndrome (2) · Body Temperature Changes (1) · Coronaviridae Infections (1) · Coronavirus Infections (1) · Death (1) · Diabetes Mellitus (1)
Oxytocin (2) · Alprostadil (1) · Azithromycin (1) · Blood Specimen Collection (1) · Control Groups (1) · Erythromycin (1) · Labor, Induced (1) · Magnesium Sulfate (1) · Misoprostol (1) · Optimal Pressed Ceramic (1) · Pharmaceutical Preparations (1)
Assiut University (2) · Puerta de Hierro University Hospital (2) · Bayi Children's Hospital Affiliated to PLA Army General Hospital, China (1) · Cairo University (1) · Inova Health Care Services (1) · Istanbul Medeniyet University (1) · Medicem Technology s.r.o. (1) · Northwestern University (1) · University Hospital, Clermont-Ferrand (1) · University of Campania Luigi Vanvitelli (1) · University of Wisconsin, Madison (1) · Western Galilee Hospital-Nahariya (1) · sammour.rami (1) · sarah mohamed hassan (1)
United States (4) · Egypt (2) · Israel (2) · Spain (2) · China (1) · France (1) · Italy (1) · Turkey (Türkiye) (1)
Ana Belen Hernandez Lopez, Miswife (1) · Antonio Saad, MD (1) · Antonio Saad, MD, MBA (1) · Antonio Schiattarella, MD (1) · Denis Gallot (1) · Eman Omran, M.D. (1) · Jacquelyn Adams, MD (1) · Jie Cui (1) · Lei Li (1) · Maya Wolf, MD (1) · Oscar M Martinez Perez, Epidemiologist (1) · Shaodong Hua (1) · Whitney You, MD (1) · Xing Li (1)
PMID 32407901, PMID 32511673, PMID 33972083, PMID 36791845, PMID 36996264