19 recruiting, 13 not yet recruiting, 9 completed, 4 active not recruiting. 34 Not applicable, 3 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 34 | Recruiting 13, Not yet recruiting 12, Active not recruiting 4, Completed 4, Enrolling by invitation 1 |
| Phase 3 | 3 | Recruiting 2, Completed 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Postpartum Depression (PPD): new trials by email Literature Review of Postpartum Depression (PPD) trials Research Report on Postpartum Depression (PPD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Postpartum Care in the NICU Multi-Site Postpartum Doula Support in the NICU - Postpartum, Postpartum Depression (PPD) | Not applicable | Not yet recruiting | Children's Hospital of Philadelphia | 756 | 2027-01-01 | 2026-10-14 |
| AI-Enabled Wearable Monitoring for Detection of Postpartum Depression and Anxiety Postpartum Depression (PPD), Postpartum Anxiety | Not yet recruiting | University of Hawaii | 100 | 2026-12-01 | 2026-10-21 | |
| Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms Contingency Management & Problem Solving Therapy, Usual Care - Postpartum Depression (PPD), Alcohol Use | Not applicable | Recruiting | University of Illinois at Chicago | 30 | 2026-10-01 | 2026-10-13 |
| Deconstructing Maternal Burdens: Doulas and the Community Unite for Health Doula, Standard (non-enhanced) Medicaid doula support - Pregnancy, Post Partum | Not applicable | Recruiting | University of Florida | 516 | 2026-09-15 | 2026-09-28 |
| Treatment With Repetitive Transcranial Magnetic Stimulation in Peripartal Depression Repetitive transcranial magnetic stimulation, Sham repetitive transcranial magnetic stimulation - Depression During Pregnancy, Postpartum Depression (PPD) | Not applicable | Not yet recruiting | Psychiatric University Hospital, Zurich | 60 | 2026-09-01 | 2026-08-19 |
| Routine vs. Early Postpartum Depression Screening: A Pragmatic Clinical Trial Early PPD Screening - Postpartum Depression (PPD) | Not applicable | Not yet recruiting | Massachusetts General Hospital | 428 | 2026-09-01 | 2026-08-12 |
| Brexanolone Lifting Outcomes Of Moms LPCN 1154A, Placebo - Depression, Postpartum, Postpartum Depression (PPD) | Phase 3 | Recruiting | Lipocine Inc. | 120 | 2026-09-01 | 2026-09-16 |
| The Goal is to Examine the Impact of Doula-coordinated, Midwife-delivered Postpartum Care Among Individuals With Preterm Births <34 Weeks' Gestation Requiring NICU Admission. Doula-coordinated, Midwife-delivered postpartum care - Doula Support, Postpartum | Not applicable | Not yet recruiting | University of South Carolina | 350 | 2026-09-01 | 2026-08-26 |
| Parents and Babies Pilot Parents and Babies Virtual Group Intervention, Parents and Babies Hybrid Group Intervention - Perinatal Depression, Postpartum Depression (PPD) | Not applicable | Recruiting | Northwestern University | 16 | 2026-08-03 | 2026-08-06 |
| Informing Implementation of a Circadian-Focused Intervention for Postpartum Depression Light therapy - Postpartum Depression (PPD) | Not applicable | Recruiting | University of Michigan | 30 | 2026-07-29 | 2026-08-14 |
| A Study of MI078 for Postpartum Depression MI078 capsule, Placebo of MI078 capsules - Postpartum Depression (PPD) | Phase 3 | Recruiting | Nanjing Minova Pharmaceutical Co., Ltd. | 200 | 2026-07-10 | 2026-07-23 |
| Midwife-led Childbirth Review and Psychological Outcomes in New Parents Midwife-led childbirth review (MLCR) - Postpartum Depression (PPD), Perinatal Anxiety | Not applicable | Not yet recruiting | Charles University, Czech Republic | 1300 | 2026-07-06 | 2026-07-01 |
| Methyl Donor-Rich Diet in the Postpartum Period Methyl Donor-Rich Dietary Intervention - Postpartum Depression (PPD), Breastfeeding | Not applicable | Recruiting | Istanbul University - Cerrahpasa | 100 | 2026-05-21 | 2026-10-21 |
| The Effect of Lullaby During Bath Time on Mother-Infant Bonding, Postpartum Depression, and Parental Self-Efficacy in Infants Maternal Lullaby Singing - Newborn Infant, Bonding | Not applicable | Not yet recruiting | Istanbul University - Cerrahpasa | 98 | 2026-05-15 | 2026-01-30 |
| mHealth Intervention to Prevent Postpartum Depression and Anxiety in Chilean Women (WWWT) What Were We Thinking (WWWT) mHealth Intervention - Postpartum Depression (PPD), Postpartum Anxiety | Not applicable | Not yet recruiting | Universidad del Desarrollo | 220 | 2026-05-01 | 2026-05-14 |
| Intranasal Dexmedetomidine for Postpartum Depression Prevention Dexmedetomidine, Placebo - Postpartum Depression (PPD) | Not applicable | Not yet recruiting | Chengdu Jinjiang Maternity and Child Health Hospital | 270 | 2026-05-01 | 2026-03-30 |
| Telehealth-Supported Breastfeeding Counseling in Primiparous Mothers Telehealth-Supported Breastfeeding Counseling, Routine Postpartum Care - Breastfeeding, Postpartum Depression (PPD) | Not applicable | Not yet recruiting | Marmara University | 100 | 2026-02-25 | 2026-02-09 |
| NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE) VoiceLove mobile phone application - Postpartum Depression (PPD), Self-Efficacy | Not applicable | Recruiting | Vanderbilt University Medical Center | 150 | 2026-02-04 | 2026-06-17 |
| Evaluating the Effectiveness of an Internet-based Therapy (iCARE) to Treat Symptoms of Postpartum Depression Internet-based therapy (iCARE) and treatment as usual, Treatment as usual (TAU) - Postpartum Depression (PPD) | Not applicable | Recruiting | University of Southern Denmark | 352 | 2026-02-01 | 2026-02-05 |
| Maternal Expectations on Labor Analgesia and Risk of Postpartum Depression: An Observational Study Epidural analgesia, Spinal analgesia for labour pain, No neuraxial analgesia - Postpartum Depression (PPD), Labor Analgesia | Recruiting | University of Padova | 3640 | 2026-01-08 | 2026-04-29 |
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Depression, Postpartum (46) · Depression (5) · Breast Feeding (4) · Psychological Well-Being (4) · Personal Satisfaction (2) · Pregnancy Complications (2) · Alcohol Drinking (1) · Anxiety Disorders (1) · Attention Deficit Disorder with Hyperactivity (1) · Behavioral Symptoms (1) · Cardiovascular Diseases (1) · Depressive Disorder (1) · Diabetes, Gestational (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Jaundice, Neonatal (1)
Depressive Disorder (45) · Female Urogenital Diseases and Pregnancy Complications (45) · Mental Disorders (45) · Mood Disorders (45) · Puerperal Disorders (45) · Urogenital Diseases (45) · Pregnancy Complications (44) · Behavior (16) · Behavioral Symptoms (4) · Feeding Behavior (4) · Pathological Conditions, Signs and Symptoms (3) · Personal Satisfaction (3) · Health Behavior (2) · Pathologic Processes (2) · Treatment Adherence and Compliance (2)
brexanolone (2) · Analgesia, Epidural (1) · Cognitive Behavioral Therapy (1) · Dexmedetomidine (1) · Doulas (1) · Ecological Momentary Assessment (1) · Phototherapy (1) · Therapeutics (1) · Transcranial Magnetic Stimulation (1) · Tuberculin (1) · flocculant protein MO 2.1, Moringa oleifera (1)
Columbia University (2) · Istanbul University - Cerrahpasa (2) · Lipocine Inc. (2) · The Hong Kong Polytechnic University (2) · University of Southern Denmark (2) · University of Virginia (2) · Assistance Publique - Hôpitaux de Paris (1) · Charles University, Czech Republic (1) · Chengdu Jinjiang Maternity and Child Health Hospital (1) · Children's Hospital of Philadelphia (1) · Duzce University (1) · Hong Kong Metropolitan University (1) · Huazhong University of Science and Technology (1) · IWK Health Centre (1) · Istanbul Bilgi University (1)
United States (15) · China (6) · Turkey (Türkiye) (6) · Hong Kong (3) · Canada (2) · Denmark (2) · France (2) · Austria (1) · Czechia (1) · Ethiopia (1) · Germany (1) · Indonesia (1) · Italy (1) · Jordan (1) · Switzerland (1)
Alex Farr, PhD (1) · Andrea Cubitt, PhD (1) · Barbora Provaznikova (1) · Birgit Derntl, Prof., PhD (1) · Catherine Monk, PhD (1) · Elizabeth Werner, PhD (1) · Heather H Burris, MD, MPH (1) · Jennifer L Payne, MD (1) · Lea Takacs, PhD (1) · Leslie Swanson, PhD (1) · Mark A Clapp, MD, MPH (1) · Mary E. D'Alton, MD (1)
PMID 12171026, PMID 26126110, PMID 40384019, PMID 40780718, PMID 41370009, PMID 449366
2023 (1), 2025 (1), K23MD018092 (1), R01HD092062 (1), R01HD121939 (1), R01NR021399 (1), R42MH135602 (1), U54HD113172 (1)