3 recruiting, 2 completed. 2 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Recruiting 2 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
Follow Postoperative Cognitive Decline: new trials by email Literature Review of Postoperative Cognitive Decline trials Research Report on Postoperative Cognitive Decline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prediction and Prevention of Postoperative Mortality and Morbidity Personalized CPC Prehabilitation, Cognitive Training, Meditation - Dementia, Postoperative Delirium (POD) | Not applicable | Recruiting | University of Pittsburgh | 1200 | 2026-10-23 | 2026-11-12 |
| Daridorexant to Prevent Post-cardiotomy Delirium Daridorexant 50 mg, Placebo - Postoperative Cognitive Decline, Postoperative Delirium | Phase 2 | Recruiting | University of Rochester | 80 | 2025-10-14 | 2026-01-07 |
| Daridorexant to Prevent Delirium After Heart Surgery Daridorexant 50 mg, Placebo - POSTOPERATIVE DELIRIUM, POSTOPERATIVE COGNITIVE DECLINE | Phase 2 | Completed | University of Rochester | 11 | 2024-11-11 | 2025-07-11 |
| Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients Cognitive training - Postoperative Cognitive Decline, Postoperative Delirium | Not applicable | Recruiting | Heart and Brain Research Group, Germany | 100 | 2020-08-14 | 2026-02-17 |
| Patients Experiences of Early Postoperative Cognition Cognitive decline - Postoperative Cognitive Decline, Biomarkers | Completed | Karolinska Institutet | 40 | 2019-10-17 | 2023-01-25 |
Postoperative Cognitive Complications (5) · Emergence Delirium (4) · Cognitive Dysfunction (3) · Alzheimer Disease (2) · Delirium (2) · Dementia (1) · Neurocognitive Disorders (1)
Cognition Disorders (5) · Mental Disorders (5) · Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Postoperative Complications (5) · Confusion (4) · Nervous System Diseases (4) · Neurobehavioral Manifestations (4) · Neurocognitive Disorders (4) · Neurologic Manifestations (4) · Signs and Symptoms (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Cognitive Dysfunction (2) · Delirium (2)
Cognitive Training (2) · daridorexant (2) · Meditation (1)
University of Rochester (2) · Heart and Brain Research Group, Germany (1) · Karolinska Institutet (1) · University of Pittsburgh (1)
United States (3) · Germany (1) · Sweden (1)
Marius Butz, Dipl.-Psych. (1) · Mark A Oldham, MD (1) · Senthilkumar Sadhasivam, MD, MPH, MBA (1) · Tibo Gerriets, Prof.Dr.med. (1) · Ulrica Nilsson (1)
2019 (1)