7 completed. 7 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 7 |
| Phase 2 | 1 | Completed 1 |
Follow Polymyositis: new trials by email Literature Review of Polymyositis trials Research Report on Polymyositis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Allogeneic Mitochondria (PN-101) Transplantation for Refractory Polymyositis or Dermatomyositis PN-101 - Polymyositis, Dermatomyositis | Phase 1 / Phase 2 | Completed | Paean Biotechnology Inc. | 9 | 2021-12-15 | 2024-04-03 |
| A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis VIB7734, Placebo - Systemic Lupus Erythematosus, Cutaneous Lupus Erythematosus | Phase 1 | Completed | Amgen | 31 | 2018-12-13 | 2024-12-13 |
| Study of Tofacitinib in Refractory Dermatomyositis Tofacitinib - Dermatomyositis | Phase 1 | Completed | Johns Hopkins University | 10 | 2017-01-01 | 2020-11-06 |
| A Phase 1 Study of MEDI7734 in Type I Interferon-Mediated Autoimmune Diseases MEDI7734, Placebo - Dermatomyositis, Polymyositis, Sjogren's, SLE, SSc | Phase 1 | Completed | Amgen | 36 | 2016-08-26 | 2024-12-13 |
| A Study to Evaluate Safety of Multi-Dose MEDI-545 in Adult Patients With Dermatomyositis or Polymyositis MEDI-545, Placebo - DERMATOMYOSITIS OR POLYMYOSITIS | Phase 1 | Completed | MedImmune LLC | 51 | 2008-04-01 | 2012-05-28 |
| A Pilot Study of Etanercept in Dermatomyositis Etanercept, Placebo - Dermatomyositis | Phase 1 | Completed | Brigham and Women's Hospital | 16 | 2006-03-01 | 2011-06-21 |
| Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders Stem Cell Transplantation, CD34 selection - Systemic Sclerosis, Systemic Lupus Erythematosus | Phase 1 | Completed | Fred Hutchinson Cancer Center | 6 | 2000-11-01 | 2015-03-06 |
Dermatomyositis (7) · Lupus Erythematosus, Systemic (3) · Scleroderma, Systemic (2) · Sjogren's Syndrome (2) · Arthritis (1) · Arthritis, Juvenile (1) · Autoimmune Diseases (1) · Communicable Diseases (1) · Connective Tissue Diseases (1) · Immune System Diseases (1) · Lupus Erythematosus, Cutaneous (1) · Rare Diseases (1)
Muscular Diseases (7) · Musculoskeletal Diseases (7) · Myositis (7) · Nervous System Diseases (7) · Neuromuscular Diseases (7) · Skin Diseases (7) · Skin and Connective Tissue Diseases (7) · Connective Tissue Diseases (6) · Joint Diseases (3) · Rheumatic Diseases (3) · Arthritis (2) · Arthritis, Rheumatoid (2) · Autoimmune Diseases (2) · Dry Eye Syndromes (2)
Etanercept (1) · Sodium Chloride (1) · Stem Cell Transplantation (1) · sifalimumab (1) · tofacitinib (1)
Amgen (2) · Brigham and Women's Hospital (1) · Fred Hutchinson Cancer Center (1) · Johns Hopkins University (1) · MedImmune LLC (1) · Paean Biotechnology Inc. (1)
United States (6) · Poland (1) · South Korea (1) · Spain (1)
Ann Woolfrey (1) · Anthony A Amato, MD (1) · Carol A. Wallace, MD (1) · Daehyun Yoo, MD (1) · Dominique Ethgen, M.D. (1) · Eunyoung Lee, MD (1) · Hyunsook Kim, MD (1) · Julie Paik, MD (1)
PMID 21688301, PMID 23434567, PMID 33258553, PMID 38172601
2018 (1), R01NS049639 (1)