79 completed, 45 recruiting, 24 unknown, 15 terminated. 63 Phase 2, 31 Phase 3, 29 Phase 1, 22 Not applicable, 9 Phase 4.
Follow Polymyositis: new trials by email Literature Review of Polymyositis trials Research Report on Polymyositis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress TEAM-LEADS - Lupus, Dermatomyositis, Juvenile | Not applicable | Not yet recruiting | Duke University | 25 | 2027-02-01 | 2026-05-27 |
| FAST for DM - Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM) FISH OIL 500MG OMEGA-3 SOFT GEL MINIS, Placebo - Dermatomyositis (DM), Juvenile Dermatomyositis (JDM) | Phase 2 | Recruiting | National Institute of Environmental Health Sciences (NIEHS) | 3000 | 2026-11-02 | 2026-10-28 |
| A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases BMS-986553 - Systemic Lupus Erythematosus, Sjögren's Disease | Phase 1 | Not yet recruiting | Bristol-Myers Squibb | 60 | 2026-10-30 | 2026-10-14 |
| BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune Disease LMY-922 - Rheumatoid Arthritis (RA), Systemic Lupus Erthematosus (SLE) | Phase 1 | Not yet recruiting | Luminary Therapeutics | 94 | 2026-10-01 | 2026-07-28 |
| FT839 in Autoimmune Diseases FT839 - ANCA-Associated Vasculitis (AAV), Idiopathic Inflammatory Myositis (IIM) | Phase 1 / Phase 2 | Recruiting | Fate Therapeutics | 446 | 2026-10-01 | 2026-09-02 |
| Pain-Sleep in Rheumatic Disease Better Nights, Better Days for Youth - Rheumatic Diseases, Arthritis | Not applicable | Not yet recruiting | The Hospital for Sick Children | 43 | 2026-09-01 | 2026-08-20 |
| Emapalumab MDA5 Rapidly Progressive Interstitial Lung Disease (RP-ILD) Study Emapalumab - Dermatomyositis, Dermatomyositis Sine Myositis | Phase 2 | Recruiting | University of Miami | 5 | 2026-07-23 | 2026-08-25 |
| Study of NM8074 in Patients with Dermatomyositis (DM) NM8074 - Dermatomyositis | Phase 2 | Not yet recruiting | NovelMed Therapeutics | 8 | 2026-06-01 | 2025-03-25 |
| Exploratory Clinical Study of Anti-CD19/BCMA Universal CAR-T Cell Injection for the Treatment of Refractory Autoimmune Diseases anti-CD19/BCMA-UCAR-T cells - Rheumatoid Arthritis, Dermatomyositis | Not applicable | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 72 | 2026-05-10 | 2026-04-30 |
| Hypnotherapy for Needle-related Procedural Pain and Anxiety Management in a Pediatric Setting Hypnotherapy - Arthritis, Juvenile, Arthritis, Juvenile Idiopathic | Not applicable | Not yet recruiting | Aarhus University Hospital | 70 | 2026-03-01 | 2026-01-20 |
| Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders Descartes-08 - Childhood-onset Systemic Lupus Erythematous, ANCA-Associated Vasculitis (AAV) | Phase 1 / Phase 2 | Recruiting | Cartesian Therapeutics | 50 | 2026-01-14 | 2026-07-27 |
| Construction of a Clinico-Imaging Collaborative Diagnostic Model for Dermatomyositis Combined With Interstitial Lung Disease Based on PET/CT Imaging Features and Clinical Parameters Observe the medical images, Extracting image feature - Dermatomyositis (DM), ILD | Active not recruiting | Ruijin Hospital | 200 | 2026-01-13 | 2026-04-15 | |
| Safety and Efficacy of ULSC on Disease Severity and Steroid Tapering in Participants With Dermatomyositis/ Polymyositis (DM/PM), Also Known as Idiopathic Inflammatory Myopathy (IIM) ULSC (1.5 x 10^8 cells/dose), Placebo (no cells) - Idiopathic Inflammatory Myositis (IIM), DERMATOMYOSITIS OR POLYMYOSITIS | Phase 2 / Phase 3 | Recruiting | Restem, LLC. | 40 | 2026-01-06 | 2026-04-27 |
| Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty Methotrexate, Sulfasalazine, Hydroxychloroquine - Rheumatic Disease | Phase 2 | Recruiting | NYU Langone Health | 80 | 2025-12-12 | 2026-07-09 |
| Phase 2 Trial to Evaluate the Efficacy, Safety of Allogeneic Mitochondria (PN-101) in Patients With Refractory Polymyositis or Dermatomyositis placebo, PN-101 - Polymyositis, Dermatomyositis | Phase 2 | Not yet recruiting | Paean Biotechnology Inc. | 36 | 2025-12-01 | 2025-08-14 |
| A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101 KYV-101 - Refractory Lupus Nephritis, Myasthaenia Gravis | Recruiting | Kyverna Therapeutics | 70 | 2025-11-24 | 2026-02-11 | |
| Study of Deucravacitinib for Refractory Adults With Dermatomyositis/Juvenile Dermatomyositis Deucravacitinb - Myositis, Dermatomyositis | Phase 2 | Withdrawn | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 2025-11-21 | 2025-11-24 | |
| A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease ALLO-329, Cyclophosphamide, Fludarabine - Systemic Lupus Erythematosus (With and Without Nephritis), Idiopathic Inflammatory Myopathy | Phase 1 | Recruiting | Allogene Therapeutics | 66 | 2025-11-13 | 2026-09-10 |
| RCT of Tocilizumab for Anti-MDA5+DM Tocilizumab, Standard medical treatment - Dermatomyositis | Not applicable | Recruiting | Peking Union Medical College Hospital | 110 | 2025-11-01 | 2026-01-29 |
| Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin Diseases Sampling - Atopic Dermatitis, Psoriasis | Recruiting | Assistance Publique - Hôpitaux de Paris | 830 | 2025-10-20 | 2026-06-12 |
Showing 20 of 187. Sign in to see all of them.
Dermatomyositis (181) · Myositis (53) · Lupus Erythematosus, Systemic (30) · Scleroderma, Systemic (27) · Arthritis, Juvenile (21) · Arthritis, Rheumatoid (21) · Autoimmune Diseases (17) · Scleroderma, Diffuse (14) · Sjogren's Syndrome (13) · Myositis, Inclusion Body (11) · Lung Diseases, Interstitial (10) · Rheumatic Diseases (9) · Vasculitis (9) · Connective Tissue Diseases (8)
Nervous System Diseases (186) · Neuromuscular Diseases (186) · Musculoskeletal Diseases (183) · Muscular Diseases (182) · Skin and Connective Tissue Diseases (182) · Skin Diseases (180) · Connective Tissue Diseases (174) · Myositis (134) · Immune System Diseases (55) · Joint Diseases (38) · Autoimmune Diseases (36) · Arthritis (34) · Rheumatic Diseases (29) · Pathological Conditions, Signs and Symptoms (23)
Methotrexate (5) · Tacrolimus (5) · Abatacept (4) · Cyclophosphamide (4) · baricitinib (4) · tocilizumab (4) · Blood Specimen Collection (3) · Etanercept (3) · Glucose (3) · Infliximab (3) · Prednisone (3) · Rituximab (3) · fludarabine (3) · siponimod (3) · sodium thiosulfate (3)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (8) · National Institute of Environmental Health Sciences (NIEHS) (6) · University Hospital, Strasbourg, France (5) · Assistance Publique - Hôpitaux de Paris (4) · Chongqing Precision Biotech Co., Ltd (4) · Karolinska Institutet (4) · Novartis Pharmaceuticals (4) · Pfizer (4) · The First Affiliated Hospital with Nanjing Medical University (4) · Amgen (3) · Duke University (3) · Peking Union Medical College Hospital (3) · The Hospital for Sick Children (3) · University of Sao Paulo (3) · argenx (3)
United States (97) · France (31) · China (28) · Germany (22) · Czechia (21) · Poland (21) · Spain (21) · Italy (20) · United Kingdom (19) · Japan (18) · Canada (15) · Hungary (15) · Netherlands (13) · Brazil (12) · Sweden (12)
Adam I Schiffenbauer, M.D. (4) · Ingrid E Lundberg, MD, PhD (3) · Lisa G Rider, M.D. (3) · Andrew L Mammen, M.D. (2) · Chester V. Oddis, MD (2) · Eloisa Bonfa, MD, PhD (2) · Rohit Aggarwal, MD (2) · Adela Cardones, MD (1) · Ahmed Abdel Khalek Hafez, lecturer (1)
PMID 38059274, PMID 42542380, PMID 15942915, PMID 16914703, PMID 17265499, PMID 17284544, PMID 17407214, PMID 17557758, PMID 19494218, PMID 21540203, PMID 21688301, PMID 21859696, PMID 22089462, PMID 22227955, PMID 22298793, PMID 22733975, PMID 22859354, PMID 22908326, PMID 22931582, PMID 22949223, PMID 22992045, PMID 23070991, PMID 23123020, PMID 23124935, PMID 23139240, PMID 23434567, PMID 23525305, PMID 23588937, PMID 23723319, PMID 23818263, PMID 24961747, PMID 25029335, PMID 25135060, PMID 25223501, PMID 26645190, PMID 27353816, PMID 27353819, PMID 27789240, PMID 28118536, PMID 28399931, PMID 28619061, PMID 28968874, PMID 29134648, PMID 29174792, PMID 29229575, PMID 29237618, PMID 29649002, PMID 30060040, PMID 31314977, PMID 31375890
2016 (2), 2018 (2), 2023 (2), 2008 (1), 2009 (1), K23AR084475 (1), P50AR080612 (1), P60AR047784 (1), R01AR061298 (1), R01NS049639 (1), R21AR066286 (1), UM1CA186688 (1)