5 completed, 3 recruiting, 2 not yet recruiting, 1 enrolling by invitation. 3 Phase 3, 2 Not applicable, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 1, Recruiting 1, Unknown 1 |
| Not applicable | 2 | Completed 1, Enrolling by invitation 1 |
| Phase 4 | 2 | Not yet recruiting 2 |
Follow Pneumocystis: new trials by email Literature Review of Pneumocystis trials Research Report on Pneumocystis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives) Clindamycin + primaquine, Pentamidine, Atovaquone - Pneumocystis, Pneumocystis Infection | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2026-03-01 | 2026-01-21 |
| How Long Should we Give Steroids for Patients With Severe PCP Systemic corticosteroids - Pneumocystis Pneumonia, Pneumocystis | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2026-01-30 | 2026-01-09 |
| Low Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Jirovecii Pneumonia trimethoprim-sulfamethoxazole - Pneumocystis, Pneumocystis Pneumonia | Phase 3 | Recruiting | Todd C. Lee MD MPH FIDSA | 416 | 2025-11-28 | 2026-02-20 |
| Derivation and Validation of the Fungal Pneumonia Assessment and Likelihood Predictor Score FUNGAL-P Score Assessment - Pneumonia, Fungal Pneumonia | Recruiting | Azienda Ospedaliero-Universitaria Careggi | 400 | 2025-11-13 | 2026-07-02 | |
| Optimizing the Diagnosis of Pneumocystis in Immunocompromised Patients Biological sampling - Pneumocystis, Immunocompromised Patients | Recruiting | Assistance Publique - Hôpitaux de Paris | 240 | 2025-07-08 | 2026-04-23 | |
| Prospective Observational Study on the Incidence of Opportunistic Fungal Infections Pneumocystis Jirovecii Infection, Pneumocystis | Completed | University of Colorado, Denver | 12032 | 2023-07-05 | 2025-04-02 | |
| Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation Rezafungin for Injection, Posaconazole, Fluconazole - Candidemia, Mycoses | Phase 3 | Completed | Mundipharma Research Limited | 602 | 2020-05-11 | 2026-04-13 |
| Short-term Steroid Therapy in Patients With P. Jirovecii Pneumonia Due to HIV / AIDS Conventional steroid regimen, Shortened steroid regimen - Pneumocystis, HIV/AIDS | Not applicable | Enrolling by invitation | Centro de Investigación en. Enfermedades Infecciosas, Mexico | 196 | 2019-03-04 | 2026-03-27 |
| Non Invasive Diagnosis of Pneumocystis Pneumonia Sampling of non-invasive and/or non-targeted respiratory tract specimens - Pneumocystis | Not applicable | Completed | University Hospital, Grenoble | 98 | 2018-06-25 | 2023-03-24 |
| Effect of Steroids During Pneumocystis Infection Among Non HIV Immunocompromised Patients Methylprednisolone, Placebo - Pneumocystis, Steroids | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 222 | 2017-02-15 | 2020-10-06 |
| Pneumocystis in Patients Over 75 Year Pneumocystis | Completed | Centre Hospitalier Universitaire de Nīmes | 162 | 2010-01-01 | 2025-06-04 | |
| Prevalence and Pathogenesis of Lung Disease in a Large HIV Cohort-coordinating Center HIV Infections, Emphysema | Completed | University of Pittsburgh | 407 | 2009-01-01 | 2025-08-26 |
Pneumonia, Pneumocystis (12) · Infections (4) · Pneumocystis Infections (4) · Pneumonia (4) · Candidiasis (2) · Mycoses (2) · Acquired Immunodeficiency Syndrome (1) · Aspergillosis (1) · Candidemia (1) · Candidiasis, Invasive (1) · Coinfection (1) · Communicable Diseases (1) · Community-Acquired Pneumonia (1) · Cryptococcosis (1) · Emergencies (1)
Bacterial Infections and Mycoses (12) · Lung Diseases (12) · Lung Diseases, Fungal (12) · Respiratory Tract Diseases (12) · Respiratory Tract Infections (11) · Mycoses (10) · Infections (8) · Pneumocystis Infections (8) · Pneumonia (8) · Pathological Conditions, Signs and Symptoms (3) · Blood-Borne Infections (2) · Communicable Diseases (2) · Disease Attributes (2) · Genital Diseases (2) · Immune System Diseases (2)
Trimethoprim, Sulfamethoxazole Drug Combination (2) · Atovaquone (1) · Clindamycin (1) · Costs and Cost Analysis (1) · Fluconazole (1) · Injections (1) · Methylprednisolone (1) · Off-Label Use (1) · Pentamidine (1) · Primaquine (1) · Rezafungin (1) · posaconazole (1)
Assistance Publique - Hôpitaux de Paris (2) · McGill University Health Centre/Research Institute of the McGill University Health Centre (2) · Azienda Ospedaliero-Universitaria Careggi (1) · Centre Hospitalier Universitaire de Nīmes (1) · Centro de Investigación en. Enfermedades Infecciosas, Mexico (1) · Mundipharma Research Limited (1) · Todd C. Lee MD MPH FIDSA (1) · University Hospital, Grenoble (1) · University of Colorado, Denver (1) · University of Pittsburgh (1)
France (5) · Canada (3) · United States (3) · Italy (2) · Belgium (1) · Germany (1) · Mexico (1) · Spain (1) · Switzerland (1) · United Kingdom (1)
Emily G McDonald, MD MSc (2) · Alison Morris-Gimbel, MD (1) · Elie Azoulay, MD PHD (1) · Gustavo Reyes-Teran, M.D. (1) · Laura Cox, PhD (1) · Lorenzo Pelagatti, MD, PhD (1) · Matthew P Cheng, MD FRCPC (1) · Todd C Lee, MD MPH (1) · Todd C Lee, MD MPH FIDSA (1) · Virginie Lemiale, MD (1)
PMID 25603113, PMID 32479781, PMID 33005696, PMID 33438477, PMID 34349985, PMID 34988242, PMID 35657109, PMID 35863836, PMID 37773627, PMID 38235979, PMID 40652952, PMID 42558999
2016 (1), 2017 (1), R01HL090339 (1)