4 recruiting, 1 terminated. 2 Phase 3, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Recruiting 1, Terminated 1 |
| Phase 4 | 2 | Recruiting 2 |
| Phase 2 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clopidogrel vs. Aspirin for Cardiovascular Risk Reduction in Patients With S. Aureus Bacteremia Clopidogrel, Aspirin - Staphylococcus Aureus Endocarditis, Staphylococcus Aureus Septicemia | Phase 4 | Recruiting | Todd C. Lee MD MPH FIDSA | 300 | 2026-01-15 | 2026-09-24 |
| Low Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Jirovecii Pneumonia trimethoprim-sulfamethoxazole - Pneumocystis, Pneumocystis Pneumonia | Phase 3 | Recruiting | Todd C. Lee MD MPH FIDSA | 416 | 2025-11-28 | 2026-02-20 |
| Adjunctive Rifampin for the Treatment of Prosthetic Valve Endocarditis Due to S. Aureus Rifampin, No rifampin - Staphylococcus Aureus Endocarditis, Prosthetic Valve Endocarditis | Phase 3 | Terminated | Todd C. Lee MD MPH FIDSA | 1 | 2025-11-10 | 2026-09-21 |
| Daptomycin vs. Vancomycin for the Treatment of Methicillin Resistant S. Aureus Bacteremia Daptomycin for Injection, Vancomycin (IV) - Staphylococcus Aureus Septicemia, Staphylococcus Aureus Bacteremia | Phase 4 | Recruiting | Todd C. Lee MD MPH FIDSA | 300 | 2024-11-14 | 2026-09-09 |
| Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia Ertapenem, Placebo - Staphylococcus Aureus Bacteremia, Staphylococcus Aureus Septicemia | Phase 2 | Recruiting | Todd C. Lee MD MPH FIDSA | 60 | 2024-05-20 | 2026-09-11 |
Bacteremia (1) · Infections (1) · Pneumocystis Infections (1) · Pneumonia (1) · Pneumonia, Pneumocystis (1) · Staphylococcal Infections (1)
Aspirin (1) · Clopidogrel (1) · Daptomycin (1) · Ertapenem (1) · Injections (1) · Off-Label Use (1) · Rifampin (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1) · Vancomycin (1)
Canada (5) · Australia (1) · New Zealand (1)
Todd C Lee, MD MPH FIDSA (4) · Emily G McDonald, MD MSc (3) · Matthew P Cheng, MD (1)
2025 (3)